The Epi Center MedSpa

The Epi Center MedSpa The nation’s first MedSpa. Awarded Top MedSpa in the US. Visit our website for more details, to receive a $50 gift card and to schedule your free consultation.

We are a refuge for skin rejuvenation and renewal, providing a luxurious guest experience and the latest in skincare treatments. By combining medical grade products, our custom treatment programs achieve natural, lasting results in a soothing, eco-friendly environment. Our staff includes top nurse practitioners, physician assistants, registered nurses and licensed aestheticians with on-site superv

ision by medical doctors, working together so you achieve maximum results. We offer Botox, CoolSculpting, Microneedling, Laser Hair Removal ,PhotoFacial, PDO Nova Threads, Dermatology exams, Skin Tightening, Pixel Resurfacing, Restylane, Sculptra, Juvederm, Voluma, Botox and Dysport, Volume Lift, High-Speed Laser Hair Removal, Acne Treatments, Weight Loss Plans, Vitamin B Shots, Coolsculpting Suite, Cellulite Treatments, Microneedling with GH, Tattoo Removal, HydraFacial MD, Facials and more. Our specialized treatments correct sun damage, uneven pigmentation, brown and age spots, facial redness and rosacea, acne and acne scars, skin texture and tightening, facial lines and wrinkles, under eye rejuvenation, weight reduction and spider leg veins. We have been recognized at best Botox, best Laser Hair Removal, best CoolSculpting, best Microneedling and best PhotoFacial treatments in the Bay Area.

Happy Birthday, Dr. B! 🎉 on this special day, we celebrate you — our visionary Medical Director, renowned dermatologist,...
05/16/2026

Happy Birthday, Dr. B! 🎉

on this special day, we celebrate you — our visionary Medical Director, renowned dermatologist, and the brilliant creator of the IPL/Photofacial℠. We are so fortunate and deeply grateful to have your steady hand and extraordinary expertise guiding our team at the helm.
Thank you for your wisdom that inspires us, your ingenuity that transforms lives, your medical genius that sets the highest standard, and for the countless ways you elevate every person around you. Your passion and dedication continue to light the way for all of us.
Wishing you the most joyful, fulfilling, and wonderful birthday ever — filled with celebration, laughter, and all the happiness you so richly deserve.
We love you, Dr. B!
With immense admiration and gratitude,
Margaret Mitchell
CEO/Founder
and the entire Team Epi

05/11/2026

Happy Mother’s Day to every single one of you beautiful souls who wear the title of “Mom” — in any way, shape, or form. 💐
To the moms who gave us life,�the stepmoms who chose us and loved us anyway,�the grandmoms who spoil us rotten and tell the best stories,�the heavenly moms watching over us with angel wings and endless love,�the godmoms, aunties, foster moms, bonus moms, mother figures, fur moms, and every woman who shows up with a mother’s heart…
Thank you.�Thank you for the midnight cuddles, the tough love, the scraped-knee kisses, the prayers, the sacrifices we’ll never fully know, and the quiet strength that held us together when the world felt heavy.
You didn’t just raise children — you raised hope, kindness, courage, and generations who are better because you existed.
Today we celebrate YOU — all of you.�You are seen. You are loved. You are irreplaceable.
Happy Mother’s Day from the bottom of our hearts. ❤️

04/24/2026

✨ Sofwave has officially landed at ✨
The ultimate lunchtime lift is here! In just 45-60 minutes with zero downtime, this breakthrough treatment delivers immediate tightening and gorgeous texturizing results.
Powered by next-generation SUPERB™ ultrasound technology, Sofwave stimulates your body’s natural collagen and elastin for lifted brows, a sharper jawline, smoother neck, and refreshed skin — all without surgery.
This patient had Ultherapy many years ago and loved the gradual results, but brought that instant wow factor she was looking for.
Obsessed with her refreshed jawline and neck glow!
Huge thanks to the dream team .samodeeva for these fabulous results 🔥
Ready for your own Sofwave lunchtime lift?�DM for introductory pricing — spots are going fast!
JawlineGoals

04/24/2026

✨ Before & After Magic with PDGF Ariessence Injections ✨
Obsessed with this snatched jawline transformation! 😍 Look at the smoother texture, reduced redness, tighter contours, and that crisp definition—pure skin goals.
What is Ariessence PDGF?�It’s a cutting-edge regenerative treatment powered by pure platelet-derived growth factor (PDGF). This lab-engineered protein supercharges your skin’s natural repair process—boosting collagen & elastin production, improving firmness, reducing fine lines, and enhancing overall tone and texture. Delivered via precise injections, it delivers next-level rejuvenation without the variability of PRP/PRF.
Huge thanks to .samodeeva and for these incredible results! 🙌
Ready to sculpt and glow? Book your consultation at 💉

04/11/2026

Come relax with our red light therapy, deluxe steam hydrafacial & scalp massage 🧖‍♀️ ̇al

04/05/2026

HAPPY EPIVERSARY!

