Kaiser Permanente Washington Health Research Institute

Kaiser Permanente Washington Health Research Institute Kaiser Permanente Washington Health Research Institute does research that helps people stay healthy.

Kaiser Permanente Washington Health Research Institute (KPWHRI), formerly Group Health Research Institute, does practical research to improve the health and health care of Kaiser Permanente members and the public. Kaiser Permanente is recognized as one of America’s leading health care providers and not-for-profit health plans. We include:
* The MacColl Center for Health Care Innovation, which seek

s to transform care for people with chronic illnesses
* The Center for Community Health and Evaluation, which designs and evaluates health-related programs and initiatives throughout the United States

We are national leaders in scientific collaboration. The Institute is a founding member of the 18-site Health Care Systems Research Network--giving scientists access to vast data resources, population diversity, and statistical power

A new study provides more evidence that minimizing medications is important for healthy aging. Using data from the Adu...
07/16/2025

A new study provides more evidence that minimizing medications is important for healthy aging. Using data from the Adult Changes in Thought (ACT) Study, the researchers found that greater cumulative use of these medications was linked to significant declines in physical performance. JAMA Network Open https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2836242

A study led by Gregory Simon, MD, MPH, found that the risk of self-harm was not lower after people started taking bupren...
07/02/2025

A study led by Gregory Simon, MD, MPH, found that the risk of self-harm was not lower after people started taking buprenorphine for opioid use disorder. This likely reflects frequent discontinuation and the high risk of self-harm or overdose after ending treatment, underscoring the need to improve treatment continuity. https://www.clinicalkey.com/ #!/content/journal/1-s2.0-S0163834325001355

A new study led by KPWRHI researcher Laura Harrington, PhD, MPH, provides some of the best evidence to date linking sitt...
06/05/2025

A new study led by KPWRHI researcher Laura Harrington, PhD, MPH, provides some of the best evidence to date linking sitting for longer periods to the risk of potentially dangerous blood clots ( ) in older women.

Taking more breaks from sitting could potentially lower the risk.

A new paper from the Adult Changes in Thought (ACT) Study was featured on the cover of the current issue of the Internat...
05/20/2025

A new paper from the Adult Changes in Thought (ACT) Study was featured on the cover of the current issue of the International Journal of Environmental Research and Public Health. The researchers leveraged the ACT Study’s rich historic data on participants’ physical function over time to explore links between trajectories of functional health and physical activity, sitting time, and sleep patterns in later life. The results emphasized that the relationship between physical function and these behaviors is bidirectional — that is, better function may improve activity and vice versa. This was especially true for more intense physical activity. These findings support the call for interventions to promote physical activity earlier in life to preserve both physical function and the ability to engage in physical activity as people age. https://www.mdpi.com/1660-4601/22/5

Are your medications increasing your dementia risk? speaker Shelly Gray with University of Washington School of Pharma...
05/14/2025

Are your medications increasing your dementia risk? speaker Shelly Gray with University of Washington School of Pharmacy explored the pharmacoepidemiology and stem cell model evidence linking certain medications with dementia risk.

Day 2 of the virtual Adult Changes in Thought (ACT) Research Symposium is underway! Katherine Prater with University of ...
05/14/2025

Day 2 of the virtual Adult Changes in Thought (ACT) Research Symposium is underway! Katherine Prater with University of Washington kicked off this morning’s sessions with research showing that individuals who are resilient to Alzheimer’s disease have alterations in the morphology of their microglia (brain immune cells) and gene expression.

The long-running ACT Study provides extensive data to explore factors that may influence dementia risk. KPWHRI researche...
05/13/2025

The long-running ACT Study provides extensive data to explore factors that may influence dementia risk. KPWHRI researchers Dori Rosenberg and Mikael Anne Greenwood-Hickman joined UW collaborator Susan McCurry in sharing findings from their research looking at trajectories of cognitive and physical function over 10 years in relation to physical activity, sedentary time, and sleep.

speaker Steve Nguyen with UC San Diego Herbert Wertheim School of Public Health and Human Longevity Science shared res...
05/13/2025

speaker Steve Nguyen with UC San Diego Herbert Wertheim School of Public Health and Human Longevity Science shared research linking moderate-to-vigorous physical activity with a lower risk of .

Keynote speaker Dr. Rebecca Gottesman with the National Institute of Neurologic Disorders and Stroke kicked off with a...
05/13/2025

Keynote speaker Dr. Rebecca Gottesman with the National Institute of Neurologic Disorders and Stroke kicked off with a talk about research into modifying risk over the course of a person’s life.

It’s the first day of the virtual Adult Changes in Thought (ACT) Research Symposium! This year's theme is: "Vascular con...
05/13/2025

It’s the first day of the virtual Adult Changes in Thought (ACT) Research Symposium! This year's theme is: "Vascular contributions to cognitive impairment and dementia with a focus on s*x differences." Interested in attending? There's still time to register for this online event: Z2Bir7trg1blWkx9@9cG/" rel="ugc" target="_blank">https://whova.com/portal/registration/Z2Bir7trg1blWkx9@9cG/

2025-05-13, Virtual

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Seattle, WA

Opening Hours

Monday 8am - 5pm
Tuesday 8am - 5pm
Wednesday 8am - 5pm
Thursday 8am - 5pm
Friday 8am - 5pm

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(206) 287-2900

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Kaiser Permanente Washington Health Research Institute conducts practical research that helps people around the world stay healthy. Kaiser Permanente is recognized as one of America’s leading health care providers and not-for-profit health plans. We include: * The MacColl Center for Health Care Innovation, which seeks to transform care for people with chronic illnesses * The Center for Community Health and Evaluation, which designs and evaluates health-related programs and initiatives throughout the United States We are national leaders in scientific collaboration. The Institute is a founding member of the 20-site Health Care Systems Research Network--giving scientists access to vast data resources, population diversity, and statistical power.