01/16/2026
OU Health is home to bold, collaborative science, and new research from across our campus is offering exciting insights for people living with Type 2 diabetes. A recent review led by Elizabeth Wellberg, Ph.D., at the OU College of Medicine looked closely at GLP-1 medications like semaglutide and liraglutide. These drugs have already transformed diabetes care, and now researchers are uncovering even more potential benefits.
This kind of forward-thinking research is happening every day across the OU Health campus, driven by our shared commitment to improving the lives of all Oklahomans. It is an exciting glimpse into how today’s therapies may shape tomorrow’s breakthroughs.
At OU Health Stephenson Cancer Center, we want to keep you informed about research that could impact your health. A recent review by Elizabeth Wellberg, Ph.D., a researcher and assistant professor of pathology at the OU College of Medicine, explored GLP-1 medications like semaglutide and liraglutide, which are commonly used for diabetes and weight loss, and examined their possible connection to cancer.
GLP-1 drugs help control blood sugar and appetite. Encouragingly, studies show these medications do not increase cancer risk. In fact, Dr. Wellberg shared, “We found evidence that people using GLP-1 drugs do not experience higher overall cancer rates compared with non-users. Some studies even reported lower incidence of cancer, including colorectal, liver, prostate and endometrial cancers.” Animal research also suggests these drugs might directly slow tumor growth, even in the absence of weight loss.
Researchers are also exploring whether GLP-1 medications boost the immune system’s ability to detect and eliminate abnormal cells. As Dr. Wellberg explained, “It may be that GLP-1s create a heightened surveillance in immune cells that makes them better at getting rid of damaged cells before they turn cancerous.” While these findings are promising, more long-term clinical trials are needed to understand how GLP-1 medications could be used to prevent or treat cancer.
Stephenson Cancer Center is proud to be part of this trailblazing work as the academic healthcare partner of The University of Oklahoma, advancing shared missions of teaching, research and clinical care.