American Journal of Neuroradiology

American Journal of Neuroradiology The Journal of Diagnostic and Interventional Neuroradiology (Official Journal: ASNR, ASFNR, ASHNR, AS
(229)

Published by the American Society of Neuroradiology (ASNR), the American Journal of Neuroradiology (AJNR) publishes original articles pertaining to the clinical imaging, therapy, and basic science of the central and peripheral nervous system. In a typical year, AJNR publishes more than 350 fully reviewed Original Research papers, Review Articles, and Technical Notes. Subject matter covers the spectrum of diagnostic and functional imaging of the brain, head, neck, spine, and organs of special sense, including: aging and degenerative diseases; anatomy; the cervicothoracic junction; contrast media; experimental studies; functional imaging; iatrogenic disorders; imaging techniques and technology (including all advanced imaging modalities); inflammatory diseases; interventional techniques and related technology; the larynx and lymphatics; molecular imaging; the nasopharynx and skull base; neoplastic diseases; the nose and paranasal sinuses; oral and dental imaging; ophthalmologic and otorhinolaryngologic imaging; pediatric ENT radiology; pediatric neuroradiology and congenital malformations; the phakomatoses; radionuclide imaging; the salivary glands; seizure disorders; cancer, stroke, and cerebrovascular diseases; the temporal bone; and tissue characterization and trauma. AJNR is abstracted and/or indexed by PubMed/Medline, BIOSIS Previews, Current Contents (Clinical Medicine and Life Sciences), EMBASE, Google Scholar, HighWire Press, Q-Sensei, RefSeek, Science Citation Index, and SCI Expanded. Twelve issues per year, peer-reviewed, approximately 200 pages per issue. OFFICIAL JOURNAL: American Society of Neuroradiology, American Society of Functional Neuroradiology, American Society of Head and Neck Radiology, American Society of Pediatric Neuroradiology, American Society of Spine Radiology

Check our Fellows’ Journal Club choice for March: ‘Risk Factors for Spinal Cord Compression on MRI in Oncology: Enhancin...
03/16/2026

Check our Fellows’ Journal Club choice for March: ‘Risk Factors for Spinal Cord Compression on MRI in Oncology: Enhancing Diagnostic Yield’

Total spine MRI is commonly used to assess epidural spinal cord compression (ESCC) in patients with cancer, but this retrospective study found a relatively low diagnostic yield, with ESCC detected in only 6% of 300 examinations. Higher risk was associated with advanced disease stage, prior spinal treatments, recent chemotherapy, and the presence of spinal bone metastases on recent body CT. Notably, no ESCC cases occurred in patients without bone metastases or with disease stages below IV, and symptoms did not reliably predict ESCC. Refining imaging criteria may improve diagnostic efficiency in oncology patients.
https://www.ajnr.org/content/47/3/837

03/13/2026

AJNR Junior Editorial Board Call for applications!

Apply by March 16, 2026!

https://www.ajnr.org/content/ajnr-junior-editorial-board

Interested in gaining in-depth experience with editorial and peer review processes?

Goals:
Improve peer review training and experience
Offer a broad understanding of the publishing process
Provide mentorship and networking opportunities
Provide publication opportunities
Share cutting-edge knowledge in neuroradiology

Check one of our Fellows’ Journal Club choicefor the month ‘Unilateral Primary Angiitis of the Central Nervous System: A...
03/12/2026

Check one of our Fellows’ Journal Club choice
for the month ‘Unilateral Primary Angiitis of the Central Nervous System: A Rare and Underrecognized Entity’
Unilateral primary angiitis of the central nervous system is a rare subtype of vasculitis involving the brain, spinal cord, or leptomeninges. Because of its nonspecific imaging features and variable presentations, including masslike lesions, infarcts, or hemorrhages, this unilateral form often mimics tumors, demyelinating disease, or chronic encephalitis. Most cases show lymphocytic small- to medium-vessel vasculitis, and diagnosis is challenging, especially when angiography is negative. Early recognition is crucial, as prompt immunosuppressive treatment can prevent misdiagnosis and irreversible neurologic injury.

