02/18/2026
"Melasma is a significant ordeal for the patient and a true challenge for the aestheticians. These symmetrical brown patches on the face — which fade only to return with a vengeance after the very first sunny day — take a serious toll on a patient’s quality of life and self-esteem So, why is it so difficult to treat?
Under the microscope, melasma appears far more complex than a simple accumulation of pigment. In affected areas, scientists have discovered not only hyperactive melanocytes but also an abnormal number of blood vessels and mast cells. This suggests that melasma is the result of a 'faulty dialogue' between skin cells, blood vessels, and the local immune system. If we focus solely on stripping away pigment while ignoring the vascular and inflammatory components, lasting results will remain elusive.
Tranexamic acid not only combats excess pigmentation but also soothes the vascular network and normalizes local immunity. Thus, it targets the three key drivers of melasma:
-The Pigmentary
-The Vascular
-The Immune
Pro Brite plus serum from contains 4% Tranexamic acid