01/27/2026
Cannabis Compounds Kill Deadly Fungal Infections Better Than Current Drugs—Scientists Are Shocked. Scientists say it may be the key to beating deadly fungal infections.
“Two compounds found in cannabis—cannabidiol (CBD) and cannabidivarin (CBDV)—have demonstrated potent antifungal properties in a breakthrough study from Macquarie University.
Researchers discovered that these non-psychoactive and mildly psychoactive compounds effectively killed Cryptococcus neoformans, a lethal fungus responsible for life-threatening meningitis. In lab tests, CBD and CBDV acted even faster than standard antifungal medications, disrupting fungal membranes and metabolic pathways.
The compounds also eliminated common skin fungi, such as those that cause athlete's foot and jock itch.
To explore real-world potential, scientists used moth larvae with immune systems similar to mammals. When infected larvae were treated topically with CBD, their survival rate nearly matched that of uninfected controls—outperforming current gold-standard antifungal treatments.
While more research is needed before human use, especially for internal infections, the study paves the way for CBD-based topicals to combat skin fungal infections.
With drug resistance on the rise and fungal infections becoming increasingly difficult to treat, cannabis compounds could offer a timely and natural new defense. Current antifungal drugs are losing effectiveness as fungi evolve resistance, making the search for alternative treatments urgent.
This discovery reveals yet another medical application hidden inside the cannabis plant—one that could save lives as drug-resistant infections spread globally.
Reference: Macquarie University study on cannabis compounds and antifungal properties - "CBD and CBDV antifungal efficacy"
Article written by Jamie Novotny