https://www.ajnr.org/content/47/3/589

Check our Fellows’ Journal club choice of the month: ‘Prolonged Venous Transit Is Associated with Unfavorable Functional...
03/07/2026

Check our Fellows’ Journal club choice of the month: ‘Prolonged Venous Transit Is Associated with Unfavorable Functional Outcomes in Large-Core Stroke’

Large-core acute ischemic stroke due to large vessel occlusion carries a high risk of poor outcomes, and prolonged venous transit (PVT) on CTP has emerged as a possible prognostic marker. In this retrospective cohort of 100 patients meeting large-core criteria, PVT was present in 41% and was independently associated with unfavorable 90‑day outcomes. Even after accounting for penumbra size and core volume, PVT significantly increased the odds of severe disability or death.

https://www.ajnr.org/content/47/3/596/tab-figures-data

AJNR Junior Editorial Board Call for applications!Interested in gaining in-depth experience with editorial and peer revi...
02/28/2026

AJNR Junior Editorial Board Call for applications!

Interested in gaining in-depth experience with editorial and peer review processes?

Goals:
Improve peer review training and experience
Offer a broad understanding of the publishing process
Provide mentorship and networking opportunities
Provide publication opportunities
Share cutting-edge knowledge in neuroradiology

Apply by March 16, 2026!

https://www.ajnr.org/content/ajnr-junior-editorial-board

Check one of our Editor’s choice for the month:‘The Impact of Different CT Perfusion Software on Patient Stratification ...
02/26/2026

Check one of our Editor’s choice for the month:
‘The Impact of Different CT Perfusion Software on Patient Stratification Strategies in Ischemic Stroke’

This study compared 2 commercially available CT perfusion software packages to assess differences in ischemic core estimation and their impact on eligibility for endovascular treatment. Among 109 patients with stroke, the software programs produced significantly different core volumes across all tested thresholds, which in turn led to meaningful discrepancies in EVT stratification—particularly when applying DAWN criteria. Although using more conservative thresholds reduced these differences, clinicians should be aware that software choice may directly influence treatment decisions.

https://www.ajnr.org/content/47/2/329

Check our last Editor’s choice for the month: ‘Brain Plasticity Induced by MR-Guided Focused Ultrasound Correlates with ...
02/25/2026

Check our last Editor’s choice for the month: ‘Brain Plasticity Induced by MR-Guided Focused Ultrasound Correlates with Tremor Improvement in Essential Tremor: A Prospective Cohort Study’

The authors of this study evaluated long‑term brain structural changes in 26 patients with essential tremor following MR‑guided focused ultrasound, using MRI both before treatment and 1 year afterward. Patients showed significant decreases in gray matter volume in the left postcentral gyrus, left thalamus, and right superior temporal gyrus, along with GMV increases in several cerebellar regions. Additional region‑based analyses identified GMV reductions in the globus pallidus and specific thalamic nuclei. GMV changes in multiple clusters were significantly correlated with tremor improvement, suggesting that MRgFUS induces neuroplastic remodeling in both adjacent and remote brain regions.

https://www.ajnr.org/content/47/2/409

Check one of our Editor’s choice for the month: ‘Maximizing the Conspicuity of CSF-Venous Fistulas on CT Myelography: As...
02/24/2026

Check one of our Editor’s choice for the month: ‘Maximizing the Conspicuity of CSF-Venous Fistulas on CT Myelography: Assessment of Contrast Density and Timing Effects’

This study evaluated how timing of image acquisition and contrast density in the subarachnoid space affect the visualization of CSF‑venous fistulas on CT myelography. Both higher contrast density and shorter acquisition time significantly improved CVF conspicuity, with contrast density having a 4‑fold greater influence than timing. An increase of 100 HU in attenuation corresponded to a 14.3% greater likelihood of fistula detection, with an optimal density threshold of 836 HU. These findings suggest prioritizing maximizing contrast density—potentially through positioning strategies—to enhance CVF detection more effectively than timing adjustments alone.

https://www.ajnr.org/content/47/2/537

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