Stanford PMHW

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Stanford PMH is a research center working to connect brain function and mental health, and to translate those discoveries into ways to detect mental disorders earlier, identify optimal treatments faster and ultimately help more patients.

đź§  Precision Psychiatry in Action đź§ Thrilled to share our new paper in Nature Mental Health! We show that targeting a spec...
10/13/2025

đź§  Precision Psychiatry in Action đź§ 

Thrilled to share our new paper in Nature Mental Health! We show that targeting a specific brain mechanism can alleviate the cognitive biotype of depression.

Depression is still treated mostly by trial and error. Our goal is to change that with precision approaches.

Using fMRI, we identified individuals with dysfunction in the cognitive control circuit - the brain network for focus, decision-making, and self-control. We then tested whether immediate release guanfacine, a treatment that strengthens this circuit, reduces depressive symptoms.

✨ The results: ✨
• Treatment restored brain circuit function and cognitive performance
• 76.5% clinical response
• 84.6% remission among responders

This is one of the first demonstrations that directly targeting a brain circuit can drive remission in depression - a proof-of-concept for precision psychiatry.

Grateful to our incredible multidisciplinary team, our participants, and Stanford Medicine partners who made this work possible.

đź”— Full paper here: https://lnkd.in/gmMQyM36


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✨ The recordings are here! ✨ Thank you to everyone who joined us for the 5th Annual Symposium of the Stanford Center for...
10/10/2025

✨ The recordings are here! ✨

Thank you to everyone who joined us for the 5th Annual Symposium of the Stanford Center for Precision Mental Health on Sept. 26. The day was an incredible success—bringing together Stanford faculty, postdocs, staff, students, affiliates, global experts, and industry leaders to explore the future of psychiatry, neuroscience, and AI. Together, we are building the future of precision mental health.

🎥 Now you can relive the energy and insights or experience them for the first time. The recordings are now available on our YouTube channel.

👉 Watch the recordings here: https://www.youtube.com/playlist?list=PLLAjftNarQeLMxt2baK75tC0SAg14v6Ee

👏Poster Winner Spotlight!👏 We are proud to congratulate Alexander Palmer, BS, one of our symposium poster award winners,...
10/04/2025

👏Poster Winner Spotlight!👏 We are proud to congratulate Alexander Palmer, BS, one of our symposium poster award winners, for his presentation on "Neurophysiological correlates of psychedelic experience are retained during general anesthesia".
đź’ˇThis bold and thought-provoking research challenges assumptions about the role of consciousness in psychedelic brain states. It opens exciting new directions for understanding the mechanisms of psychedelic action. It was a standout contribution to our event. Congratulations!

🌟Poster Winner Spotlight! 🌟Congratulations to Dan McCalley, PhD, a winner of our symposium poster session at  ! 💡His pos...
10/03/2025

🌟Poster Winner Spotlight! 🌟Congratulations to Dan McCalley, PhD, a winner of our symposium poster session at ! 💡His poster, "A step toward precision Transcranial Magnetic Stimulation for Alcohol Use Disorder: an fMRI-based, data-driven approach to guide future TMS trials for AUD," was recognized for its scientific rigor and innovation.
This work exemplifies how advanced neuroimaging and data-driven modeling can inform targeted, circuit-level interventions in psychiatry.

👏Poster Winner Spotlight!👏 We are delighted to announce one of the winners of our symposium poster session at Stanford: ...
10/02/2025

👏Poster Winner Spotlight!👏 We are delighted to announce one of the winners of our symposium poster session at Stanford: Jeesung Ahn, PhD, for her work on "Developing Clinically Interpretable Neuroimaging Biotypes in Psychiatry".
💡Dr. Ahn's research exemplifies the innovative spirit of our symposium —Bridging Psychiatry, Neuroscience & AI —by advancing efforts to define data-driven brain biotypes that are both scientifically rigorous and clinically meaningful. Congratulations on this outstanding achievement!

