Gerti Tashko, M.D.

Gerti Tashko, M.D. • Endocrinology, Diabetes and Metabolism
• Obesity Medicine
• Hypertension
• Lipidology

Untreated obstructive sleep apnea places repeated stress on the heart each night. Oxygen drops, pressure changes, and ne...
12/22/2025

Untreated obstructive sleep apnea places repeated stress on the heart each night. Oxygen drops, pressure changes, and nervous system surges quietly remodel the atria over time. This process raises the risk of atrial fibrillation and makes rhythm control harder. Understanding this link helps patients address a major, often overlooked contributor to heart rhythm instability.

↘ What Happens During Obstructive Sleep Apnea
↘ 1. Intermittent Hypoxia and Oxidative Stress
↘ 2. Autonomic Nervous System Imbalance
↘ 3. Blood Pressure, Vascular Stress, and Atrial Remodeling
↘ 4. Intrathoracic Pressure and Atrial Stretch
↘ Summary Table: How OSA Promotes Atrial Fibrillation
↘ Why Treating OSA Changes A.fib Outcomes
↘ Patient Cases from Clinical Practice
↘ The Broader Metabolic and Cardiovascular Context
↘ Takeaway

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Dr. Tashko explains how untreated sleep apnea drives atrial fibrillation through hypoxia, inflammation, and atrial remodeling.

Nonalcoholic fatty liver disease reflects deeper metabolic imbalance rather than liver fat alone. This article explains ...
12/21/2025

Nonalcoholic fatty liver disease reflects deeper metabolic imbalance rather than liver fat alone. This article explains how visceral fat, insulin resistance, and inflammation drive progression, when reversal remains achievable, and how treatment differs between simple fatty liver and more advanced stages with inflammation and fibrosis.

↘ How Fat Accumulates in the Liver
↘ From Simple Steatosis to Inflammation
↘ Fibrosis and Long-Term Consequences
↘ Summary Table: MASLD Progression Pathway
↘ Reversal: What Actually Works
↘ Why Some Patients Progress Despite Effort
↘ Patient Cases From Clinical Practice
↘ A Broader Metabolic Perspective
↘ Takeaway

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Dr. Tashko explains how nonalcoholic fatty liver disease progresses, why it reverses in many patients, and how metabolic care changes outcomes.

Visceral fat plays a central role in metabolic disease, even when body weight appears stable. As subcutaneous fat reache...
12/20/2025

Visceral fat plays a central role in metabolic disease, even when body weight appears stable. As subcutaneous fat reaches its storage limit, excess calories shift toward visceral fat, driving inflammation and insulin resistance. This process explains why metabolic syndrome, diabetes, and cardiovascular risk often emerge together. Understanding fat distribution allows earlier and more effective metabolic intervention.

↘ Subcutaneous Fat as the Body’s Safe Storage
↘ When Subcutaneous Capacity Reaches Its Limit
↘ Visceral Fat as Metabolically Active and Harmful
↘ The Vicious Cycle of Visceral Fat and Insulin Resistance
↘ How Visceral Fat Connects Multiple Conditions
↘ Why Waist Size Matters More Than Weight
↘ Patient Scenarios From Clinical Practice
↘ Breaking the Cycle Requires a Broader Strategy
↘ Takeaway

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Dr. Tashko explains how visceral fat forms, why it drives insulin resistance and metabolic syndrome, and how early intervention improves long term metabolic health.

High-dose influenza vaccination may reduce hospitalizations in adults over 65. A large New England Journal of Medicine t...
12/19/2025

High-dose influenza vaccination may reduce hospitalizations in adults over 65. A large New England Journal of Medicine trial found fewer admissions for influenza and pneumonia compared with standard-dose vaccination. While absolute risks remain low, the relative reduction in severe outcomes carries meaningful implications for older adults with chronic conditions and winter vulnerability.

