12/22/2025
🧠 5 Hormones That Make Metabolism Harder After 40
(and it’s NOT willpower)
If fat loss suddenly feels harder after 40, let me be clear:
👉 It’s not because you “stopped trying.”
👉 It’s not because you’re undisciplined.
It’s because your body is under oxidative stress — the quiet disruptor that throws hormones off before you ever notice symptoms.
Here are the big 5 hormones that take the hit 👇
🔥 1. Thyroid (T4 → T3)
Your thyroid sets the pace for metabolism.
Oxidative stress:
• Blocks T4 → T3 conversion
• Interferes with thyroid signaling
• Slows calorie burn
➡️ You feel tired, cold, and stuck despite “doing everything right.”
💪 2. Testosterone (men AND women)
This hormone protects muscle, metabolism, and insulin sensitivity.
Oxidative stress:
• Lowers production
• Weakens receptor response
➡️ Less muscle + more fat = slower metabolism.
🍽️ 3. GLP-1 (your appetite hormone)
This controls hunger, cravings, and blood sugar.
Oxidative stress:
• Disrupts gut signaling
• Reduces GLP-1 release
➡️ Cravings, blood sugar swings, weight regain.
(Yes — this is why gut health matters FIRST.)
😴 4. Growth Hormone (HGH)
This is your repair-and-burn-fat hormone while you sleep.
Oxidative stress:
• Disrupts deep sleep
• Suppresses pituitary signaling
➡️ Poor recovery, stubborn belly fat, faster aging.
🌸 5. Estrogen (women)
Hormone imbalance isn’t always “low estrogen.”
Oxidative stress:
• Alters estrogen metabolism
• Pushes inflammatory pathways
➡️ Inflammation, fat storage, hormone chaos.
🚨 The real takeaway
Hormones don’t just “fail with age.”
They struggle in an oxidative environment.
You can’t diet your way out of this.
You can’t out-exercise mitochondrial damage.
Lower oxidative stress FIRST —
and the body remembers how to regulate itself again.
That’s when metabolism actually turns back on.
👉 DM me “METABOLIC RESET”
I’ll share the exact protocol we use to calm oxidative stress, support the gut, and help hormones work with you again.
