05/10/2023
When there is an injury or damage to a tissue, the body's immune system initiates an inflammatory response as a part of the healing process.
The inflammatory response is characterized by increased blood flow, increased permeability of blood vessels, and infiltration of immune cells, such as neutrophils and macrophages, to the site of injury.
The pro-inflammatory response plays an essential role in tissue repair as it helps to remove damaged cells, clear debris and initiate tissue regeneration (2).
Some of the benefits of pro-inflammatory response in tissue repair are:
1️⃣ It recruits immune cells to the site of injury, which helps to remove the damaged tissue and clear debris (3).
2️⃣ It stimulates the proliferation of fibroblasts, which are cells that produce the extracellular matrix that provides structural support for the tissue (4).
3️⃣ It initiates angiogenesis, which is the formation of new blood vessels, that helps to provide oxygen and nutrients to the injured tissue (5).
Here are two therapeutic techniques we use here at Stretch Clinic to create a pro-inflammatory response in tissue repair:
1️⃣ Gaston technique: The Gaston technique is a manual therapy technique that involves applying deep pressure to soft tissue via surgical steel instruments to create a pro-inflammatory response. This technique has been shown to be effective in treating various musculoskeletal conditions, such as chronic neck pain and plantar fasciitis.
2️⃣ Myofascial decompression: Myofascial decompression is a technique that involves the application of negative pressure to soft tissue to create a pro-inflammatory response. This technique has been shown to be effective in treating various musculoskeletal conditions, such as low back pain and Achilles tendinopathy.
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References:
1. Nathan, C. (2002). Points of control in inflammation. Nature, 420(6917), 846-852.
2. Koh, T. J. (2018). DiPietro LA. Inflammation and wound healing: the role of the macrophage. Expert Reviews in Molecular Medicine, 13:e23.
3. Martin, P., & Leibovich, S. J. (2005). Inflammatory cells during wound repair: the good, the bad and the ugly. Trends in Cell Biology, 15(11), 599-607.
4. Badylak, S. F., & Gilbert, T. W. (2008). Immune response to biologic scaffold materials. Seminars in Immunology, 20(2), 109-116.
5. Folkman, J. (1995). Angiogenesis in cancer, vascular