Donna M. Galarza, CN

07/27/2025

Many children on the spectrum that I have tested all have very low cholesterol!

07/25/2025

Been following DR Mellilo for years! He's great

07/06/2025

Rand Paul MD speaking truth!

06/26/2025

Love Dr Peter McCullough!Research at its best!

05/23/2025

So convenient and effective!

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04/04/2025

Love Dr Amen!! Speaking truth and facts

03/31/2025

A very misunderstood malady

New research: EDS and 4 x more anxiety but no mention of GABA, serotonin or zinc or vitamin B6

From -Danlos Support UK ... "A groundbreaking study led by Dr. Jessica Eccles and published in The British Journal of Psychiatry has uncovered key brain mechanisms behind the strong connection between joint hypermobility and anxiety.

Key Findings:
- People with hypermobility show heightened activity in the amygdala (threat processing) and insular cortex (internal body signals), increasing anxiety sensitivity.
- Hypermobile individuals are 4x more likely to experience anxiety than the general population.
- Stronger brain connectivity between the amygdala and precuneus (self-awareness), possibly explaining increased anxiety levels.

This research does not suggest that EDS or HSD are "all in your head." These are real, physical conditions with complex causes. Instead, the study highlights how mental health challenges can accompany the physical symptoms, offering a more complete understanding of the brain-body connection and potential treatments for anxiety in hypermobile individuals.

Dr Eccles explained, “This research could lead to personalised treatments that help regulate brain activity and reduce anxiety symptoms for those with hypermobility.”

Hypermobility's impact on mental health is often overlooked. This study brings hope for better understanding and specialised therapies. Read the full study below"

My insights - I appreciate the fact that the connection between anxiety and EDS is being recognized (4x higher incidence of anxiety is high!) and that personalized approaches are mentioned. Biofeedback and neurofeedback are both mentioned which is great.

Unfortunately, there is no mention of nutritional support like GABA ("dysregulated GABAergic inhibition in the amygdala has long been implicated in stress-related neuropsychiatric disorders") or tryptophan ("The amygdala is a key player in the processing of fear. This brain area is prominently modulated by the neurotransmitter serotonin").

Also there is role for zinc and vitamin B6 in the amygdala and there does seem to be a pyroluria/social anxiety connection to EDS. And these co-factors are needed to make GABA and serotonin.

If you have EDS and anxiety, has GABA or tryptophan/-5HTP or zinc or vitamin B6 helped - mentally and/or physically?

03/28/2025

We need more info on women!!
Many studies are done on men

03/15/2025

Too scarey!!

03/12/2025

Interesting scientific facts!