↘ Why vaccine dose matters after age 65
↘ How the GALFLU trial was designed
↘ Who participated in the study
↘ What the study found
↘ Key Outcomes From the GALFLU Trial
↘ How to interpret these numbers thoughtfully
↘ Understanding Relative and Absolute Risk Together
↘ Why hospitalization prevention matters beyond infection
↘ Patient cases from an integrated care perspective
↘ Practical takeaway

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Dr. Tashko reviews new evidence showing high-dose influenza vaccination may reduce hospitalizations in adults over 65 without added safety risk.

Insulin resistance changes how the body stores calories and shapes fat distribution patterns. The liver handles more glu...
12/17/2025

Insulin resistance changes how the body stores calories and shapes fat distribution patterns. The liver handles more glucose and fatty acids, which increases triglycerides and raises ApoB. Visceral fat grows faster, the waistline expands earlier, and the weight to waistline ratio worsens. These shifts influence cholesterol balance, blood pressure, and diabetes risk. Understanding these pathways helps patients identify early metabolic changes and prevent long term complications.

↘ 1. How Triglycerides Form Under Normal Insulin Function
↘ 2. How Insulin Resistance Alters Triglyceride Synthesis
↘ 3. How Caloric Surplus Intensifies Triglyceride Formation
↘ 4. The Waist-to-Height Ratio as a Metabolic Signal
↘ Patient Cases
↘ Summary Table
↘ Closing Thoughts

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Dr. Tashko explains how insulin resistance alters fat storage, raises triglycerides, and increases metabolic risk through clear, patient friendly guidance.

Heart rate variability, measured in milliseconds, tracks how the body adapts to stress and recovery. When HRV falls belo...
12/13/2025

Heart rate variability, measured in milliseconds, tracks how the body adapts to stress and recovery. When HRV falls below 40 ms, the nervous system may be strained. With modern wearables, anyone can measure HRV each morning to monitor recovery trends. Balanced sleep, hydration, and stress control help restore higher HRV and hormonal rhythm.

↘ The Science Behind HRV
↘ How HRV is Measured
↘ Why HRV Matters
↘ Common influences on HRV
↘ HRV as a Reflection of Recovery
↘ Summary Table
↘ How HRV Connects to Hormones and Metabolism
↘ Patient Case Examples
↘ Practical Tips to Support HRV
↘ The Broader Context of Care

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Dr. Tashko explains how heart rate variability values reflect stress, recovery, and resilience through personalized, holistic care.

Semaglutide 7.2 mg shows stronger weight reduction and deeper metabolic gains than the current 2.4 mg dose. New phase 3b...
12/12/2025

Semaglutide 7.2 mg shows stronger weight reduction and deeper metabolic gains than the current 2.4 mg dose. New phase 3b trials reveal major benefits for adults with obesity, with and without type 2 diabetes. Participants reached higher weight loss milestones and saw better waist and metabolic changes. These results highlight a meaningful new option for patients who need increased support.

↘ Why Researchers Studied a Higher Dose
↘ 1. Key Findings in Adults With Type 2 Diabetes (STEP UP T2D)
↘ 2. Key Findings in Adults Without Diabetes (STEP UP)
↘ Comparison of Both Trials
↘ Combined Outcomes for Semaglutide 7.2 mg
↘ Patient Scenarios
↘ How This Fits Into a Holistic Strategy
↘ Takeaway

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Dr. Tashko reviews new trials showing semaglutide 7.2 mg delivers stronger weight loss and HbA1c drop than 2.4 mg in adults with obesity

SGLT2 inhibitors deliver major advances in diabetes, heart, and kidney care. These medications lower glucose through kid...
12/08/2025

SGLT2 inhibitors deliver major advances in diabetes, heart, and kidney care. These medications lower glucose through kidney excretion and ease metabolic strain. They cut heart failure hospitalization by about thirty percent and slow kidney decline by thirty-five percent. They also support modest weight loss. Their insulin-independent action helps patients with complex metabolic profiles gain steady, durable improvement.

