American Federation for Aging Research

10/07/2025

TWO WEEKS AWAY: Join AFAR President Thomas A. Rando, MD, PhD, AFAR Scholar-in-Residence Raiany Romanni, PhD, and The Boston Globe's Brian Bergstein in our free “The Potential of Geroscience: from Economic Gains to Social Returns and Ethical Concerns” on Tuesday October 21st, at 4pm ET.
Learn more and RSVP here: https://ow.ly/e8mS50X3VUX

10/03/2025

Recording now available from the Academy for Health & Lifespan Research and AFAR’s recent , “The State of Gerotherapeutics: Next Gen Interventions to Extend Healthy Living” featuring AFAR board member and multiple grantee Nir Barzilai, MD, of the Academy for Health & Lifespan Research; AFAR awardee Rafael de Cabo, PhD, of the National Institute on Aging - NIH; AFAR board member Sara Espinoza, MD, MSc, of Cedars-Sinai Medical Center; AFAR grantee Kristen Fortney, PhD, of BioAGE Labs; Carolina Solis Herrera, MD, of UT UT Health San Antonio; and moderator Dana G. Smith of The New York Times.
Watch the recording now: https://vimeo.com/1121256811?fl=pl&fe=sh

10/02/2025

Later this month, join AFAR for a free webinar on Tuesday October 21st at 4pm ET, on the economic gains, health rewards, and social returns that geroscience can generate. Featuring AFAR President Thomas A. Rando, MD, PhD, and AFAR Scholar-in-Residence Raiany Romanni, PhD, in conversation with The The Boston Globe's Brian Bergstein.
Learn more and RSVP here: https://ow.ly/e8mS50X3VUX

10/02/2025

Back to School: Basics in Biology with AFAR 📓
The Hallmarks of Aging Pt. III

In the final part of our series, we’re sharing four more hallmarks that help explain how our bodies change over time:

- Genomic Instability
- Telomere Attrition
- Chronic Inflammation
- Dysbiosis

Science is always evolving, and researchers continue to discover new hallmarks that help us better understand aging. Thank you for joining us for our Back to School crash course on the Hallmarks of Aging for !

Watch the animation and explore more here: https://www.afar.org/hallmarksofaging #3

10/01/2025

Recording now available from the Academy for Health & Lifespan Research and AFAR’s recent webinar, “The State of Gerotherapeutics: Next Gen Interventions to Extend Healthy Living” featuring AFAR board member and multiple grantee Nir Barzilai, MD, of the Academy for Health & Lifespan Research; AFAR awardee Rafael de Cabo, PhD, of the National Institute on Aging - NIH; AFAR board member Sara Espinoza, MD, MSc, of Cedars-Sinai Medical Center; AFAR grantee Kristen Fortney, PhD, of BioAGE Labs; Carolina Solis Herrera, MD, of UT Health San Antonio; and moderator Dana G. Smith of The New York Times.
Watch the recording now: https://vimeo.com/1121256811?fl=pl&fe=sh

09/25/2025

Back to School: Basics in Biology with AFAR 📓
The Hallmarks of Aging Pt. II

In Part I, we explored some of the biological processes that drive aging. Now, we’re back with four more hallmarks that shape how our bodies change over time:

- Mitochondrial Dysfunction
- Cellular Senescence
- Stem Cell Exhaustion
- Altered Intercellular Communication

Watch our video below to see these hallmarks in action, and dive deeper by visiting: https://www.afar.org/hallmarksofaging #2

09/22/2025

LAST CHANCE to RSVP for today’s free webinar with the Academy for Health & Lifespan Research on the current state of existing and emerging drug interventions to extend healthspan. Moderator Dana G. Smith, of The New York Times, will be joined by AFAR board member and multiple grantee Nir Barzilai, MD, of the Academy for Health & Lifespan Research; AFAR awardee Rafael de Cabo, PhD, of the National Institute on Aging - NIH; AFAR board member Sara Espinoza, MD, MSc, of Cedars-Sinai Medical Center; AFAR grantee Kristen Fortney, PhD, of BioAGE Labs; and Carolina Solis Herrera, MD, of UT Health San Antonio.
Learn more and RSVP here: https://buff.ly/3tr4wv5

09/19/2025

Next Monday, September 22nd from 3-4pm ET, join AFAR and the Academy for Health & Lifespan Research for a free on the current state of existing and emerging drug interventions to extend healthspan. Moderator Dana G. Smith, of The New York Times, will be joined by AFAR board member and multiple grantee Nir Barzilai, MD, of the Academy for Health & Lifespan Research; AFAR awardee Rafael de Cabo, PhD, of the National Institute on Aging - NIH; AFAR board member Sara Espinoza, MD, MSc, of Cedars-Sinai Medical Center; AFAR grantee Kristen Fortney, PhD, of BioAGE Labs; and Carolina Solis Herrera, MD, of UT UT Health San Antonio.
Learn more and RSVP here: https://buff.ly/3tr4wv5

09/18/2025

Drawing on her research with SLG2 inhibitors to extend healthspan, Carolina Solis Herrera, MD, of UT Health San Antonio, will be in conversation Dana G. Smith, of The New York Times at our Sept 22 webinar on the State of Gerotherapeutics. They’ll be joined by an impressive mix of experts from the academic, biotech, and federal sectors who are driving interventions to help us live healthier, longer.

Presented with the Academy for Health & Lifespan Research, join us on 9/22 from 3-4pm ET.

Learn more and RSVP here: https://buff.ly/3tr4wv5

09/18/2025

Back to School: Basics in Biology with AFAR📓
The Hallmarks of Aging Pt. I

September is , making it the perfect time to go back to the basics of how and why our bodies age.

Over the past decades, the aging research community has identified cellular processes known as the Hallmarks of Aging, the biological machinery that drive aging in our bodies. Think of them as the fundamental building blocks of aging, interconnected processes that, when disrupted, can contribute to age-related diseases, and when supported, may help us stay healthier for longer.

As science advances, our understanding of these hallmarks continues to evolve and expand, and new additions are still being explored. Together, they provide a roadmap for researchers developing therapies to help us live healthier, longer.

In this short video, we introduce three hallmarks:
- Epigenetic Alterations
- Loss of Proteostasis and Disabled Macroautophagy
- Deregulated Nutrient Sensing

Watch the video below to learn, and explore more by visiting: https://www.afar.org/hallmarksofaging #1

09/17/2025

Looking forward to insights AFAR grantee Kristen Fortney, PhD, and CEO and Co-Founder of BioAGE Labs will share in conversation Dana G. Smith, of The New York Times at our Sept 22 webinar on the State of Gerotherapeutics. They’ll be joined by an impressive mix of experts from the academic, biotech, and federal sectors who are driving interventions to help us live healthier, longer.

Presented with the Academy for Health & Lifespan Research, join us on 9/22 from 3-4pm ET.

Learn more and RSVP here: https://buff.ly/3tr4wv5

09/16/2025

The New York Times recently featured AFAR-affiliated experts Thomas M. Gill, MD, Donovan T. Maust, MD, and Michael Steinman, MD, in an article exploring factors of the increase in fall‑related deaths in older Americans.
Read here:

Some researchers suspect that rising prescription drug use may explain a disturbing trend.