
09/21/2025
Choroidal neovascularization is the growth of abnormal blood vessels from the choroid that pe*****te Bruch's membrane into the sub-RPE and/or subretinal space. These vessels are fragile and prone to leakage and tearing, leading to subretinal fluid, hemorrhage, and scarring — all of which can cause severe, permanent central vision loss if untreated. Hemorrhaging from a choroidal neovascularization classically enters the subretinal space. In this image, in addition to the subretinal hemorrhage, an intraretinal hemorrhage, specifically a hemorrhage within Henle's layer is present, identifiable by the petalloid appearance of the inferior, nasaly and superior margins of the hemorrhage.
CNV is most commonly associated with wet age-related macular degeneration (AMD), but it can also occur in conditions like pathologic myopia, punctate inner choroidopathy, ocular histoplasmosis, or angioid streaks.
Prompt diagnosis and treatment with intravitreal anti-VEGF therapy can stabilize or even improve vision. Swipe to see how CNV presents on fundus imaging — and why timely referral is key.