
09/20/2025
“The story starts a half-billion years ago, with the earliest, simplest fish. Their bodies were little more than heads connected to long-ribbon-like bodies; they swallowed food, which made its way down a long digestive tract until the remnants escaped through the a**s…
In 2011, Denis Duboule, a biologist at the University of Geneva, and his colleagues discovered a half-dozen molecular locks sitting side-by-side along a stretch of DNA called 5DOM. …At the far end, 5DOM unlocked the genes for the a**s as well as the opening for its urethra and sexual organs…
But about 360 million years ago, the scientists propose, 5DOM underwent an evolutionary change. Now it could build not only our nether regions but our fingers and toes, too.”
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The evolutionary blueprint for hands was borrowed in part from a much older genetic plan for our nether regions, a new study suggests.