Center for Human Reproduction

Center for Human Reproduction World-renowned experts in infertility treatment, specializing in pregnancy for difficult infertility cases and women 40+.

Internationally recognized for infertility treatment and research, CHR is known worldwide as the infertility center of last resort. One of the first IVF centers established in the U.S., the Center for Human Reproduction (CHR) offers all aspects of modern infertility treatment. Through extensive research and clinical efforts, CHR has developed special knowledge and expertise in treating diminished ovarian reserve, a classic finding in older women and also in younger women with prematurely aging ovaries. Our pioneering research into IVF with DHEA supplementation — a treatment that CHR studies have found can double the IVF pregnancy chances in women with diminished ovarian reserve — has been noted worldwide, and one third of all infertility centers now use the technique. CHR also offers one of the world’s largest and most diverse egg donor programs. Located in Manhattan, New York City (NYC), approximately half of our patients are local, with another half hailing from other states and abroad. We invite you to learn more about CHR’s clinical offerings, treatments, research, and educational activities by exploring our extensive website. Feel free to contact us with any questions!

Our Second Opinion Program is here provide extra guidance so that you can move forward with clarity and confidence. ...
04/17/2026

Our Second Opinion Program is here provide extra guidance so that you can move forward with clarity and confidence.

At CHR, we are exploring one of the most important questions in reproductive medicine: can we improve oocyte quality by ...
04/16/2026

At CHR, we are exploring one of the most important questions in reproductive medicine: can we improve oocyte quality by optimizing how follicles function at a cellular level?

Our IRB-approved Sirolimus Cycle Priming trial targets the mTOR pathway, a key regulator of cellular aging, metabolism, and oxidative stress. When dysregulated, this pathway may contribute to poor egg quality, even in women with normal ovarian reserve.

By using a short-term course of Sirolimus prior to stimulation, we aim to create a healthier follicular environment and improve embryo development outcomes.

This study is designed for patients who “look good on paper” but have struggled with poor IVF results, bringing precision, mechanism-based care to a complex clinical problem.

Thank you for sharing your experience and for trusting CHR! 🤍
04/14/2026

Thank you for sharing your experience and for trusting CHR! 🤍

04/10/2026

Thinking about egg freezing but don’t know where to start? Watch this video for a breakdown.

The biggest takeaway is that you have more control than you think. Save this for later & share it with a friend who’s been curious about fertility preservation!

We're hiring for international healthcare professionals! If you're interested, please send your resume and a brief intro...
04/09/2026

We're hiring for international healthcare professionals!

If you're interested, please send your resume and a brief introduction to: jtapper@thechr.com.

At CHR, we are pushing the boundaries of reproductive science to improve outcomes for patients with diminished ovarian r...
04/09/2026

At CHR, we are pushing the boundaries of reproductive science to improve outcomes for patients with diminished ovarian reserve (DOR).
Our newest IRB-approved clinical trial explores the role of G-CSF ovarian priming: a novel approach designed to optimize the ovarian environment before IVF stimulation begins.

Traditionally used to support the endometrium, G-CSF is now being studied for its potential effects on the o***y, including improving blood flow, supporting early follicle development, and reducing follicular loss. Our protocol applies a targeted luteal-phase regimen to enhance follicle recruitment ahead of the next cycle.

This is translational ART at its best - where emerging science meets real-world patient care.

The latest edition of The Voice for February/March has now been published! Featuring important news from our medical tea...
04/08/2026

The latest edition of The Voice for February/March has now been published! Featuring important news from our medical team, advancements in reproductive medicine, and engaging stories, there’s something that will appeal to everyone.

Visit the link in our bio to explore it today!

Our new blog post on the topic of Lactation Without Pregnancy is now live! Click the link in our bio to read about Dr. S...
04/07/2026

Our new blog post on the topic of Lactation Without Pregnancy is now live! Click the link in our bio to read about Dr. Sonia Gayete-Lafuente's insights.

Happy Easter from the CHR Team!
04/05/2026

Happy Easter from the CHR Team!

Join us for a CHR Grand Rounds with Alexander Tarakhovsky, MD on the topic of Suspended Animation and Organism Longevity...
04/03/2026

Join us for a CHR Grand Rounds with Alexander Tarakhovsky, MD on the topic of Suspended Animation and Organism Longevity. His research explores how epigenetic mechanisms shape immune cell signaling, virus–host interactions, and cellular longevity, and he has published extensively in Nature, Science, and Cell. He was the first to articulate the paradigm of epigenetic mimicry by pathogens, demonstrating how microbial factors co-opt host chromatin regulation to subvert immunity.

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🗓 Date: May 5, 2026
⏰ Time: 7pm ET⁠
📍 In person & virtual⁠
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🔗 Registration link in bio⁠
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04/03/2026

You don’t need to have it all figured out, but you can stay informed about your reproductive health and your fertility options. Egg freezing isn’t about pressure, it's about have the flexibility to decide on your own timelines.

Part 2 coming next: what the egg freezing process looks like.

At CHR, we’re proud to launch our IRB-approved clinical trial on hCG ovarian priming, designed to improve IVF outcomes i...
04/02/2026

At CHR, we’re proud to launch our IRB-approved clinical trial on hCG ovarian priming, designed to improve IVF outcomes in women with diminished ovarian reserve (DOR). ⁠
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Traditional IVF focuses on later-stage follicle growth. Our approach goes earlier: targeting preantral follicle development through low-dose high priming from four weeks before stimulation. By activating LH receptors at this critical stage, we aim to recruit more follicles and increase the number of mature eggs available for fertilization. ⁠
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This is translational ART in action - evidence-based, innovative, and already integrated into patient care. ⁠
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Address

21 E. 69th Street
New York, NY
10021

Opening Hours

Monday 8:30am - 5pm
Tuesday 8:30am - 5pm
Wednesday 8:30am - 5pm
Thursday 8:30am - 5pm
Friday 8:30am - 5pm
Saturday 8:30am - 12pm
Sunday 8:30am - 12pm

Website

https://www.foundati

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