04/02/2026
Here’s why ⬇️
Estrogen directly supports mitochondrial function — the process by which your cells convert food into usable energy.
As estrogen shifts in perimenopause, so does your cellular energy production.
Not because you’re eating less or moving less.
Because the engine itself is running with fewer resources.
The B vitamins, magnesium, CoQ10, and carnitine your mitochondria depend on?
Most women are subtly depleted in several of them — not enough to flag on a standard panel, but enough that the system is working harder than it should for the output it’s generating.
That’s why the 3pm crash doesn’t respond to more protein. That’s why the fatigue doesn’t respond to more sleep.
It’s a substrate problem nobody’s talking about.
This week’s Substack breaks down the full picture — what metabolism actually is, the nutrients that run it, and how to actually test for what’s happening at the cellular level.
Comment SUBSTACK and I’ll send you the link.