Dr. Paul E. Hughes, Orthopedic Surgeon & Sports Medicine

Dr. Paul E. Hughes, Orthopedic Surgeon & Sports Medicine Hughes Orthopedics
Orthopaedic TOP DOC California Regenerative Medicine with Stem Cell therapies

We are dedicated to delivering stem cell treatments to patients, yielding consistently positive results. Would you like ...
07/21/2025

We are dedicated to delivering stem cell treatments to patients, yielding consistently positive results. Would you like to schedule a consultation? Use the code word "Hunter" for a complimentary consult.

03/26/2025

How many people have had a biologic therapy like PRP or BMAC?

03/19/2025

Hughes Orthopedics is a great destination for the patient looking for alternative treatments for joint pain. These in office procedures involved treating your joints at multiple sites with a one time procedure that can provide joint pain relief. This is using your own cells and your own plasma to do this. There is minimal downtime with awesome results as we have testimonials from many patients who have done well with this. Most orthopedic surgeons would not get a total joint replacement on themselves and would also look for these alternative treatments. How do I know this because I'm an orthopedic surgeon who would never get any joint replacement and neither would most of my orthopedic colleagues. We orthopedic surgeons know the complications that can happen with these procedures, which are frankly "nasty". I hope to provide more information for you and start a open dialogue about treatments that can be done here in the United States and without the need to go overseas.

03/09/2025

Hughes Orthopedics is a great destination for the patient looking for alternative treatments for joint pain. These in office procedures involved treating your joints at multiple sites with a one time procedure that can provide joint pain relief. This is using your own cells and your own plasma to do this. There is minimal downtime with awesome results as we have testimonials from many patients who have done well with this. Most orthopedic surgeons would not get a total joint replacement on themselves and would also look for these alternative treatments. How do I know this because I'm an orthopedic surgeon who would never get any joint replacement and neither would most of my orthopedic colleagues. We orthopedic surgeons know the complications that can happen with these procedures, which are frankly "nasty". I hope to provide more information for you and start a open dialogue about treatments that can be done here in the United States and without the need to go overseas.

Recent study shows PRP injections provide superior and clinically relevant improvements in pain and function over cortic...
02/18/2025

Recent study shows PRP injections provide superior and clinically relevant improvements in pain and function over corticosteroids at mid- and long-term follow-ups in knee OA patients, making them a more effective intra-articular option. Clinicians should consider PRP as a preferable treatment for sustained symptom relief.

01/12/2025

An ACL tear can be repaired. We have had many patients who are very happy with a repair not having a reconstruction which is an easier recovery and using BMAC enhancement @ 4-6 weeks post operative

01/10/2025

I recently aspirated my own bone marrow in my office and recorded it. If I can do this to myself, just think I'll easily. I can take your own bone marrow and use it to heal your joints.

I've been getting questions about other regenerative medicine clinics. Our advantage is that we're run by Orthopedic Sur...
12/15/2024

I've been getting questions about other regenerative medicine clinics. Our advantage is that we're run by Orthopedic Surgeon who has been providing treatments with regenerative techniques for over 10 years. He has injected over 15,000 patients over his 20 year career. Not to say the other clinics can't provide help but we provide the most technologically advanced treatment treatments that are best for you. Cellular regeneration from your bone marrow or your fat tissue is what is best. The literature shows us that.

11/30/2024

Stampede at Disneyland 8 AM running for space Mountain

A recent message from patient who had knee injections with bone marrow aspirate about a year agoHey Doctor Hughes!I'm do...
11/23/2024

A recent message from patient who had knee injections with bone marrow aspirate about a year ago

Hey Doctor Hughes!
I'm doing ok, from a pain perspective, to the extent i don't think i need or want any further shots at the moment.
Knees are doing great.

Your trusted orthopedic surgeon in San Mateo, CA. Expert care for optimal musculoskeletal health and mobility. Contact us today!

09/26/2024

I'm intrigued by the debate around Christian McCaffrey seeking treatment for his Achilles tendon in Germany. Some might argue he had other viable options like PRP, bone marrow aspirate concentrate, or umbilical cord stem cells. This choice may seem like a slight to his physicians at Stanford, including their world-renowned stem cell experts. Food for thought, especially for orthopedic surgeons.

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San Mateo, CA

Opening Hours

Monday 9am - 5pm
Tuesday 9am - 5pm
Wednesday 9am - 5pm
Thursday 9am - 5pm
Friday 9am - 5pm

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Paul Hughes, MD

At the leading edge of early diagnostics and advanced treatments, Paul Eliot Hughes, MD, offers comprehensive orthopedic care at his practice in San Mateo, California. Dr. Hughes specializes in minimally invasive surgeries to help patients enjoy a healthy, happy, pain-free life. Dr. Hughes is fellowship trained in sports medicine, learning from the country’s best at medical institutions around the country. Throughout his training, Dr. Hughes served as the team physician for the St. Louis Rams football team, the St. Louis Cardinals baseball team, and the St. Louis Blues hockey team. In addition to his clinical work, Dr. Hughes is involved in the research and development of medical devices and serves as an advisor to new media, several medical companies, and the College of San Mateo, a two-year community college in his city of practice. With a passion for helping others, he dedicates many hours working with the underserved and less fortunate members of the San Mateo community and surrounding area. Dr. Hughes has a reputation for going above and beyond for his patients, making special house calls to the elderly and children with special needs. Dr. Hughes has traveled as far as Australia and Hong Kong to perform cutting-edge surgeries. Dr. Hughes obtained his undergraduate degree in physics from UCLA, graduating summa cm laude and first in his class. He went on to attended the Keck School of Medicine at the University of Southern California. He was chief resident at George Washington University Medical School in Washington, D.C. during his residency and was recognized by the Washington, D.C. Orthopedic Society for creating the top research paper. At his San Mateo orthopedic practice, Dr. Hughes offers the latest in minimally invasive surgical techniques, including arthroscopies and computer-assisted surgical techniques. He is dedicated to assisting his patients through surgical and nonsurgical treatment to address chronic pain in the back, hips, and knees. He is highly experienced in innovative procedures, such as platelet-rich-plasma (PRP) injections and stem cell treatments.

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