09/24/2025
The recent announcement by HHS regarding acetaminophen (Tylenol) use is not backed by the full body of scientific evidence. The American College of Obstetrics and Gynecology (ACOG) and the Society of Maternal-Fetal Medicine (SMFM) agree that pregnant patients can continue to rely on acetaminophen for managing pain and fever.
As many who are familiar with autism know, autism is primarily genetically established before birth through complex factors beyond anyone’s control. A nationwide Swedish cohort study of nearly 2.5 million children, born between 1995 and 2019, found no significant association between acetaminophen use during pregnancy and increased risk of autism, ADHD, or intellectual disability after accounting for familial and medical confounders. The authors concluded that the previously reported associations between acetaminophen use in pregnancy and neurodevelopmental disorders are likely attributable to familial or genetic confounding rather than a causal effect of the drug.
The risks of untreated fever during pregnancy are well-established. Fevers above 100.4F in the first trimester are proven to increase risk of miscarriage, neural tube defects, congenital heart issues, stillbirth, and preterm delivery. Other options like ibuprofen are not recommended in pregnancy as they can cause serious complications in your baby.
Whenever taking any medication, the goal is to use the lowest effective dose for the shortest time needed. If you need to use acetaminophen for more than a few days or you have any concerns, please contact your provider.
For additional guidance and evidence-based resources on this topic, we encourage you to explore the following trusted organizations:
American College of Obstetricians and Gynecologists Statement: https://ow.ly/kr6250X1ahL
Society for Maternal-Fetal Medicine Statement: https://ow.ly/HSHv50X1ahN
