12/15/2025
Why I only take a small amount of niacin.
1-MNA, or 1-methylnicotinamide, is a compound naturally produced in our bodies, mainly in the liver, as a byproduct of niacin metabolism. While it's present in vitamin B3-rich foods, these dietary sources add only a small amount of 1-MNA to our
bodies.
1-MNA operates at the cellular level to help balance key molecular pathways involved in NAD regulation, energy production, vascular function, oxidative stress management, and longevity.
1-MNA safely boosts NAD levels in cells while avoiding issues with NNMT, an enzyme linked to diseases like cancer,
obesity, heart disease, and dementia. 1-MNA helps balance NAD and NNMT to optimize NAD levels.
1-MNA is crucial for energy within cells and helps cells use their energy stores more efficiently.
By controlling the NNMT enzyme, 1-MNA lowers certain inflammatory proteins and cytokines, which are tied to age-related diseases
1-MNA promotes cardiovascular health by managing oxidative stress.
1-MNA increases the stability of sirtuins, proteins that help regulate the body's cellular health and aging process.
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