🎉✨ Today, on April 4, I celebrate the 28th anniversary of Epi Center Medspa, reminiscing about that pivotal day when our first employee started! Can you believe it’s been almost three decades of this incredible journey?

As the first medical spa, I am so proud of the decisions we’ve made that have shaped our industry. I’ll never forget the day I spent with my brilliant partner, Dr. Patrick Bitter Sr. We were literally folding towels when he coined the term “MedSpa.” Such a humble beginning that turned into something global and extraordinary!

Over the years, we’ve had numerous employees, many of whom have gone on to lead fabulous lives, practicing aesthetics across the country. We envisioned a serene space outside the hustle and bustle of a traditional dermatology or plastic surgery office—a place where people could enjoy a relaxing experience with their treatments.

I love you, Dr. B. Thank you for dreaming with me, taking chances, and making this vision a reality together.

And to all our wonderful patients—thank you! With a database of 48,000, you’ve trusted us to be a part of your journey, and for that, I am truly grateful. I’ve spent most of my adult life in this industry, and it has been nothing short of a pleasure and a blessing.

Here’s to many more years of beauty and wellness together! ❤️✨ Always,

03/29/2026

Undereye perfection, without the filler. 🌿💉
PDGF injections stimulate your own collagen, smooth fine lines, and restore that youthful glow. Subtle. Sophisticated. Scientifically-backed. ✨
GlowGoals

03/08/2026

Happy International Women’s Day! 🌸💪
Today, we celebrate the power, resilience, and leadership of women worldwide. Margaret Mitchell, our visionary CEO and Founder, embodies this spirit as the trailblazing force behind Epi Center MedSpa—a proudly women-owned and women-led institution that pioneered the medical spa concept in the nation.
As the first medical spa in the U.S., we’re proudly marking 27 years of innovation, stability, and excellence right in the heart of San Francisco. Our exceptional team weaves together a rich tapestry of diversity, representing 13 different countries and speaking 11 languages, enabling us to connect authentically and provide expert, inclusive care for every skin type and every story.
We are more than a medical spa—we’re a community dedicated to beauty, wellness, empowerment, and redefining aesthetic excellence through compassion and expertise.
In the spirit of , let’s continue lifting each other up: when we invest in women’s leadership, innovation, and care, we all thrive.
Here’s to Margaret and every woman driving change, healing, and beauty—today and always. Thank you for inspiring us!
Join us in celebrating this milestone of diversity, expertise, and women-powered excellence. ❤️✨
WomenInBusiness EpiCenterMedSpa SanFrancisco 27YearsOfExcellence

03/06/2026

✨ Check out this 2-week transformation! A few precise Botox injections by helped soften this gummy smile for a more balanced, confident look. 💉
Results like this are why we love what we do.

03/01/2026

Happy Birthday to our fabulous Botox Queen Inessa! 🎉💉✨Inessa, you are such an integral part of our Epi Center MedSpa team—for an incredible 23 years! Your expertise, warmth, and that signature glow you bring to every client (and to all of us) make every day brighter. Cheers to the best birthday ever, filled with all the love, light, laughter, and maybe a little extra pampering your heart can hold. We love you so much! 🩷 -Team Epi

02/22/2026

Happy Birthday, .rn! 🎉✨
From all of us at Team Epi: Cheers to our amazing aesthetic nurse whose artistry, compassion, precision, and radiant energy transform lives every single day. Your skill with a syringe (and a smile) brings out the best in everyone you touch, and your presence makes our team stronger, kinder, and more beautiful inside and out. May this birthday shower you with pure joy, endless glow, loving moments, sunny escapes, and all the adventures that make your heart light up. We’re beyond grateful you’re part of the Epi family. Here’s to celebrating YOU and the stunning year ahead! 🥂🌸 With so much love and the biggest team hugs,�Team Epi ❤️

Address

450 Sutter Street Rm 800
San Francisco, CA
94108

Opening Hours

Monday 10am - 6:30pm
Tuesday 10am - 6:30pm
Wednesday 10am - 7pm
Thursday 10am - 6:30pm
Friday 10am - 7pm
Saturday 10am - 6:30pm

Telephone

+14153624754

Website

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