
Risks of deep vein thrombosis, pulmonary embolism, and bleeding after covid-19: nationwide self-controlled cases series and matched cohort study
Coronavirus Update 5/6/22 - Blood Clots after Covid
BTHO Covid-19
Good news Covid numbers are way down along with deaths and hospitalizations. In fact most cases of Covid we are seeing now only have mild to moderate symptoms. However, there are still some things to be careful of. Personally, now it is these types of complications that concern me much more than Covid itself. A little over two years ago I first wrote about suspecting that Covid is an endothelial disease and can cause clots. Since that time I have suggested that taking a baby aspirin is recommended unless you have a specific contraindication to aspirin use.
Well now multiple studies are showing that people with Covid are at a much higher risk of developing blood clots for many months after they have recovered from Covid. In this study I linked below in British Medical Journal they found that compared with the control period, incidence rate ratios were significantly increased 70 days after covid-19 for deep vein thrombosis, 110 days for pulmonary embolism. This makes clinical sense because typically you get a deep vein thrombosis prior to getting a pulmonary embolism as most pulmonary embolisms are DVT’s that break loose and go to the lungs. Pulmonary embolisms are extremely dangerous and are considered a medical emergency. Incidentally, there was also an increased risk of bleeding for up to 60 days.
This correlates to what we are seeing in the clinics. There has been a substantial increase in the number of deep vein thrombosis we are diagnosing since Covid began. While in this study they found the risk to be highest in patients with severe Covid-19, I personally have seen deep vein thrombosis and even pulmonary embolisms in patients who had only mild Covid symptoms previously.
It should also be mentioned that diagnosing a deep vein thrombosis or even a pulmonary embolism is a difficult diagnosis to make. Many patients do not have significant symptoms until it is too late. So there is likely a significant number of undiagnosed DVT unaccounted for in these numbers.
So what should you look for to protect yourself from being a statistic? Remember that clots are also causes of heart attacks and strokes. So you should monitor for signs of clots, pulmonary embolism, stroke or heart attack:
* Facial drooping
* Weakness or numbness of one arm or leg
* Slurring your speech
* New swelling, tenderness, pain or discoloration in your legs
* Sudden shortness of breath
* Shortness of breath with exercise. If you can’t do things you used to be able to do then see your doctor or go to ER
* Chest pain or pain radiating to the neck, arms, jaw or back
* Coughing up blood
* Racing or irregular heart beat
* Low blood pressure, dizziness or fainting
Call 911 or go to the Emergency Room if you’re experiencing any concerning symptoms. Do not ignore these symptoms as they are potentially life threatening.
In light of this I think it is reasonable to consider using a baby 81mg aspirin for at least 3-4 months after Covid unless you have a contraindication to its use. In addition CoQ10 and NAC have potential anticoagulation properties and should also be considered. You should also stay active as the more your blood circulates the less likely it is to form a clot. When you are sitting, put your legs up as this helps prevent clots too. Remember there are also many other risk factors for DVT’s and PE’s such as hormone therapy, recent surgery, cancer, obesity, clotting diseases, lung and heart disease just to name a few. If you have additional risk factors for clots you should take extra precautions and be aware of the warning signs we mentioned above.
https://www.bmj.com/content/377/bmj-2021-069590
Here is a repost of the supplements we have discussed to have potential benefits.
Quercetin from 250mg up to 1g twice per day Remember this is a Zinc ionophore.
Vitamin D3 Take this for sure if you are deficient and I now recommend taking it either daily or weekly as long as your values are not too high. Remember too much vitamin D can cause issues. However, if you are diagnosed with Covid-19 take 50,000IU immediately as this appears to have significant benefits.
Sleep greater than 8 hours per night
CoQ10 100-300mg per day: a potent antioxidant that potentially helps balance oxidative stress, increase vasodilation, prevent clot formation and decrease vasoconstriction.
Zinc any amount is probably good but take what you can tolerate without making you feel bad up to 40mg. You do not want to be Zinc deficient as it is how many drugs like HCQ work.
Melatonin 0.1mg to 10mg at night. Take what you can tolerate and what helps you sleep without making you feel drugged or tired in the morning. If you are diabetic watch your sugars.
N-acetylcysteine (NAC) - 600mg twice per day shown to decrease severity of influenza, improve lung functions in COPD, antioxidant properties, potentially helps prevent clotting and with mental disorders. Caution for asthmatics as there is potential for bronchospasm but this is rare.
Vitamin C 250mg to 500mg twice per day. Effects debatable in oral form but IV did help in China. But is proven to strengthen immune system
Green Tea either drink some or 1 pill per day alternate zinc ionophore if you don’t have or don’t take Quercetin
Famotidine 10-20mg twice per day potentially inhibits viral replication and helps with heartburn
Baby Aspirin 81mg aspirin to thin blood and help prevent clots but only after discussing with your physician to make sure you have no contraindications to its use.
As always the information and understanding of COVID-19 is changing rapidly. This information is for education purposes only and you should never make changes to your health without consulting your personal physician. Make a virtual appointment with your physician and discuss your health and the best possible treatment plan for you. It is also important to reiterate that there are no clinically evidence-based integrative prevention or treatment strategies for COVID-19 infection.
Let’s all keep praying for all that are ill with this virus in the world.
Gig’em!
Risks of deep vein thrombosis, pulmonary embolism, and bleeding after covid-19: nationwide self-controlled cases series and matched cohort study Objective To quantify the risk of deep vein thrombosis, pulmonary embolism, and bleeding after covid-19. Design Self-controlled case series and matched cohort study. Setting National registries in Sweden. Participants 1 057 174 people who tested positive for SARS-CoV-2 between 1 February 2020 an...