02/14/2021
Monoclonal Antibodies for COVID and You
Though most patients and the press are understandably focused on the availability of COVID vaccines one should be aware of the potential role of Monoclonal Antibodies. Monoclonal Antibodies are the ONLY treatment for early/mild COVID infection that has been shown to prevent hospitalization or worse. The data show that for every 10-20 COVID + patients given monoclonal antibodies one hospitalization or worse can be prevented. So far over 3000 infusions have been given to Maryland patients who meet criteria which has likely prevented as many as 300 hospitalizations.
In the state of Maryland there are presently about 2 million people who are eligible to receive the COVID vaccine for prevention with the state presently receiving just 72 thousand doses per week to distribute. On the other hand, there is a SURPLUS of monoclonal antibodies that have been provided to the state by the federal government which are sitting on shelves unused. So who is eligible to receive monoclonal antibodies for Covid? First you must have a positive Covid test either rapid antigen or PCR, second you must be considered “high risk’, third you must have “mild disease” which means that if you are sick enough to be hospitalized you likely won’t get the medication, and finally no more than 10 days have elapsed from the onset of symptoms until the outpatient infusion takes place.
“High Risk” includes being on immunosuppressants including chemotherapy, overweight (BMI greater than or equal to 35), diabetes, age of 65 or greater, chronic kidney disease, and for those 55 or over “cardiovascular disease” which includes coronary disease, peripheral vascular disease or just hypertension, “lung disease” which includes COPD. This list includes most of our patients! Other eligible include those ages 12-17 with chronic illness including asthma.
“Mild Disease” can mean just about anything including sore throat, nasal congestion, body aches, fever, cough, nausea, vomiting, diarrhea.
The State of Maryland has been very active in promoting the establishment of outpatient infusion centers dedicating to giving monoclonal antibodies which requires an IV and takes about an hour; presently there are about a dozen such centers throughout the state with more coming online every week. Treatment requires a positive COVID test as noted above, “mild symptoms” as noted, “high risk” as noted PLUS TREATMENT GIVEN WITHIN THE 10 DAY PERIOD from onset of symptoms. Additionally a referral by a physician is required.
Anecdotally we have arranged for about a half dozen of our patients to receive the treatment and we have see some dramatic and often rapid improvement of symptoms with to date no one requiring hospitalization and no reported side effects.
BOTTOM LINE; if you have even minor symptoms go out and get COVID tested and if you meet criteria we can quickly arrange for you to have a local outpatient infusion. DON’T wait a week w lingering symptoms to call us; there may not be enough time to have you tested and arrange for this potentially life saving treatment.