Cureus Journal of Medical Science

Cureus Journal of Medical Science The Open Access medical journal for a new generation of doctors, researchers and patients. Cureus currently recognizes the following medical specialties.
(2)

Don’t see your specialty listed? Contact us at support@cureus.com. A
Allergy and Immunology
Anatomy
Anesthesiology
C
Cardiac/Thoracic/Vascular Surgery
Cardiology
Critical Care
D
Dentistry
Dermatology
Diabetes and Endocrinology
E
Emergency Medicine
Epidemiology and Public Health
F
Family Medicine
Forensic Medicine
G
Gastroenterology
General Practice
Genetics
Geriatrics
H
Health Policy
Hematology
HIV/AIDS
Hospital-based Medicine
I
Infectious Disease
Integrative/Complementary Medicine
Internal Medicine
Internal Medicine-Pediatrics
M
Medical Education and Simulation
Medical Physics
N
Nephrology
Neurological Surgery
Neurology
Nuclear Medicine
Nutrition
O
Obstetrics and Gynecology
Occupational Health
Oncology
Ophthalmology
Optometry
Oral Medicine
Orthopaedics
Osteopathic Medicine
Otolaryngology
P
Pain Management
Palliative Care
Pathology
Pediatrics
Pediatric Surgery
Pharmacology
Physical Medicine and Rehabilitation
Plastic Surgery
Podiatry
Preventive Medicine
Psychiatry
Psychology
Pulmonology
R
Radiation Oncology
Radiology
Rheumatology
S
Substance Use and Addiction
Surgery
T
Therapeutics
Trauma
U
Urology

11/24/2025

This Cureus article challenges some of the most common myths in infectious disease care:
Myth 1: Bactericidal drugs are always better than bacteriostatic ones.
Fact: Randomized trials show no consistent advantage, some infections even respond better to bacteriostatic agents.
Myth 2: Every fever needs a urine culture.
Fact: Indiscriminate testing leads to unnecessary antibiotics for false-positive results.
Myth 3: Longer antibiotic courses prevent resistance.
Fact: Evidence says the opposite- shorter, targeted treatments reduce resistance risk.

The takeaway?
Antibiotics remain life-saving but only when used with precision, not reflex.

Read the open-access article →https://hubs.la/Q03VwyvG0

Coronary artery bypass grafting (CABG) saves lives, but it also triggers a storm of oxidative stress, which can lead to ...
11/24/2025

Coronary artery bypass grafting (CABG) saves lives, but it also triggers a storm of oxidative stress, which can lead to complications like atrial fibrillation, kidney injury, and graft failure.

This Cureus review explores how aminothiols; molecules like glutathione, homocysteine, cysteine, and cysteinylglycine, help maintain the body’s redox balance and could serve as biomarkers for recovery after CABG.

Key insights:
Glutathione protects against oxidative damage.
Homocysteine elevation worsens inflammation and outcomes.
Cysteine and cysteinylglycine reflect redox shifts during surgery.
Advanced lab tools like LC-MS and HPLC can measure them precisely, though standardization is still a challenge.

Therapies such as N-acetylcysteine and folate may help restore balance, but more research is needed to turn these findings into personalized post-surgery care.

Could tracking these molecules one day guide real-time recovery after bypass surgery?

Read more here: https://hubs.la/Q03VwyvJ0

A 38-year-old man with mild reflux and no major symptoms suddenly developed severe chest pain and shortness of breath af...
11/23/2025

A 38-year-old man with mild reflux and no major symptoms suddenly developed severe chest pain and shortness of breath after eating pizza.
Scans revealed something unexpected; a spontaneous esophageal perforation, caused by previously undiagnosed eosinophilic esophagitis (EoE).

EoE is an immune-driven inflammation of the esophagus that’s becoming increasingly common. While it often causes mild swallowing difficulty or heartburn, it can stay silent; until it leads to a catastrophic tear.

Through endoscopic and surgical repair, endoluminal vacuum therapy, and careful multidisciplinary management, this patient made a full recovery.

This case is a reminder that EoE can mimic simple reflux but carries the risk of sudden, life-threatening complications if left undiagnosed.

Read more here: https://hubs.la/Q03SM2DL0

This Cureus study evaluated 49 Latino patients who underwent implantation of the Apthera™ small-aperture extended depth ...
11/22/2025

This Cureus study evaluated 49 Latino patients who underwent implantation of the Apthera™ small-aperture extended depth of focus intraocular lens (IOL); the first of its kind studied in this population.

Results after surgery were promising:
Near vision (UNVA) improved dramatically in the Apthera™ eye, from 0.71 to 0.12 LogMAR at six months.
Distance vision (UDVA) improved in the fellow eye as expected.
Refraction remained stable and predictable, with slightly more myopic outcomes in the Apthera™ eye, supporting precision targeting.
Astigmatism showed a mild residual trend but did not significantly affect outcomes.

The takeaway: The Apthera™ IOL offers reliable, enhanced visual performance and refractive stability in Latino patients, aligning with U.S. FDA clinical data, marking an important step toward more inclusive ophthalmic research.

Read more here: https://hubs.la/Q03Vb4540

A 54-year-old man came to the hospital with progressive weakness and numbness in his right leg; simple symptoms that mad...
11/21/2025

A 54-year-old man came to the hospital with progressive weakness and numbness in his right leg; simple symptoms that made walking difficult.
But MRI of his spine revealed something unexpected: intramedullary spinal cord metastases (ISCM); cancer that had spread inside the spinal cord itself.

