NEXT Oncology strives to provide exceptional care, the latest cancer treatments, and a community devoted to finding a cure.
08/27/2025
Don't miss this learning opportunity at the 2025 Summit for Novel Therapeutics in Oncology & Precision Medicine in Cancer (STOP Cancer), featuring Anthony Tolcher and Shiraj Sen!
ICYMI:We’re proud to announce that results from a Phase 1 clinical trial led by Ildefonso Rodriguez-Rivera have been published in Nature Medicine. The study evaluated precemtabart tocentecan (precem-TcT) in collaboration with EMD Serono, Inc. in patients with metastatic colorectal cancer and showed encouraging early activity and manageable safety.
This publication reflects our continued commitment to advancing first-in-human cancer research and improving outcomes for patients with limited treatment options.
Phase 1 trial findings published in Nature Medicine show promise for a new approach to targeting colorectal cancer and other tumors expressing CEACAM5. NEXT Oncology’s Dr. Ildefonso Ismael Rodriguez Rivera, a medical oncologist and hematologist in the San Antonio office, has led an innovative Phas...
08/07/2025
We’re proud to announce that results from a Phase 1 clinical trial led by Ildefonso Rodriguez-Rivera have been published in Nature Medicine. The study evaluated precemtabart tocentecan (precem-TcT) in collaboration with EMD Serono, Inc. in patients with metastatic colorectal cancer and showed encouraging early activity and manageable safety.
This publication reflects our continued commitment to advancing first-in-human cancer research and improving outcomes for patients with limited treatment options.
We were thrilled to celebrate the opening of our newest location in Houston with a fun Grand Opening party.
06/09/2025
Congratulations to our colleagues at Iambic Therapeutics for continued success. Our own Andrae Vandross with NEXT - Austin had this to say: “Patients entering this study, particularly those with brain metastases, have few available treatment options. Our focus is on identifying important potential advances for these individuals and to look at novel approaches that may provide a therapeutic benefit.”
Read more here:
Designed with Iambic’s AI-Drug Discovery platform, IAM1363 is highly differentiated by its target selectivity, brain-penetrance, pan-mutant activity, and tumor enrichment
06/02/2025
We are very honored to support ongoing clinical research at American Society of Clinical Oncology (ASCO) 2025 and the Merit awards. Congratulations to Curtis Perry, recipient of the Anthony and Marilyn Tolcher Merit award and Udhayvia Grewal, recipient of the Theresa Mays Endowed Merit Award, for their outstanding work.
05/28/2025
Congratulations to our colleagues at Biohaven on continuing to advance innovative . Our own Michael Song commented: "We are excited to partner with Biohaven and dose the first patient on this important study. This is an exciting, validated target with potential to extend therapeutic benefit to several FGFR3 driven tumors."
Read more here:
05/20/2025
We are thrilled to announce that our colleague Alex Spira, MD, PhD, FACP, FASCO with NEXT Oncology Virginia has been appointed Chief Scientific Officer for NEXT Oncology worldwide.
Our founder, Anthony Tolcher, had this to say: “We are committed to offering hope when conventional treatments fall short—and that’s what being the NEXT Option is all about. Dr. Spira is a respected leader in the oncology community, and his expertise will be instrumental as we expand our Phase 1 trial capabilities and scientific leadership.”
At NEXT Oncology, we work with companies like Tagworks Pharma to research the NEXT Option in cancer therapies.
Tagworks initiates Phase 1 trial for TGW101, a first-in-class Click-to-Release ADC targeting TAG-72, and appoints Dr. Keith Orford as Chief Medical Officer.
April is Esophageal Cancer Awareness Month. The statistics surrounding esophageal cancer are truly alarming, which makes awareness and education so important. This April, take a few minutes to learn the facts about esophageal cancer and become familiar with the symptoms and risk factors. It could be life-saving information for you or someone you love.
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Our mission is to transform the industry though the development of the next breakthrough in cancer research through high quality Phase 1 clinical pharmacology trials.
NEXT Oncology, founded by Anthony W. Tolcher, M.D., FRCPC, is a Phase 1 center dedicated to providing options for advanced cancer patients and advancing cancer research. Dr. Tolcher’s passion for research and the community lays the foundation for an international brand committed to finding the next breakthrough.
Dr. Anthony Tolcher is a medical oncologist and co-founder of NEXT. He is dedicated to the development of new anticancer agents for patients whose current cancer therapy is no longer working to benefit them and are looking for their next option that includes clinical trials of new agents and therapies. Dr. Tolcher is proud that at NEXT Oncology the team scours the world to bring the best new agents back to our patients and centers.
This is not a job for Dr. Tolcher, it is his passion.
"We are going to make cancer treatable or curable in my lifetime." Read more from Dr. Tolcher in the recent article written by WOAI.