Gladstone Institutes

Gladstone Institutes To drive a new era of discovery in disease-oriented science and to mentor tomorrow’s leaders in an Learn more at gladstone.org
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Gladstone is an independent, nonprofit life science research organization located in the epicenter of biomedical and technological innovation in the San Francisco Bay Area. Gladstone has created a research model that disrupts how science is done, funds big ideas, and attracts the brightest minds. Vision
To overcome unsolved diseases through transformative biomedical research. Mission
To drive a new era of discovery in disease-oriented science and to mentor tomorrow’s leaders in an inspiring and diverse environment.

10/28/2025

Nobel Prize-winning scientist Shinya Yamanaka shares the deeply personal and touching story behind the prestigious Ogawa-Yamanaka Stem Cell Prize.

In this emotional short, Yamanaka reveals how his close friends and mentors, Hiro and Betty Ogawa, created this scientific prize.

You can join us online for the 2025 Ogawa-Yamanaka Stem Cell Prize Ceremony. Learn more: https://bit.ly/4gNhf3z

Shijie Wang, a postdoctoral scholar in Steve Finkbeiner’s lab, uses artificial intelligence, robotics, and stem cell tec...
10/27/2025

Shijie Wang, a postdoctoral scholar in Steve Finkbeiner’s lab, uses artificial intelligence, robotics, and stem cell technologies to uncover how brain cells die in neurodegenerative diseases like Alzheimer’s and Parkinson’s.

Winners of this year's Outstanding Mentor Award, share their insights on the importance of mentorship, their approach to...
10/27/2025

Winners of this year's Outstanding Mentor Award, share their insights on the importance of mentorship, their approach to mentoring, and how being a mentor has impacted and shaped their careers.

The three awardees of the Outstanding Mentoring Award share their insights on the transformative power of mentorship in shaping the next generation of scientists.

In a stunning leap forward for immunotherapy, researchers from the Arc Institute, Gladstone, and UCSF have unveiled a gr...
10/26/2025

In a stunning leap forward for immunotherapy, researchers from the Arc Institute, Gladstone, and UCSF have unveiled a groundbreaking epigenetic editing platform that redefines the genetic programming of human T cells.

In a stunning leap forward for immunotherapy, researchers from the Arc Institute, Gladstone Institutes, and the University of California, San Francisco have unveiled a groundbreaking epigenetic

Gladstone researcher Isha Jain has received an award from the NIH to advance vitamin biology. 👩‍🔬
10/26/2025

Gladstone researcher Isha Jain has received an award from the NIH to advance vitamin biology. 👩‍🔬

Dr. Isha Jain has been awarded the prestigious NIH Tran […]

Rolling up your sleeve for your flu shot or COVID booster this fall? 💪Turns out, those vaccines might be doing more good...
10/25/2025

Rolling up your sleeve for your flu shot or COVID booster this fall? 💪

Turns out, those vaccines might be doing more good than you realize.
Gladstone virologist Melanie Ott explains the unexpected positive side effects of vaccines.

Learn more 👇 👇

Melanie Ott talks about the ongoing measles outbreak, explains how vaccination can lower the risk of Alzheimer’s, and shares other positive “side effects” of vaccines.

The California Institute for Regenerative Medicine has just awarded $7.5 million in discovery grants to Gladstone scient...
10/25/2025

The California Institute for Regenerative Medicine has just awarded $7.5 million in discovery grants to Gladstone scientists, fueling innovative research in gene editing, stem cells, and disease-mechanism discovery.

Read how this funding could break open new paths to cures 👉 https://bit.ly/3W2e7HB

10/24/2025

Durable reprogramming of human T cells may now be possible thanks to a new technique based on the CRISPRoff and CRISPRon methodology.

Researchers from the Arc Institute, Gladstone, and UCSF have stably silenced or activated genes in this type of immune cell without cutting or altering its DNA, making T cells more resistant, active, and effective against tumors.

The link between an extra copy of chromosome 21 and Down syndrome has been well established for decades. What has not be...
10/23/2025

The link between an extra copy of chromosome 21 and Down syndrome has been well established for decades. What has not been clear was the genetic basis for the congenital heart defects that are associated with nearly half of babies born with Down syndrome.

Now, a new study describes how HMGN1 disrupts DNA’s packaging and regulation and how this impacts molecular levels in healthy heart development.

Results suggest that increased expression of the HMGN1 gene is necessary for the cardiac defects observed in patients.

10/23/2025

In our new animated explainer, Visualizing Stem Cell Therapy, Deepak Srivastava shares how stem cell discoveries are transforming medicine.

After decades of mystery, Gladstone researchers identify a gene that can derail heart formation.
10/22/2025

After decades of mystery, Gladstone researchers identify a gene that can derail heart formation.

After decades of mystery, Gladstone researchers identify a gene that can derail heart formation—and show that fixing it prevents the problem in mice.

As we get ready for the upcoming 2025 Ogawa-Yamanaka Stem Cell Prize ceremony, Deepak Srivastava shares how the prize ha...
10/21/2025

As we get ready for the upcoming 2025 Ogawa-Yamanaka Stem Cell Prize ceremony, Deepak Srivastava shares how the prize has become one of the world's most significant stem cell awards.

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