Dr. Brittany Krake

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United States
Portland, OR
Dr. Brittany Krake

Regenerative and Functional Medicine for Pain, Performance & Hormones.

03/16/2026

No Sunday Scaries when your Monday looks like this.

02/19/2026

I woke up this morning and my heart is happy.

Clinicians across the country are posting about the framework I presented on last night, hosted by Clinicians are asking about “terrain” when it comes to PRP injections. They’re talking about hormone receptors in MSK tissue.

THIS IS SUCH AN IMPORTANT CONVERSATION IN PAIN AND MSK INTERVENTIONS.

We don’t have all the answers yet. But here’s what we DO know:
1) Estrogen, progesterone and testosterone receptors exist in bones, tendons, ligaments, cartilage
2) Growth factor signaling (TGF-beta, IGF-1) is hormone-dependent
3) 70% of menopausal women report joint pain and 40% have NO structural findings on imaging
4) 99% of preclinical aging studies ignore menopause (Nature Aging, 2024), including those looking at PRP

So why WOULDN’T we question or consider hormonal terrain before—or alongside—PRP?

The terrain model isn’t just a metaphor. It’s a call to revolutionize how we approach regenerative medicine for women (and men with changing hormones, too).

To every clinician interested in these questions: THANK YOU. Keep going. Our patients need us to think differently. I am so excited to see where this conversation takes us.

What questions do you have about hormonal terrain and regenerative medicine? Drop them below. 👇

02/05/2026

One of the most frustrating parts of treating frozen shoulder is how many women tell me:

“I didn’t know…

… this was a thing.”
… I was at higher risk.”
… who I should go see first.”
… that early treatment was important.”
… there were other options.”

Frozen shoulder is more common in women, particularly during perimenopause and menopause. Yet musculoskeletal symptoms are rarely discussed as a major player in this hormonal transition. So women often navigate stiffness, pain, and loss of function without a framework, bouncing between providers or being told to “wait it out.”

When appropriate, comprehensive care can include physical therapy AND hormone support, AND regenerative, volume-based injections — earlier, not as a last resort.

I love treating shoulders. Truly.
And little is as satisfying as knowing that early, effective intervention may have saved someone months to years of pain, prolonged PT, and loss of function.

This is about reducing suffering and expanding what good care looks like for women.

If this resonates, share it with a woman who’s been told to “just stretch it out.”

01/27/2026

This week my heart is heavy. Like so many, I’ve been following the news of those killed during encounters with federal immigration enforcement — people who posed no imminent threat, whose deaths have shaken communities and raised urgent questions about accountability.

As a physician, my first commitment is to do no harm. In the Naturopathic Physician’s Oath, we pledge to care for individuals without discrimination, to protect human dignity, and to serve not only our patients, but the health of our communities. That responsibility does not end in the exam room…

We are trained and called to be helpers. To run toward suffering. To protect life.

What has stayed with me most in the public accounts of Alex Pretti is this: even in his final moments, we watched him help. Care was present. Humanity was present. And it was met with violence.

What is happening in the world affects me deeply, too. Fear and injustice live in bodies, nervous systems, and families. Medicine is inseparable from humanity. Public health is inseparable from safety, trust, and justice.

Silence is not neutrality. And care demands courage.

I will continue showing up for you, as a physician, as a helper, and as a human, committed to compassion, advocacy, and doing no harm regardless of race, ethnicity, immigration status, s*x, gender, age, abilities, religion, political beliefs, and so on. You get to be human and I will see you as such.

The only way out of this mess is through shared humanity.

01/23/2026

I hear it from so many of my patients, and -absolutely, yes- i’m deep in it too. If it feels harder to regulate your nervous system right now… it makes sense.

We’re living in a moment where distressing news is always available, stress is constant, and your body is actually just trying to keep you safe with the input.

