True Path Acupuncture & Wellness

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Mechanistic Insights into Acupuncture for Chronic Prostatitis/Chronic Pelvic Pain Syndrome via Integrated NetworkTopolog...
04/18/2026

Mechanistic Insights into Acupuncture for Chronic Prostatitis/Chronic Pelvic Pain Syndrome via Integrated Network
Topology and Bioinformatics Analysis
Methods: Acupuncture-induced bioactive substances relevant to CP/CPPS were identified
through a systematic literature search, and their putative high-affinity targets were predicted using the STRING database. CP/CPPS-associated genes were collected from GeneCards and DisGeNET with
integrated screening. Overlapping targets were obtained via Venn analysis. Protein-protein interaction (PPI) networks and an “Acupuncture-
Active Substance-Target-CP/CPPS” network were constructed in Cytoscape, and key targets were prioritized using the Maximal Clique Centrality (MCC) algorithm. Functional enrichment analyses
were performed using the Database for Annotation, Visualization and Integrated Discovery (DAVID), which is commonly used for gene functional annotation and enrichment analysis.
Results: We identified 655 shared targets between acupuncture-related components and CP/CPPS. PPI analysis highlighted IL6, IL1B, IFNG, TNE, IL10, CD4, IL4, CXCL10, IL2, and CXCL8 as the top hub targets, and enrichment yielded 1878 significant Gene Ontology (GO) terms, including 214 Kyoto
Encyclopedia of Genes and Genomes (KEGG) pathways.
Conclusion: Acupuncture may exert therapeutic effects in CP/CPPS through coordinated network-level regulation of immune inflammation, tissue repair, and central nervous system remodeling.
Link: https://www.dovepress.com/mechanistic-insights-into-acupuncture-for-chronic-prostatitischronic-p-peer-reviewed-fulltext-article-JPR

Electro acupuncture focused on reducing tightness and pain in the hamstring, hip and glute.
04/18/2026

Electro acupuncture focused on reducing tightness and pain in the hamstring, hip and glute.

Governing Vessel Acupuncture Improves Post-Stroke Cognitive FunctionGoverning vessel acupuncture improves cognitive func...
04/06/2026

Governing Vessel Acupuncture Improves Post-Stroke Cognitive Function
Governing vessel acupuncture improves cognitive function and activities of daily living in patients with post-stroke cognitive impairment when combined with usual care, according to a meta-analysis of 39 randomized controlled trials involving 2044 patients, with 1022 participants in both treatment and control groups. The authors conclude that acupuncture targeting governing vessel points enhances cognitive recovery in stroke survivors. [1]
The analysis demonstrated improvements across multiple validated outcome measures. Montreal Cognitive Assessment (MoCA) scores increased by a mean of 1.82 points and Activities of Daily Living (ADL) scores improved by 5.99 points following treatment courses ranging from 12 to 120 days. The pooled Mini-Mental State
Examination (MMSE) result showed a mean difference of 1.05 points. Subgroup analysis by needling method demonstrated greater improvements in the manual acupuncture subgroup (mean difference 2.18) and electroacupuncture subgroup (mean difference 2.03). The overall clinical response rate also favored acupuncture, with an odds ratio of 3.00 compared with control treatments.[1]

Link: https://www.healthcmi.com/governing-vessel-acupuncture-improves-post-stroke-cognitive-function/

Swipe >There’s no greater honor than helping someone heal 🫶
04/01/2026

Swipe >
There’s no greater honor than helping someone heal 🫶

Deciphering the pharmacodynamic characteristics ofacupuncture and neuromodulation therapies: A novel perspective from or...
03/29/2026

Deciphering the pharmacodynamic characteristics of
acupuncture and neuromodulation therapies: A novel perspective from organoid platforms

Multi-target effects
Acupuncture and neuromodulation therapy have been demonstrated to exhibit multi-target effects,
influencing various systems through multiple mechanisms to treat different diseases. For pain management, Li et al. [7,8] found that electroacupuncture can improve inflammatory pain by upregulating endogenous cannabinoids and ß-endorphins in inflamed skin tissue.
However, rTMS and TENS improve neuropathic pain by inhibiting TRPV1 (transient receptor potential vanilloid-1) channels and ...
Link: https://www.sciencedirect.com/science/article/abs/pii/S1471489226000159

