Columbia University Medical Center - Center for Radiological Research

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Columbia University Medical Center - Center for Radiological Research

To provide an unbiased, comprehensive, independent source of scientific information on radiation exp

The mission of the Center for Radiological Research (CRR) is 1) to foster a multi disciplinary approach towards understanding the biological and human health consequences of ionizing radiation exposure 2) to train the next generation of radiobiologists and 3) to provide an unbiased, comprehensive, independent source of scientific information on radiation exposure for government, elected officials, non-profit institutions and private entities to enable them to make informed policy decisions.

10/11/2023

It's our annual Research Retreat. Keeping the clinic and the laboratory working together.

28/03/2023

The CRR will be hosting the First International Congress on Far-UVC Science and Technology (ICFUST) on June 14th-16th, 2023.

This new conference bringing together the Far-UVC community to discuss basic science to applications in real world settings.

04/11/2022

Dr. Hei presenting at our annual CRR/ Radiation Oncology Research Retreat. Cross pollinating the research labs with the clinic and clinic to the labs.

06/10/2020

The Announcement for Pilot Projects for the Centers for Medical Countermeasures against Radiation Consortium (CMCRC), of which the CRR is a part, has come out for 2020. The application deadline is Dec. 21, 2020 with anticipated start date of May 1, 2021.

https://cmcrcniaid.org/content/instructions

NIAID/NIH Centers for Medical Counter Measures Against Radiation (CMCR) Program Call for Pilot Project Applications The Centers for Medical Countermeasures against Radiation (CMCR) https://grants.nih.gov/grants/guide/rfa-files/rfa-ai-19-012.html are now accepting applications for pilot projects focu...

05/10/2020

Our director David Brenner conquered one of the steep hills of NJ (Eisenhower Drive) 8 times yesterday, to raise funds for in this year’s Ride to End Cancer.

For more information about the Velocity Ride campaign check out https://www.velocityride.org/

27/08/2020

25/07/2020

Our Director, Dr. David Brenner Has given another TED talk. This on the power of Far-UVC light to combat the coronavirus, COVID-19.

Far-UVC light is a type of ultraviolet light that kills microbes and viruses and, crucially, seems to be safe to use around humans. Radiation scientist David Brenner describes how we could use this light to stop the spread of SARS-CoV-2, the virus responsible for COVID-19, in hospitals, nursing home...

24/06/2020

Our Far-UVC team, head by Dr. David Brenner, with Drs Manuela Buonanno, David Welch and Igor Shuryak has a new publication out in Scientific Reports!

'Far-UVC light (222 nm) efficiently and safely inactivates airborne human coronaviruses'

Scientific Reports volume 10, Article number: 10285 (2020)

This article looks at the efficiency and safety for using Far-UVC against human coronaviruses. Results look positive for the use of Far-UVC against SARS-Cov-2 based on this work. More testing to come but a big step forward.

https://www.nature.com/articles/s41598-020-67211-2

A direct approach to limit airborne viral transmissions is to inactivate them within a short time of their production. Germicidal ultraviolet light, typically at 254 nm, is effective in this context but, used directly, can be a health hazard to skin and eyes. By contrast, far-UVC light (207–222....

14/05/2020

We had such a successful first round response to help our Far-UVC work so we stretched our goal to $75,000. We are just about $3500 short of reaching that stretch goal. Please help us reach our goal!

These funds help us continue the development of our Far-UVC lights for use in everyday applications. The initial goal has helped fund testing against COVID-19 in the lab (results look good and are coming out soon) and starting collaborations with our clinical staff looking at application in controlled waiting and treatment areas.

We hope this work will lead to FDA approval and make this technology available for public use.

https://crowdfund.columbia.edu/pages/cuimc-research

212.851.9942 • 855.317.9500 The information collected via the social sharing wizard is not stored, and will not be used by Columbia University or sold or shared with any third-party organizations.

26/03/2020

Hi everyone! We at the CRR hope you are all well.

We are continuing to work through this unique situation on our UV sterilizer projects. We hope to be closer to deployment of these systems to help going forward.

On that note, we are working harder in several unanticipated directions. These new directions are incurring expenses beyond our budgeting for the year. If you would like to help, Columbia Development has set up a Crowdfunding page where you can donate. Thanks!

https://crowdfund.columbia.edu/pages/cuimc-research

212.851.9942 • 855.317.9500 The information collected via the social sharing wizard is not stored, and will not be used by Columbia University or sold or shared with any third-party organizations.

