
09/28/2025
A 40-year-old man with an 8-year history of hypertension and hyperlipidemia presented for examination. The visual acuity was 20/20 (both eyes) without visual field defects. Fundus photograph (A) demonstrated a bright yellow-white Hollenhorst plaque at the infero-temporal arteriole of the left eye. Adaptive optics imaging (B) identified the plaque as a dome-shaped lesion (360.4 μm × 123.4 μm) attached to the vessel wall. Swept-source OCT B-scan (C) displayed the plaque as a hyperreflective signal within the arteriolar lumen, while OCT angiography (D) confirmed narrowed but continued blood flow along the vessel.
From “High-resolution Multimodal Imaging of Nonocclusive Hollenhorst Plaque” by Qingge Guo, MD, Xiaohong Guo, MD, Bo Lei, MD, PhD. Published by Ophthalmology Retina online on July 17, 2025.
https://www.ophthalmologyretina.org/article/S2468-6530(25)00278-7/fulltext