Evaluating the potential of acupuncture for Alzheimer’s disease treatment: A meta-analysis and systematic review of mous...
03/18/2026

Evaluating the potential of acupuncture for Alzheimer’s disease treatment: A meta-analysis and systematic review of mouse model studies. From Nature.com
laboratory settings. We analyzed 29 relevant PubMed articles published between January 2014 and July 2025. Our results reveal that EA significantly reduces both amyloid-beta (Aß) and phosphorylated tau (p-tau) levels and neuroinflammatory biomarkers, including molecular signatures for activated microglia and astrocytes in the brain. EA also enhances cognitive functions. While no study directly compared acupoint strategies, the indirect comparisons in our network analysis suggest that GV20 has potential as a therapeutic target for AD. Our present meta-analysis and review of literature add to the evidence of
integrative health practices for acupuncture-based Alzheimer’s disease treatment.

Link: https://www.nature.com/articles/s41398-026-03923-9

Acupuncture helps to reduce pain, tightness and inflammation, heal from injures, improve circulation, range of motion an...
03/13/2026

Acupuncture helps to reduce pain, tightness and inflammation, heal from injures, improve circulation, range of motion and is great for post workout recovery. 🏋️ 🏊 🏃‍♂️ 💪💃⛷️🩰

Acupuncture Improves Hearing RecoveryAcupuncture improves hearing recovery in patients with sudden sensorineural hearing...
03/11/2026

Acupuncture Improves Hearing Recovery
Acupuncture improves hearing recovery in patients with sudden sensorineural hearing loss (SSNHL), according to a systematic review and meta-analysis of randomized controlled trials involving 2,583 patients.Across 28 trials, acupuncture significantly improved overall treatment effectiveness and hearing thresholds compared with control treatments. Improvements were also observed in tinnitus, and vertigo, while adverse events were generally mild.
Most trials administered acupuncture once daily. Treatment courses commonly ranged from approximately 10 to 30 sessions depending on study design. Many protocols organized therapy into cycles consisting of six days of treatment followed by a one-day break. Needles were typically retained for approximately 20-30 minutes per session. Both manual acupuncture and electroacupuncture were used across studies, although subgroup analysis found electroacupuncture produced superior clinical outcomes.
Clinical outcomes extended beyond hearing thresholds. Many trials evaluated symptom improvements including tinnitus, vertigo, and ear fullness using validated clinical questionnaires such as the Tinnitus Handicap Inventory (THI) and the Dizziness Handicap Inventory (DHI). Improvements in speech recognition scores and other auditory function measures were also reported in some studies.
Link: https://www.healthcmi.com/acupuncture-improves-hearing-recovery/

Such a great honor to help others! 🙏🫶
03/07/2026

Such a great honor to help others! 🙏🫶

The greatest honor is to help others 🙏
02/28/2026

The greatest honor is to help others 🙏

How Acupuncture Calms the Brain in Pain-Induced Emotional DisordersGA, UNITED STATES,February 11, 2026/EINPresswire.com/...
02/22/2026

How Acupuncture Calms the Brain in Pain-
Induced Emotional Disorders
GA, UNITED STATES,
February 11, 2026
/EINPresswire.com/ -
Chronic pain is frequently accompanied by anxiety and depression. New research demonstrates that electroacupuncture can significantly alleviate pain-induced anxiety-and depression-like behaviors by modulating specific excitatory neurons in the brain.
Using a mouse model of nerve injury, the study shows that electroacupuncture activates glutamatergic neurons in a prefrontal brain region involved in emotion regulation, thereby restoring emotional balance without impairing motor function. These findings
provide mechanistic evidence that non-pharmacological neuromodulation can directly target brain circuits underlying pain-related emotional disorders, offering new insights into
integrative approaches for managing chronic pain and its psychological consequences.
Link:
https://www.floridatoday.com/press-release/story/75084/how-acupuncture-calms-the-brain-in-pain-induced-emotional-disorders/

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