02/07/2026
Micro-dosing GLP-1 medications: trend, tool, or trouble?
As a board-certified obesity physician, I’ve been getting this question almost daily.
“Can I just take a tiny dose of GLP-1 long-term?”
Here’s the truth most people aren’t hearing:
GLP-1 medications like semaglutide and tirzepatide are not magic because of the dose - they work because of how they change the brain-body signaling around hunger, satiety, and metabolic regulation.
Micro-dosing may help some patients with:
• Reducing “food noise”
• Improving portion control
• Enhancing metabolic stability
• Maintaining weight loss after reaching goal
But micro-dosing is NOT appropriate for everyone.
Too low of a dose may:
• Fail to adequately treat the biology of obesity
• Lead to weight regain
• Create frustration and discouragement
• Give the false impression that the medication “doesn’t work”
Obesity is a chronic, relapsing, biologically driven disease — not a willpower problem.
The goal is not the lowest dose possible.
The goal is the right dose for your biology.
For some patients, that may be a lower maintenance dose. For others, it requires a higher therapeutic dose to fully quiet the disease process.
This is why medical supervision matters.
Not social media protocols.
Not compounded guesswork.
Not DIY dosing.
Personalized, evidence-based obesity care.
If you’ve been curious about GLP-1 therapy, micro-dosing, or long-term maintenance, the most important step is working with a physician trained in obesity medicine who understands the chronic nature of this disease.
Because treating obesity isn’t about chasing trends.
It’s about restoring metabolic health for the long term.
Priyanka MD, DipABOM
Allwell Clinic
Televisits all over Texas
All insurance and Wmdicare accepted