02/26/2026
The 0.18 fluocinolone acetonide intravitreal implant (FAi) successfully improved visual acuity, reduced macular edema (ME), and attenuated choroidal thickening in patients with non-infectious uveitis (NIU)-associated ME during a 12-month retrospective study.
The first FAi received approval from the US Food and Drug Administration (FDA) in October of 2018 for the treatment of chronic non-infectious intermediate, posterior, or panuveitis with active inflammation. The implant is designed to release medication over 3 years; the drug is housed within a nonbioerodible material.
A recent study highlights the efficacy of the FAi implant in patients with NIU-related macular edema, improving BCVA and reducing choroidal thickness.