10/21/2025
Whether it’s you or someone you love who is living with bipolar disorder with depression (BD-D), you know how overwhelming the lows can be. Managing episodes of depression can at times feel more challenging or longer lasting than the manic episodes, and can cause sufferers to feel alone — despite the fact that BD-D affects around 1% of the adult population in any given year1. For nearly half of people diagnosed with bipolar depression, taking treatments that are currently available will not help them reach full remission. But researchers are working to develop new care options — and volunteers are helping advance scientific research by participating in clinical trials every day.