↘ How SGLT2 Inhibitors Work
↘ FDA-Approved SGLT2 Inhibitors
↘ Table 1: At-a-Glance: FDA-Approved SGLT2 Inhibitors
↘ Benefits for Blood Sugar Control and Weight Management
↘ Cardiovascular Protection
↘ Kidney Protection
↘ Additional Health Benefits
↘ Table 2: Clinical Benefits by the Numbers
↘ Common Side Effects and Safety Considerations
↘ Clinical Case Examples
↘ Who Should Consider SGLT2 Inhibitors
↘ Combining SGLT2 Inhibitors with Other Therapies
↘ Monitoring and Follow-Up

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Dr. Tashko reviews SGLT2 inhibitors for diabetes, heart, and kidney health. Discover if this breakthrough therapy fits your needs.

Strength and volume training influence the body and brain in unique ways. Strength training boosts focus, neural drive, ...
11/29/2025

Strength and volume training influence the body and brain in unique ways. Strength training boosts focus, neural drive, and insulin sensitivity, while volume training enhances endurance, mood, and fat metabolism. This article explains how combining both methods creates balanced exercise for metabolic and cognitive health, supporting patients across Maryland and through virtual care nationwide.

↘ Defining the Two Styles
↘ Cognitive Benefits: Power Versus Flow
↘ Metabolic Effects: Different Roads to the Same Goal
↘ Hormonal and Cellular Differences
↘ Case Variations
↘ Summary Table
↘ Integration: The Smart Strategy
↘ Why It Matters

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Dr. Tashko explains how strength and volume training shape differently cognition, hormones, and metabolism for balanced health.

Endocrine disruptors are chemicals that interfere with hormones and metabolism. Found in plastics, cosmetics, and food p...
11/26/2025

Endocrine disruptors are chemicals that interfere with hormones and metabolism. Found in plastics, cosmetics, and food packaging, they can mimic or block natural hormones. Over time, exposure can contribute to obesity, thyroid disorders, and reproductive issues. This article explores their impact and offers practical steps for protection through personalized, holistic care.

↘ What Are Endocrine Disruptors?
↘ How They Interfere with Hormonal Signaling
↘ Health Effects: Subtle but Significant
↘ Quick Summary Table
↘ Patient Case Variations
↘ How to Reduce Exposure
↘ The Broader Context
↘ When to Seek Evaluation
↘ A Common-Sense Approach to Prevention

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Dr. Tashko explains how endocrine disruptors affect hormones and metabolism, and how to reduce exposure through simple, science-based steps.

The APOE gene influences how the brain manages cholesterol and repair. This article explains how each APOE combination, ...
11/24/2025

The APOE gene influences how the brain manages cholesterol and repair. This article explains how each APOE combination, E2, E3, and E4, affects dementia risk, what other genes may contribute, and how age and lifestyle determine outcomes. This article highlights a holistic and metabolic approach that helps protect the brain even in higher-risk individuals.

↘ Understanding the APOE Gene
↘ How Often Does APOE Alone Cause Dementia?
↘ Risk by Genotype
↘ When Does APOE4 Risk Become Significant?
↘ Other Genes Linked to Dementia
↘ Genes Are Not Destiny
↘ Clinical Examples
↘ Key Points at a Glance
↘ The Broader View

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Dr. Tashko explains how APOE genotypes influence dementia risk, age of onset, and how metabolic and lifestyle care can change outcomes.

Rome built its latifundia through conquest, public land, and enslaved labor. These estates expanded as small farmers los...
11/24/2025

Rome built its latifundia through conquest, public land, and enslaved labor. These estates expanded as small farmers lost their plots after long wars. Wealth flowed upward while displaced citizens crowded cities. Inequality deepened and political tension followed. The latifundia strengthened elite control and shaped economic patterns that later influenced medieval Europe.

↘ Latifundia: Core Dynamics at a Glance
↘ Origins in Conquest and Public Land
↘ After the Punic Wars: Displacement of Small Farmers
↘ The Role of Slavery and Unequal Wealth
↘ Political Instability and the Fall of the Republic
↘ Legacy Beyond Rome

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Dr. Tashko explores Rome’s latifundia system, showing how vast estates reshaped agriculture, politics, inequality, and Europe’s later feudal order.

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