Gladstone Institutes

Gladstone Institutes To drive a new era of discovery in disease-oriented science and to mentor tomorrow’s leaders in an Learn more at gladstone.org
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Gladstone is an independent, nonprofit life science research organization located in the epicenter of biomedical and technological innovation in the San Francisco Bay Area. Gladstone has created a research model that disrupts how science is done, funds big ideas, and attracts the brightest minds. Vision
To overcome unsolved diseases through transformative biomedical research. Mission
To drive a ne

w era of discovery in disease-oriented science and to mentor tomorrow’s leaders in an inspiring and diverse environment.

Collaboration between computational and experimental scientists is driving discovery in powerful new ways. What’s one sc...
05/26/2026

Collaboration between computational and experimental scientists is driving discovery in powerful new ways.

What’s one scientific breakthrough or innovation you think became possible because of collaboration?

Breakthroughs don’t happen by playing it safe. At Gladstone, we dare to take risks by exploring the unknown, pursuing am...
05/25/2026

Breakthroughs don’t happen by playing it safe.

At Gladstone, we dare to take risks by exploring the unknown, pursuing ambitious ideas, and challenging conventional thinking. We believe curiosity fuels innovation—and that failure can be an essential step toward discovery and progress.

Bold science starts with the courage to try something new.

05/24/2026

Meet the people behind the science.

In this clip Alisa Dietl, postdoctoral scholar, shares how the biggest influence on her scientific career has been her patients.

Feeling the frustration of not being able to offer a promising treatment—let alone a cure—pushed her toward research, where she can reach more patients and help shape the future of their care as a clinician-scientist

For decades, scientists have studied how HIV infects the human body—but many questions have remained unanswered. Now, re...
05/23/2026

For decades, scientists have studied how HIV infects the human body—but many questions have remained unanswered. Now, researchers at Gladstone Institutes and UCSF have created the first comprehensive genetic roadmap showing how HIV interacts with real human cells.

Published in Cell, the study identified human proteins that either help the virus survive or work to stop it, opening new possibilities for understanding—and eventually targeting—HIV infection.

This work offers an unprecedented look at the complex battle between HIV and the cells it hijacks.

Read more at the link in the comments.

  to when Gladstone researchers introduced CellWalker2—a powerful computational tool designed to bring clarity to comple...
05/23/2026

to when Gladstone researchers introduced CellWalker2—a powerful computational tool designed to bring clarity to complex single-cell data. 🧩🔬

Led by Katie Pollard and Zhirui Hu, the tool helps scientists uncover relationships between cell types across tissues, studies, and even species, opening new possibilities for understanding diseases like autism, schizophrenia, and heart disease.

Link in comments to read more about this study.

05/22/2026

We're currently accepting nominations for the 2026 Ogawa-Yamanaka Stem Cell Prize.

In this clip, Deepak Srivastava shares how the Ogawa-Yamanaka Prize has become one of the world's most significant stem cell awards.

This flagship scientific event at Gladstone recognizes groundbreaking stem cell research, and is held in partnership with Cell Press.

Link in comments to learn how to submit a nomination.

Women’s health research has long been overlooked and underfunded—but scientists like Gladstone’s Barbara Engelhardt are ...
05/21/2026

Women’s health research has long been overlooked and underfunded—but scientists like Gladstone’s Barbara Engelhardt are helping move the field forward. Engelhardt is leading menstrual-cycle research aimed at collecting biometric data from more diverse populations while carefully considering participant privacy and data security.

Her work is featured in this San Francisco Business Times story on the growing push to advance women’s health research and improve how we understand health and disease.

Stanford researchers are navigating complex ethical and political issues to study women's health. Even finding the right wearable device has been fraught.

We want to hear from you! 🧪 What topics would you like our scientists to dive deeper into?Leave a comment and let's star...
05/20/2026

We want to hear from you! 🧪 What topics would you like our scientists to dive deeper into?

Leave a comment and let's start the conversation!

05/20/2026

A new genetic roadmap reveals hundreds of hidden players in infection, including two proteins that stop HIV in its tracks.

Link in comments to read more about this study 👇 👇

How do brain cells change with age? How are liver cells impacted when someone takes a new medicine? What happens to lung...
05/19/2026

How do brain cells change with age? How are liver cells impacted when someone takes a new medicine? What happens to lung cells after decades of smoking?

Scientists are using AI to answer these questions.

05/18/2026

Imagine taking a teaspoon of blood or a small skin sample—and turning those cells back in time. In this short animated explainer, Gladstone President Deepak Srivastava walks through the groundbreaking science of cellular reprogramming, where just four proteins can transform adult cells into induced pluripotent stem (iPS) cells which are capable of becoming any cell type in the body.

These reprogrammed cells not only hold the potential to repair damaged tissues and treat disease, but also allow scientists to study genetic conditions in a dish—uncovering why cells malfunction and how new or existing drugs might fix them.

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