Further scans uncovered a lung adenocarcinoma, confirmed by biopsy. Despite chemotherapy and radiotherapy, he passed away two months later.

This case underscores the importance of considering metastatic disease in patients with new, unexplained neurological symptoms; especially when weakness or sensory loss develops rapidly.

Read more here: https://hubs.la/Q03SLXW50

Black Salve; an unregulated escharotic paste sold online, is often promoted as a natural alternative to surgery for remo...
11/20/2025

Black Salve; an unregulated escharotic paste sold online, is often promoted as a natural alternative to surgery for removing moles or skin cancers.
But what actually happens when patients try it?

This Cureus case describes a patient who self-treated a basal cell carcinoma (BCC) with Black Salve and meticulously documented the entire process.

The result offered a rare, detailed look into how these corrosive agents destroy tissue; sometimes removing the tumor, but often causing disfigurement, delayed diagnosis, and incomplete cancer clearance.

This case underscores the need for education, empathy, and early medical consultation when patients choose alternative therapies for potentially malignant lesions.

Read more here: https://hubs.la/Q03SLQ3J0

Bring Your Research to Life with Video AbstractsWant your research to capture attention? Cureus invites authors to creat...
11/19/2025

Bring Your Research to Life with Video Abstracts

Want your research to capture attention? Cureus invites authors to create video abstracts dynamic, visual summaries that highlight your findings in a captivating way. Our guide walks you through every step, from scripting to submitting, ensuring your work makes a memorable impact.

Explore the guide and elevate your research:
https://hubs.la/Q03V1SZ40

In emergency abdominal surgeries, especially for perforation peritonitis, infection risk is extremely high, even with an...
11/19/2025

In emergency abdominal surgeries, especially for perforation peritonitis, infection risk is extremely high, even with antibiotics. This randomized controlled trial tested whether hypochlorous acid (HOCl), a powerful yet biocompatible antimicrobial, could make a difference when used as an intraoperative lavage.

Among 148 patients, those who received HOCl lavage had half the infection rate of the saline group (20.3% vs. 39.2%); and showed faster wound healing (79% vs. 50% by day 15). By day 30, every HOCl-treated wound had healed completely, with no adverse effects or resistant bacteria reported.

The takeaway?
Sometimes innovation isn’t a new drug, it’s a smarter way to use an old molecule.

Read more here: https://hubs.la/Q03SLTgM0

Quitting Ni****ne? Don’t Go “Cold Turkey” AloneKicking the habit can get uncomfortable and abrupt withdrawal may bring u...
11/18/2025

Quitting Ni****ne? Don’t Go “Cold Turkey” Alone

Kicking the habit can get uncomfortable and abrupt withdrawal may bring unexpected surprises. This case report reveals how sudden ni****ne cessation can trigger unusual reactions like cold turkey Russian-style: adverse cardiovascular and psychological symptoms following gum-based abrupt ni****ne withdrawal.

Read more:
https://hubs.la/Q03TMSDm0

****neWithdrawal

Service Outage UpdateWe’re currently experiencing a temporary outage and our team is already on it. We’ll share another ...
11/18/2025

Service Outage Update

We’re currently experiencing a temporary outage and our team is already on it. We’ll share another update as soon as everything is back up and running.

Thank you for your patience.

11/18/2025

Why do clinicians and researchers choose Cureus Journal of Medical Science, part of Springer Nature?

In this episode of the Why I Chose Cureus: Author Spotlight Series, Dr. Jomar N. Machuca, Internal Medicine Specialist from Puerto Rico and Cardiac Amyloid Fellow at MUSC, shares reflections on his experience publishing multiple cardiovascular articles with Cureus.

Dr. Machuca highlights:
Efficient, constructive peer review that strengthens manuscripts
Fast publication timelines - weeks, not months
Gold open access, ensuring immediate global visibility
A credible, clinician-friendly platform for sharing impactful medical knowledge

For researchers, fellows, and clinicians seeking accessibility, transparency, and global reach, Cureus offers a supportive space to share work that advances practice and improves patient care.

His published contributions include:
From Strep Infection to a Strepitous Heart Pattern in Rheumatic Fever: A Case Report
Cardiovascular Disease in Women and the Role of Hormone Replacement Therapy (Review Article)
Cardiac Angiosarcoma Presenting as Large Pericardial Effusion With Effusive-Constrictive Pericarditis

Want to be featured in this series? View the video recording guide and submit your spotlight: https://hubs.ly/Q03TK9tq0

A 72-year-old man with type 2 diabetes mellitus (T2DM) and portal vein thrombosis (PVT) was treated with heparin and war...
11/16/2025

A 72-year-old man with type 2 diabetes mellitus (T2DM) and portal vein thrombosis (PVT) was treated with heparin and warfarin to dissolve the clots.

Within just 1–2 weeks, something unexpected happened; his blood glucose began to normalize. To avoid hypoglycemia, his antidiabetic medications were gradually reduced from three to none, yet his glucose levels remained steady between 90–120 mg/dL.

Follow-up imaging showed partial resolution of both PVTs and aortic thrombi, and his diabetes remained controlled even without medication.

This Cureus case report raises a fascinating question: Could anticoagulant therapy have metabolic effects beyond clot prevention; or reveal a new pathway linking coagulation and glucose regulation?

Read more here: https://hubs.la/Q03SLK1F0

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