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NCIRE - Northern California Institute for Research and Education, Inc.

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NCIRE - Northern California Institute for Research and Education, Inc.

NCIRE – Northern California Institute for Research and Education, Inc. has one mission and one goal: Veterans' Health.

We are the leading nonprofit research institute in the United States devoted to advancing Veterans' health research. Through new technologies, novel scientific insights, and international clinical collaborations, we strive to set a new standard of health care for veterans and military personnel.

01/05/2026

Prevalence of Exposures and Moral Injury in First Responders

Workers in high-stakes occupations, such as first responders, are at risk of exposure to potentially morally injurious events (PMIEs) and moral injury, yet research with first responders has been scarce.

Dr. Shira Maguen’s study, titled “Prevalence of Exposures and Moral Injury in First Responders” aimed to assess the frequency of exposure to PMIEs, the prevalence of moral injury, and the correlation between moral injury and other mental health symptoms.

The study was published in the Journal of the American College or Emergency Physicians Open and can be read here: https://pmc.ncbi.nlm.nih.gov/articles/PMC12547314/

01/01/2026

NCIRE wishes all Veterans, those serving in the military, and their families, a safe and happy holiday season, and a Happy New Year!

12/20/2025

December 20th marks the 6th birthday of the United States’ youngest military branch.

The United States Space Force is a separate and distinct branch of the armed services, organized under the Department of the Air Force in a manner very similar to how the Marine Corps is organized under the Department of the Navy. Its Mission: to organize, train, and equip Guardians to conduct global space operations that enhance the way U.S. joint and coalition forces fight, while also offering decision makers military options to achieve national objectives.

NCIRE wishes the U.S. Space Force a Happy 6th Birthday and thanks its service members for protecting us “Always Above”!
Read more: https://www.spaceforce.mil/

12/13/2025

On December 13th we celebrate the 389th birthday of the U.S. National Guard. On this date in 1636, the first militia regiments in North America organized in Massachusetts. Based upon an order of the Massachusetts Bay Colony’s General Court, the colony’s militia was organized into three permanent regiments to defend the colony better. Today, the descendants of these first regiments – the 181st Infantry, the 182nd Infantry, the 101st Field Artillery, and the 101st Engineer Battalion of the Massachusetts Army National Guard – share the distinction of being the oldest units in the U.S. military. NCIRE celebrates the National Guard and its long history.

Learn more: https://www.nationalguard.mil/

12/12/2025

Dr. Renuka Nayak presents research at American College of Rheumatology conference

Dr. Renuka Nayak had the honor of presenting her research during the annual American College of Rheumatology (ACR) conference “ACR Convergence 2025”, October 24-29 in Chicago, Illinois.

In the October 26th session, titled, “Immune-Metabolite Axis: How Microbial and Host Byproducts Drive Inflammation”, Dr. Nayak discussed therapeutic approaches to treat rheumatoid arthritis (RA) using short-chain fatty acids (SCFA).

Along with her colleagues Dr. Nayak’s research on identical twins who are discordant for RA found that the twin with RA had significantly lower concentrations of f***l butyrate and propionate. SCFA-producing bacteria were also decreased in the RA twin. This suggests that low levels of SCFAs may contribute to the development or progression of RA.

Read more: https://www.acrconvergencetoday.org/experts-to-navigate-shared-pathways-of-immune-gut-axis/

12/09/2025

Utilization of home- and community-based services among rural family caregivers of persons with dementia: the role of the area deprivation index

Dementia significantly impacts rural communities in the U.S., presenting unique challenges for family caregivers due to limited access to essential support services.

Dr. Kenneth Covinsky co-published a study that examines the influence of area-level factors on the utilization of home- and community-based services among rural caregivers.

The study, titled "Utilization of home- and community-based services among rural family caregivers of persons with dementia: the role of the area deprivation index”, was published in the journal Frontiers in Public Health.

Read more:
https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2025.1688161/full

12/08/2025

The Northern California Institute for Research and Education, Inc. (NCIRE) was established in 1988 following Congress passing Public Law 100-322 (now codified at section 7361-66 of title 38, United States Code) that allowed Department of Veterans Affairs (VA) medical centers to establish Nonprofit research corporations (NPCs) to provide flexible funding mechanisms to administer non-VA research funds, forming a unique public/private partnership that dramatically broadened VA’s ability to benefit from private and non-VA public support for research conducted at VA medical centers.

For the past 37 years, NCIRE has grown from a small 4-person team into a bustling 31-person administrative core staff with 215 employees in research labs and offices within the San Francisco VA campus lead by Rebecca Rosales, MBA, CRA, Chief Executive Officer. NCIRE is the largest of the 79 Nonprofit research institutes associated with the Department of Veterans Affairs nationwide and plays a crucial role in supporting nearly 200 SFVAHCS researchers as they endeavor to improve the understanding and management of disorders affecting our Veterans.

Please join us in celebrating 37 years serving Veterans and the global community through research advancement!

www.ncire.org

12/07/2025

Each year on December 7th, Veterans, and visitors from all over the world come together to honor and remember the 2,403 service members and civilians who were killed during the attack on Pearl Harbor on December 7, 1941. An additional 1,178 people were injured in the attack, which permanently sank two U.S. Navy battleships (the USS Arizona and the USS Utah) and destroyed 188 aircraft.

On Pearl Harbor Remembrance Day, NCIRE honors the Veterans and civilians who lost their lives in an attack that changed the course of history.

Read more: https://pearlharbor.org/

12/05/2025

Come and read the latest issue of the NCIRE Details News Awards (DNA) Newsletter: Volume 29 Winter 2025!

Thank you to the contributors, Kelly Wentworth, MD, who shares her research focusing on a rare bone disease – fibrous dysplasia (FD). Her goal is to identify potential therapeutic targets not only for this disease, but also for common diseases of impaired bone growth, including osteoporosis and delayed fracture healing. In addition, Xuhui Liu, MD shares his research in orthopedic surgery specifically on muscle biology. It has a critical role: poor muscle regeneration can limit recovery and increase the risk of re-injury.

Read the latest issue here: https://www.ncire.org/dna-newsletter

12/04/2025

When Missing Out Matters: Associations Between Social Activity Restriction and Caregiver Burden

Social engagement is crucial for well-being, yet caregivers often face restrictions due to care responsibilities. The caregiver-specific consequences of these restrictions are underexplored.

Drs. Kenneth Covinsky and Alexander K. Smith explore the social impact and burdens on caregivers in the study titled “When Missing Out Matters: Associations Between Social Activity Restriction and Caregiver Burden”, published in the Journal of the American Geriatrics Society.

Read it here: https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/jgs.70173

12/03/2025

National Influenza Vaccination Week, December 1st-5th, highlights the importance of continuing flu vaccinations through the holiday season and beyond. It’s not just the holiday season; it’s Flu Season. Flu activity usually increases in October but peaks between December and February. Flu activity sometimes occurs as late as May. NCIRE encourages everyone to take preventative measures for you and your loved ones this Flu Season.

Learn more: https://www.prevention.va.gov/flu/

Address

4150 Clement Street (151NC)
San Francisco, CA
94121

Opening Hours

Monday	8am - 4:30pm
Tuesday	8am - 4:30pm
Wednesday	8am - 4:30pm
Thursday	8am - 4:30pm
Friday	8am - 4:30pm

Telephone

+14157506954

Website

https://bsky.app/profile/ncire.org, https://www.linkedin.com/company/ncire/, https://www.ncire.org/

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Through new technologies, novel scientific insights, and international clinical collaborations, we strive to set a new standard of health care for veterans and military personnel.