And during perimenopause + menopause, nervous system regulation really matters. Stress physiology amplifies:
• inflammation + pain
• sleep disruption
• cravings + blood sugar swings
• fatigue + slower recovery
Symptoms that already show up with a changing hormonal landscape.

So let me give you a little peace of mind… you don’t need perfect calm at every moment.

But you do need moments of safety—small, repeatable practices that help your body come back online… so you can keep showing up for yourself, your health, and the social endurance this season demands.

Save this + try one tool today:
humming or singing
tapping (EFT)
dancing for 60 seconds
feet on the ground outside
hand on heart + long exhale

Let’s do each other a favor… can you share just one regulation practice that you find most helpful right now?

01/22/2026

Perimenopause doesn’t just change your cycle.
It changes how you recover.
How you build muscle.
How your joints handle load.
How inflammation shows up.

You’re not weak and you’re definitely not broken.
You’re in a new physiology — and you deserve care that understands that.

Strength isn’t punishment. It’s protection.

Follow for hormone-informed strength + joint support.
📍Local? Book through my Linktree.

01/19/2026

Perimenopause doesn’t just change your cycle.
It can change your joints. Your recovery. Your strength. Your responsiveness.

It’s not usually what brings perimenopausal patients in (thanks irritability, insomnia, heavy periods), but is often mentioned as a side note:
“I’ve never had knee pain before.”
“Why do my shoulders feel stiff?”
“Why am I suddenly getting pain in the bottom of my feet?”
“Why does exercise feel harder than it used to?”

You’re not imagining it. This is one of the most overlooked parts of perimenopause:
muscle + connective tissue + inflammation + recovery shift. And there are evidence-based ways to support this!

01/14/2026

One of the most overlooked aspects of perimenopause and menopause is how profoundly hormonal shifts affect joints, muscle, and recovery.

For many women, musculoskeletal symptoms are the first signal — long before labs change.

This isn’t something to push through.
It’s something to understand so that we can treat and train in the ways that will help women longterm.

01/12/2026

Things I’m reclaiming — not just for myself, but for the women I serve.

So many women feel the shift of perimenopause and menopause in their bodies long before labs change — through joint pain, fatigue, mood changes, slower recovery, or a sense that something is “off.”

None of that is random.
And none of it means you’re failing.

The menopausal transition isn’t something to push through. It’s a transition that deserves precision, respect, and early care that actually reflects women’s physiology.

12/31/2025

Sunrise over Mt. Hood. Ultrasound on the screen.

Looking back on a few of my favorite and most fulfilling regenerative injection cases of 2025 — restoring movement in perimenopausal and andropause-induced frozen shoulders, working through complex post-surgical nerve entrapment, and - as always - helping athletes continue doing what they love for as long as possible (so many knees).

Grateful for the trust, the work, and the cases that have deepened my practice these past 7 years, and excited for the conversations these cases are shaping for 2026.

07/30/2025

What happens in Vegas... gets pipetted into tubes for and protein concentrate research!

Thanks for hosting an inspiring meeting to design new research for better understanding patient outcomes and the longevity of these therapies we love.

Sunday provided invaluable insight and training on injection preparation. As always, looking forward to bringing fresh new ideas and approaches back to my patients!

Swipe to see my favorite new PRP “toy”… I’ve been loving the customizable nature of this platelet rich and platelet poor plasma prep.

11/10/2022

And the a holistic approach to interpretation that makes EVERYTHING make sense.

Just this week, 3 patients have told me that they are tired of being a “ping pong ball” between specialists who point their fingers and say that their problem is best served by someone else. For each patient, I agreed with every single lab interpretation made… no one was wrong! But each practitioner had neglected to make the connection BETWEEN organ systems to determine the root cause, and each patient has been suffering for years 😢

New hope for chronic pain, for functional hormone imbalances, and for autoimmunity. This is why I love what I do with every fiber of my being.

Address

Portland, OR
97086-97299

Website

http://www.drbrittanykrake.com/

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