15/11/2019

Our Radiation Oncology Chairwoman Lisa Kachnic opening our 5th Annual Radiation Oncology Research Retreat.

The Retreat is our traditional opportunity to bring our lab and clinical researchers together to discuss progress, developed new opportunities, and new collaborations so we can work together to improve both our research and clinical care.

09/01/2019

The CRR has 4 open positions! 2 Postdocs and 2 Technician B. https://www.crr.columbia.edu/about-us/careers-jobs

20/11/2018

How about a shot of ultraviolet light instead of a flu shot? With seasonal vaccines often proving ineffective, researchers work on germ-killing lamps and a ‘universal vaccine’ to keep the virus at bay.

12/11/2018

Here are your personal belongings, a free MetroCard . . . and your total accumulated radiation count. Enjoy your freedom. The city Health Department has issued new regulations that would allow inma…

09/11/2018

The CUIMC Department of Radiation Oncology will host its 4th annual research retreat on November 16th. https://www.crr.columbia.edu/news/cuimc-dept-radiation-oncology-hosts-annual-research-retreat

The CUIMC Dept. of Radiation Oncology will host their 4th annual research retreat on Friday, Nov. 16th.

01/10/2018

BREAKING NEWS
The Nobel Assembly at Karolinska Institutet has today decided to award the 2018 Nobel Prize in Physiology or Medicine jointly to James P. Allison and Tasuku Honjo “for their discovery of cancer therapy by inhibition of negative immune regulation.”

Cancer kills millions of people every year and is one of humanity’s greatest health challenges. By stimulating the inherent ability of our immune system to attack tumour cells this year’s Nobel Laureates have established an entirely new principle for cancer therapy.

James P. Allison studied a known protein that functions as a brake on the immune system. He realised the potential of releasing the brake and thereby unleashing our immune cells to attack tumours. He then developed this concept into a brand new approach for treating patients.

In parallel, Tasuku Honjo discovered a protein on immune cells and, after careful exploration of its function, eventually revealed that it also operates as a brake, but with a different mechanism of action. Therapies based on his discovery proved to be strikingly effective in the fight against cancer.

Allison and Honjo showed how different strategies for inhibiting the brakes on the immune system can be used in the treatment of cancer. The seminal discoveries by the two laureates constitute a landmark in our fight against cancer.

Learn more: https://bit.ly/2OpzIIS

30/08/2018

Columbia researchers are developing an optical fiber system that uses a type of UV light to sterilize areas around skin-penetrating medical devices.

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What We Do

Mission

Staff

The Center's staff includes professionals from diverse fields including molecular biology, cell biology, radiation physics, computational physics, engineering, radiation oncology and public health.

Research

The Center for Radiological Research (CRR) is a worldwide leader in unraveling the biological and molecular mechanisms underlying radiation effects in cells, tissues, organ systems and living organisms and how radiation exposure affects human health.

Teaching

For more than 75 years, the Center has been at the forefront of training undergraduates, medical and graduate students in radiobiology, health physics and medical physics. The faculty instructs medical residents in Radiology and Radiation Oncology in the Columbia University School of Physicians & Surgeons and offers a citywide course for Radiology residents as part of their training.

International Collaborations

Our faculty interact with and have research collaborations with a wide range of international and national educational institutions, research laboratories, academic leaders in radiological sciences, non-profit organizations, advisory groups and governmental agencies and have served as consultants and advisors for the International Commission on Radiological Protection (ICRP), the National Council on Radiation Protection & Measurements (NCRP), Nuclear Regulatory Commission (NRC) and the International Atomic Energy Agency (IAEA).

The Center is a member of the International Consortium for Medical Care of Hibakusha (A-bomb survivors) and Radiation Life Science organized by the Graduate School of Biomedical Sciences of Nagasaki University, Japan where it joins other international institutions to promote international collaboration in radiation research and graduate education.

National Security

The National Institutes of Health (NIH) funded Center for High Throughput Minimally-Invasive Radiation Biodosimetry and the Biomedical Advanced Research and Development Authority (BARDA), funded research efforts at the Center have led to development of novel assays and rapid screening techniques to enable accurate determination of individual radiation exposures in large numbers of potentially exposed persons.

The CRR has been at the forefront of efforts to evaluate individual risk from radiation exposure and provide advice and guidance to appropriate regulatory and governmental officials.