04/17/2026
Immunotherapy is changing cancer care — but there’s still more work to do.
Immunotherapy has joined surgery, radiation and chemotherapy as a major pillar of cancer treatment. For some patients, it can even provide lifelong protection against a cancer returning.
These treatments work by helping the immune system “see” cancer cells again — using tools like CAR T cells, immune checkpoint inhibitors and antibody-based therapies. In certain cancers, including melanoma, they’ve led to powerful, life-changing responses.
But here’s the reality: most patients don’t benefit yet.
Even in cancers considered “responsive,” only about 30% of patients see lasting results. For people with pancreatic, uterine, germ cell and many other cancers, immunotherapy often hasn’t made a difference at all.
“Our immune system is designed to protect us from cancer,” says Dr. Kevin Barry, a molecular biologist at Fred Hutch. "But the immune system can be overrun by cancer. Only around 30% of patients respond to this type of treatment ... we have work to do.”
Thanks to a $270,000 grant from the American Cancer Society, Dr. Barry is taking on that challenge. His team will study how the tumor’s immediate environment helps cancer hide from the immune system — and how we might break that protection to help more patients respond to treatment.
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