Sheridan Lane Assisted Living

09/29/2025

The Gender Gap in Alzheimer's

Recent research published in JAMA reveals that approximately two-thirds of Alzheimer's patients are women, who not only develop the disease more frequently but experience it differently—with faster tau accumulation and more rapid cognitive decline despite similar amyloid β levels. https://tinyurl.com/383m94pz

Harvard neuropsychologist Rachel Buckley, PhD, noted. “Women actually tend to live with dementia for much longer than men.”
Perhaps most concerning for treatment equity: clinical trials show women may benefit 31% less from breakthrough antiamyloid therapies than men. Meanwhile, the APOE4 genetic variant increases Alzheimer's risk more substantially in women, and even common risk factors like diabetes and poor sleep appear to impact women's cognition disproportionately.

The challenge for medicine will be less about applying universal approaches and more about recognizing these fundamental s*x differences in research, prevention, and treatment.

Starting next spring, we will feature a series on memory care, highlighting the latest research, innovative therapies, and expert discussions on the multifactorial causes of dementia.

More research can be accessed here https://tinyurl.com/bdcbmz3p


https://tinyurl.com/bdcbmz3p

09/27/2025

The Gender Gap in Alzheimer's

Recent research published in JAMA reveals that approximately two-thirds of Alzheimer's patients are women, who not only develop the disease more frequently but experience it differently—with faster tau accumulation and more rapid cognitive decline despite similar amyloid β levels. https://tinyurl.com/383m94pz

Harvard neuropsychologist Rachel Buckley, PhD, noted. “Women actually tend to live with dementia for much longer than men.”

Perhaps most concerning for treatment equity: clinical trials show women may benefit 31% less from breakthrough antiamyloid therapies than men. Meanwhile, the APOE4 genetic variant increases Alzheimer's risk more substantially in women, and even common risk factors like diabetes and poor sleep appear to impact women's cognition disproportionately.

The challenge for medicine will be less about applying universal approaches and more about recognizing these fundamental s*x differences in research, prevention, and treatment.

Starting next spring, we will feature a series on memory care, highlighting the latest research, innovative therapies, and expert discussions on the multifactorial causes of dementia.

To learn more about our memory care program, services, or to schedule a tour, feel free to contact us at (602) 670-9326 or email us at info@deserthavenaz.com

More research can be accessed here https://tinyurl.com/bdcbmz3p


https://tinyurl.com/bdcbmz3p

09/27/2025

New findings from Alzheimer’s Disease International and The Lancet reveal a powerful truth: nearly half of dementia cases worldwide could be prevented or delayed through proactive measures.

Fourteen risk factors now stand out, from less education in youth to social isolation, poor vision, and high LDL cholesterol in later years. The evidence is clear—prevention across the life course matters. Mid-life (18–65) is especially critical, with interventions showing the biggest impact.

Importantly, the research underscores that people in low- and middle-income countries, and those from disadvantaged backgrounds, are most at risk—but also stand to benefit the most from prevention. A healthier future requires investing in education, healthcare access, and community support at every stage of life.

For further insights on healthcare reform in Arizona and the United States, explore additional analyses by Promised Land Healthcare Group and The Zambakari Advisory:

Healthcare Blogs: https://tinyurl.com/bdcbmz3p

Our Special Issue on Healthcare: https://tinyurl.com/skheyudj

Social Sciences Research Network https://tinyurl.com/5f5zmxc5


https://tinyurl.com/yz8837pa

The research, commissioned by The Lancet revised their 2020 findings to include failing eyesight and high LDL cholesterol as risk factors for dementia.

09/26/2025

Balancing Nutrition and Enjoyment in Later Life

Nutrition plays a vital role in healthy aging, but it’s not just about restriction. Tara Schmidt, Mayo Clinic dietitian, reminds us that eating should also bring joy and social connection. Many older adults face challenges like decreased appetite, altered taste, or complex health conditions, but small, sustainable adjustments can make a big difference.

Protein remains a cornerstone for maintaining muscle mass, especially when paired with regular strength activity. Fiber-rich foods like beans, vegetables, and whole grains support digestion, while calcium and vitamin D help protect bones after menopause and into later years. Hydration is equally critical — and it doesn’t have to be plain water. Milk, tea, smoothies, and even hydrating foods like fruit or soup can help.

Importantly, Schmidt stresses balance over perfection: a B+ diet is far better than none. Sharing a favorite treat with family or friends is part of well-being too. By focusing on nutrient-dense foods most of the time — while still enjoying life’s pleasures — older adults can age with strength, stability, and joy.

