Congenital Hyperinsulinism Center at CHOP

Congenital Hyperinsulinism Center at CHOP Congenital hyperinsulinism (HI) is a disorder that causes low blood sugar in infants and children.

Since October 1998, the HI Center at CHOP has evaluated and treated more than 1200 patients — making it the largest program of its kind in the world. Since October 1998, the HI Center at CHOP has evaluated and treated more than 800 patients — making it the largest program of its kind in the world.

Calling all providers. Please consider joining us for our upcoming HI Symposium.
04/22/2026

Calling all providers. Please consider joining us for our upcoming HI Symposium.

02/18/2026

Our team at the Congenital Hyperinsulinism Center at CHOP has a study to understand how cognitive function changes over time in children with HI. You will be asked to come to CHOP for 3 study visits (one each year) that will each last about 2 hours. At the visit. you will be asked to complete neurocognitive tasks (like computer games) and surveys. Travel support and compensation for your time are provided.
You may be eligible for this study if you are 7 to 15 years old and you have a diagnosis of either congenital hyperinsulinism (CHI) or are a healthy volunteer. If you’re interested in learning more, please contact us at HIresearch@chop.edu!

01/23/2026

Our team has a new clinical trial for individuals 2 years and older to look at the safety, tolerability, and effectiveness of a new investigational drug called HM15136 which is not yet FDA-approved. HM15136 is a long-acting glucagon analogue given weekly by injection. It is designed to act like glucagon, a hormone produced by the pancreas that helps the body maintain normal blood sugar levels. Total participation time is up to 22 weeks which includes up to 13 study visits and 8 weekly injections of HM15136. Travel and compensation are provided. For more information, please contact us at HIResearch@chop.edu or visit https://www.research.chop.edu/hm15136-for-the-treatment....

10/31/2025

Happy Halloween!🎃👻Please share pictures of your families Halloween costumes!

We're thrilled to once again be ranked among the very best in the nation for Endocrinology by U.S. News and World Report...
10/07/2025

We're thrilled to once again be ranked among the very best in the nation for Endocrinology by U.S. News and World Report!

Children’s Hospital of Philadelphia was again named one of the nation’s best pediatric hospitals by U.S. News & World Report.

It is National Advanced Practice Providers Week. We want to take this time to recognize and thank our wonderful APP's fo...
09/25/2025

It is National Advanced Practice Providers Week. We want to take this time to recognize and thank our wonderful APP's for their APPceptional work they do for our patients! We are so happy to have Heather, Emily and Molly on our team!!!🌺🌸

09/24/2025

Calling all siblings, friends, and family of the hyperinsulinism community!
We are looking for healthy volunteer participants for a study to understand how cognitive function changes over time in children with hyperinsulinism.
You will be asked to come to CHOP for 3 study visits (one each year) that will each last about 2 hours. At the visit, you will be asked to complete neurocognitive tasks (like computer games) and surveys. Travel support and compensation for your time are provided.
You may be eligible for this study if you are 7 to 15 years old and you have a diagnosis of either congenital hyperinsulinism or are a healthy volunteer. If you’re interested in learning more, please contact us at HIresearch@chop.edu!

07/23/2025

Our team has a new clinical trial for individuals 2 years and older to look at the safety, tolerability, and effectiveness of a new investigational drug called HM15136 which is not yet FDA-approved. HM15136 is a long-acting glucagon analogue given weekly by injection. It is designed to act like glucagon, a hormone produced by the pancreas that helps the body maintain normal blood sugar levels. Total participation time is up to 22 weeks which includes up to 13 study visits and 8 weekly injections of HM15136. Travel and compensation are provided. For more information, please contact us at HIResearch@chop.edu or visit https://www.research.chop.edu/hm15136-for-the-treatment-of-congenital-hyperinsulinism-research-study.

06/07/2025

Save the date!
05/14/2025

Save the date!

Happy Nurses Week!!
05/09/2025

Happy Nurses Week!!

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Philadelphia, PA
19104

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