✨ Celebrating Our Visionary Leaders, Speakers and Panel Chairs! ✨We are deeply grateful to the visionary leaders, speake...
10/02/2025

✨ Celebrating Our Visionary Leaders, Speakers and Panel Chairs! ✨
We are deeply grateful to the visionary leaders, speakers and panel chairs who made our 5th Annual Precision Mental Health Symposium at Stanford such a resounding success.
đź’ˇYour insights and leadership created a wave of energy and inspiration that is shaping the future of precision mental health. The discussions you led not only advanced the science but also highlighted the impact these innovations can have for patients and communities worldwide.
The thought, care, and commitment you brought to every session made the day extraordinary - thank you!
We are deeply grateful to all of our speakers who made the day extraordinary — with special thanks to , David Entwistle, Olu Ajilore, Eleni Linos, Adam Gazzaley, Alex Leow, Jun Ma, Kilian Pohl, Ehsan Adeli, Jonathan Chen, Tina Hernandez-Boussard, Carolyn Rodriguez, Teddy Akiki, Eric van Staalduinen, Nolan Williams, Tom Insel, Bill Martin, Anna Gatti, Brandon Staglin, and Rebecca Cooney, for their remarkable contributions.

Can neural circuits guide treatment selection in depression?Join us at the Stanford Precision Mental Health Symposium an...
07/31/2025

Can neural circuits guide treatment selection in depression?

Join us at the Stanford Precision Mental Health Symposium and discover how fMRI and computational models are changing the way we diagnose and intervene.

This is an in-person event that takes place at Stanford on Friday, September 26th, 2025.

Save your spot today at https://www.stanfordpmhw.com/2025-pmhw-symposium

Earn CME credits and hear from an exciting line up of speakers. As always, registration is FREE!

What’s next in evidence-based, brain-informed mental health care?Join us at the Stanford Precision Mental Health Symposi...
07/19/2025

What’s next in evidence-based, brain-informed mental health care?
Join us at the Stanford Precision Mental Health Symposium and engage with experts translating neuroscience into tools for everyday clinical practice.
Registration is open! Join us at Stanford for the 5th Annual Precision Mental Health Symposium on Friday, Sept 26, 2025.
This year’s theme: Bridging Psychiatry, Neuroscience & AI
Explore the future of mental health care with leading scientists, clinicians & innovators.
Stanford LKSC | 8:30 AM – 6:00 PM
Register: www.med.stanford.edu/pmhw/2025-symposium
View full CME information and disclosure summary at https://stanford.cloud-cme.com/2025precisionmentalhealth.

Please join us in welcoming Ellie Beam, MD/PhD, our newest T32 fellow!Ellie’s innovative research blends psychoanalysis,...
07/03/2025

Please join us in welcoming Ellie Beam, MD/PhD, our newest T32 fellow!

Ellie’s innovative research blends psychoanalysis, biology, and AI to study how speech patterns reflect different depression biotypes —and predict who might benefit from treatments like MDMA-assisted therapy or TMS.
We’re honored to support her work at the Center for Precision Mental Health. Welcome, Ellie!

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đź§  Join us for the 5th Annual Stanford Precision Mental Health Symposium on Sept 26, 2025!Bridging Psychiatry, Neuroscien...
04/25/2025

đź§  Join us for the 5th Annual Stanford Precision Mental Health Symposium on Sept 26, 2025!

Bridging Psychiatry, Neuroscience and AI

Explore the future of mental health with leading experts in science, tech, and care innovation.

📍 In-person at Stanford University
🔬Discover cutting-edge research
đź’¬ Engage with thought leaders
🌱Network with future collaborators
🎓Learn how precision approaches are transforming diagnosis & treatment

Don’t miss this full-day event at the intersection of science, technology, and clinical innovation.

🔗 Register now: https://med.stanford.edu/pmhw/2025-symposium…

Check out our most recent work led by  highlighting the precision of scalp-based Beam/F3 targeting used to deliver   to ...
04/24/2025

Check out our most recent work led by highlighting the precision of scalp-based Beam/F3 targeting used to deliver to veterans with treatment-resistant depression at four VA hospitals. Personalized models of TMS electric fields revealed that engagement of the sgACC on multiple metrics was associated with depression symptom reduction. 👉https://doi.org/10.1016/j.brs.2025.04.003

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Join us in congratulating Teddy Akiki, MD on his promotion to Assistant Professor! 🎉 As a physician-scientist, Dr. Akiki...
04/14/2025

Join us in congratulating Teddy Akiki, MD on his promotion to Assistant Professor! 🎉

As a physician-scientist, Dr. Akiki’s groundbreaking work in neurocomputational psychiatry integrates AI, multimodal neuroimaging, and translational therapeutics to revolutionize psychiatric care. His research aims to enhance precision diagnosis and treatment for mood, anxiety, and trauma-related disorders—driving precision psychiatry forward!

We’re thrilled to celebrate this well-deserved achievement! 👏

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401 Quarry Road
Palo Alto, CA
94304

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