Journal of Pediatric Gastroenterology and Nutrition

07/23/2025

Can early nutrition improve long-term neurodevelopment in moderate and late preterm infants?

This prospective cohort study of 100 MLPT infants found:
🧠 Cognitive, language, and motor scores at age 2 were within normal limits
🔍 No association between first-week protein/energy intake and neurodevelopmental outcomes
👦 Boys scored significantly lower than girls on cognitive and language scales

These results suggest other factors may play a larger role in outcomes for this preterm group.

Read more: https://doi.org/10.1002/jpn3.70056?utm_source=fb_page&utm_medium=Journal+of+Pediatric+Gastroenterology+and+Nutrition&utm_campaign=publer

Objectives Long-term neurodevelopment of moderate and late preterm infants (MLPTI; gestational age [GA] 32 0/7 weeks to 36 6/7 weeks) is at a lower level than that of those at term age. Increased pr...

07/22/2025

New data from the Military Health System shows a steady decline in pediatric hospitalizations for acute pancreatitis (AP) from 2018 to 2023—including during the COVID-19 pandemic.

📉 No significant pandemic-related shifts were seen
👧🏽 Female s*x and older age were associated with higher hospitalization rates
🦠 The drop may reflect fewer viral infections or trauma cases, or more standardized care

Read the full study, which raises important questions about evolving trends in pediatric AP:

🔗 https://doi.org/10.1002/jpn3.70086?utm_source=fb_page&utm_medium=Journal+of+Pediatric+Gastroenterology+and+Nutrition&utm_campaign=publer

07/21/2025

🚨 Pediatric liver transplants (pLT) in Europe are decreasing, according to the 2022 ELITA-ESPGHAN report.

📊 Key findings:
– 585 pLTs in 2022, third straight year of decline
– Living donation stable (34%), suggesting other factors beyond organ shortage
– Most graft failures and deaths occurred in the first 6 months
– Older donor age linked with worse graft survival

Improved perioperative care and innovation like machine perfusion may help address risks.

🔗 https://doi.org/10.1002/jpn3.70065?utm_source=fb_page&utm_medium=Journal+of+Pediatric+Gastroenterology+and+Nutrition&utm_campaign=publer

07/18/2025

🫁 Children with cystic fibrosis (CF) often face liver complications, including CF hepato-biliary involvement (CFHBI).

New findings from Sweden show that:
✅ Liver stiffness significantly decreased after starting elexacaftor–tezacaftor–ivacaftor (ETI)
✅ Improvements were seen even in those with CFHBI
✅ Lung function also improved post-ETI

These early data suggest ETI may positively impact liver health—not just lungs—in pediatric CF.

🔗 https://doi.org/10.1002/jpn3.70050?utm_source=fb_page&utm_medium=Journal+of+Pediatric+Gastroenterology+and+Nutrition&utm_campaign=publer

07/17/2025

🚨 In pediatric Crohn’s disease, perianal lesions (like skin tags or fissures) are common and increase the risk of fistula.

But can symptoms like pain or discharge help us detect them?

🧪 This new study found:
🔹 No correlation between symptoms and presence of perianal lesions
🔹 15% of asymptomatic patients still had inflamed skin tags

👩‍⚕️ Bottom line: Routine perianal exams are essential—regardless of symptoms.

🔗 https://doi.org/10.1002/jpn3.70071?utm_source=fb_page&utm_medium=Journal+of+Pediatric+Gastroenterology+and+Nutrition&utm_campaign=publer

07/16/2025

😴 Children and teens with inflammatory bowel disease (IBD) often deal with poor sleep and fatigue.

This new randomized controlled trial shows that:
📈 Sleep tracking improved fatigue scores
🛌 In-person sleep hygiene counseling further improved bedtime habits (like putting screens away!)

💡 Simple, inexpensive strategies like these can make a big difference in the daily lives of children with IBD.

🔗 Read the full article here: https://doi.org/10.1002/jpn3.70066?utm_source=fb_page&utm_medium=Journal+of+Pediatric+Gastroenterology+and+Nutrition&utm_campaign=publer

07/15/2025

🧠 Inflammatory bowel disease in children is increasingly monitored using intestinal ultrasound (IUS)—but what’s “normal” bowel wall thickness (BWT) in remission?

📊 This multicenter study from the Pediatric Committee of IBUS evaluated 98 children in deep remission and found:
✔️ Median BWT = 1.4 mm
✔️ All BWT

07/14/2025

💡 Children with IBD often face more than just physical symptoms—many report anxiety, depression, and fatigue.

This new open access study tested routine mental and physical health screening in clinic using patient-reported outcome measures (PROMs):

🧾 2910 PROMs sent
📈 45% adherence
😷 82% reported fatigue or pain
🧠 20% reported anxiety or depression

📊 Patients found it helpful—though some noted length/frequency of the PROMs was a barrier. Still, the takeaway is clear: routine mental & medical health screening is feasible in pediatric IBD care.

🔗 Read more: https://doi.org/10.1002/jpn3.70039?utm_source=fb_page&utm_medium=Journal+of+Pediatric+Gastroenterology+and+Nutrition&utm_campaign=publer

07/14/2025

Do synbiotic-supplemented formulas make a difference?
The ESPGHAN Special Interest Group on Gut Microbiota have released their technical review on the use of synbiotic-supplemented formulas in healthy full-term infants, laying the groundwork for ESPGHAN’s upcoming position paper.
Based on 16 clinical trials published before 2024, the results suggest synbiotic formulas are safe and well-tolerated, with no significant differences in growth, stool patterns, gastrointestinal symptoms, or infection rates compared to standard formulas.
📖 Dive in to the full review here: https://ow.ly/8c7x50WfrVc?utm_source=fb_page&utm_medium=Journal+of+Pediatric+Gastroenterology+and+Nutrition&utm_campaign=publer.

This technical review, one of five developed by the European Society for Pediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) special interest group (SIG) on gut microbiota and modifications...

07/13/2025

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07/12/2025

Did you know that JPGN has an entire collection of articles that are eligible for , with more being added each month?

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07/11/2025

🧒🦴 Low bone mineral density (BMD) is a concern in children with IBD—but who’s at highest risk?

This large cohort study (n=600) found:
🔹 Only 7% had low spine BMAD (adjusts for growth delay)
🔹 Lower BMI & height strongly predicted low BMD
🔹 Steroid use was associated with poorer bone outcomes
🔹 Polygenic risk scores may flag vulnerable patients earlier

📍 Key takeaway: Growth parameters and genetic risk may help guide DXA screening in pediatric IBD.

🔗 Full article: https://doi.org/10.1002/jpn3.70047?utm_source=fb_page&utm_medium=Journal+of+Pediatric+Gastroenterology+and+Nutrition&utm_campaign=publer