For further insights on healthcare reform in Arizona and the United States, explore additional analyses by Promised Land Healthcare Group and The Zambakari Advisory:

Healthcare Blogs: https://tinyurl.com/bdcbmz3p

Our Special Issue on Healthcare: https://tinyurl.com/skheyudj

Social Sciences Research Network https://tinyurl.com/5f5zmxc5


http://bit.ly/4pezz9N

Desert Haven AZ offer excellent assisted living care in a family environment, including Supervisory, Assisted, and Directed Care, Short-term respite stays, Memory support e.g. Alzheimer’s disease, dementia. We also have 24/7 on-duty, awake staff and an On-Call Nurse Practitioner (NP).

09/26/2025

The Surprising Role of Tau in Infants

When we talk about Alzheimer’s disease (AD), one of the most recognizable biomarkers is phosphorylated tau (p-tau), a protein linked to neurodegeneration when it misfolds and aggregates. But groundbreaking research has revealed something surprising—healthy newborns have higher p-tau217 levels than people with AD.

A new study, using umbilical cord blood samples, found levels nearly three times greater in newborns than in Alzheimer’s patients. Unlike in adults, however, infants’ brains seem to manage these elevated levels without harmful aggregation. This raises profound questions: What protective mechanisms do infants have that adults lack? Could unlocking these processes help prevent tau-related neurodegeneration later in life?

Researchers suspect unique clearance mechanisms or structural differences in “fetal tau” proteins may play a role. Understanding this could lead to innovative therapies that combine amyloid-targeting drugs with strategies to prevent tau aggregation—potentially transforming Alzheimer’s treatment.

The implications go far beyond one disease, offering new insight into brain development, resilience, and repair.

🔗 Read the full article here https://tinyurl.com/46jp3pau

For further insights on healthcare reform in Arizona and the United States, explore additional analyses by Promised Land Healthcare Group and The Zambakari Advisory:

Healthcare Blogs: https://tinyurl.com/bdcbmz3p

Our Special Issue on Healthcare: https://tinyurl.com/skheyudj

Social Sciences Research Network https://tinyurl.com/5f5zmxc5

09/19/2025

The End of Democratic Capitalism? How Inequality and Insecurity Fueled a Crisis in the West
By Daron Acemoglu, Foreign Affairs, July/August 2023

Is democratic capitalism unraveling? Daron Acemoglu, MIT economist, believes so. In his July/August 2023 Foreign Affairs essay, he reviews two timely works—Martin Wolf’s The Crisis of Democratic Capitalism and Pranab Bardhan’s A World of Insecurity. Both authors dissect the erosion of trust in democracy across the West, where rising inequality and growing insecurity have left many citizens alienated from political and economic institutions.

Wolf traces the malaise to a breakdown between capitalism and democracy, fueled by decades of globalization and deregulation that prioritized capital over labor. Bardhan argues insecurity—fear of job loss, declining incomes, and rapid cultural change—better explains the democratic crisis. Both agree that institutional failure, not “incompetent citizens,” is at the core of today’s discontent.

Acemoglu stresses that solutions lie in rethinking growth itself. Governments must regulate technology to empower workers, not replace them, and reinvest in jobs that restore dignity and purpose. Without rebuilding trust and a shared sense of prosperity, democratic capitalism risks giving way to authoritarian alternatives.

Explore additional analyses by The Zambakari Advisory:

Georgetown Public Policy Review https://tinyurl.com/2ht45bku

Fletcher School of Law and Diplomacy https://tinyurl.com/8zpmesre

Social Sciences Research Network https://tinyurl.com/5f5zmxc5

Zambakari Advisory https://tinyurl.com/52n9avf6
https://tinyurl.com/4zbybdds

How inequality and insecurity fueled a crisis in the West.

09/18/2025

Balancing Nutrition and Enjoyment in Later Life

Nutrition plays a vital role in healthy aging, but it’s not just about restriction. Tara Schmidt, Mayo Clinic dietitian, reminds us that eating should also bring joy and social connection. Many older adults face challenges like decreased appetite, altered taste, or complex health conditions, but small, sustainable adjustments can make a big difference.

Protein remains a cornerstone for maintaining muscle mass, especially when paired with regular strength activity. Fiber-rich foods like beans, vegetables, and whole grains support digestion, while calcium and vitamin D help protect bones after menopause and into later years. Hydration is equally critical — and it doesn’t have to be plain water. Milk, tea, smoothies, and even hydrating foods like fruit or soup can help.

Importantly, Schmidt stresses balance over perfection: a B+ diet is far better than none. Sharing a favorite treat with family or friends is part of well-being too. By focusing on nutrient-dense foods most of the time — while still enjoying life’s pleasures — older adults can age with strength, stability, and joy.

For further insights on healthcare reform in Arizona and the United States, explore additional analyses by Promised Land Healthcare Group and The Zambakari Advisory:

Healthcare Blogs: https://tinyurl.com/bdcbmz3p

Our Special Issue on Healthcare: https://tinyurl.com/skheyudj

Social Sciences Research Network https://tinyurl.com/5f5zmxc5


http://bit.ly/4pezz9N