12/05/2025
What are the short-term and long-term benefits of exercise on the brain?
Overall, we have a good understanding of the benefits of exercise on the entire body, including increases in cardiorespiratory function, muscle and joint strength, and immune system function. Collectively, these benefits decrease our chances of developing certain diseases. The one organ we still don’t have the best understanding of during exercise is the brain. The brain is our most metabolically active organ, which is constantly changing as we learn and complete new tasks. But does exercise influence the function of this organ? Research is showing that it does, but the benefits vary depending on the intensity, frequency, acute vs. chronic, duration, and mode of exercise.
Short-Term Benefits:
Minor changes in blood flow - A slight increase that is not intensity dependent.
Increase in blood distribution - Increases oxygenation in the brain.
Increase in glucose uptake - The brain requires more fuel during exercise, which leads to a higher glucose consumption. This effect changes depending on intensity. The higher the intensity, the more lactate is used instead.
Releases endorphins - The exercise high people feel during and after exercise.
Increase in brain-derived neurotropic factor (BDNF) - Important for learning, regulating, and maintaining neuron growth.
Long-term Benefits: Limited experimental evidence in humans, but some results have shown
Possible increase in capillarity
Possible increase in neurogenesis - Creating new neurons.
Possible increase in mitochondrial biogenesis - Increases in the number and mass of the mitochondria in the cell.
Although current research is limited on the benefits of exercise on the brain, the current literature shows that exercise could improve learning and the growth of neurons. These findings provide yet another compelling reason to incorporate regular physical activity into daily life.