Fispghan

Fispghan Federation of the International Societies for Pediatric Gastroenterology, Hepatology and Nutrition (FISPGHAN)

Autoantibody signatures in children with celiac disease, juvenile idiopathic arthritis, and polyautoimmunityNan Du, Deni...
12/16/2025

Autoantibody signatures in children with celiac disease, juvenile idiopathic arthritis, and polyautoimmunity
Nan Du, Denis Chang, Madison Wong, Jay R. Thiagarajah, Erin Janssen, Lauren A. Henderson, Krishnan Raghunathan, Jocelyn A. Silvester
https://doi.org/10.1002/jpr3.70119
Use of multiplex antigen arrays in patients with and without polyautoimmunity is a valuable tool to identify known and potentially novel disease-antigens. Further study is needed to determine the role of H/K ATPase autoantibodies in monitoring of CeD patients.

This month in JPGN Reports: When manual disimpaction isn't enough: Case report and review of neostigmine's role in refra...
12/15/2025

This month in JPGN Reports: When manual disimpaction isn't enough: Case report and review of neostigmine's role in refractory constipation management
Mojdeh Mostafavi, Sarah Lee, Victoria Martin
https://doi.org/10.1002/jpr3.70115
Severe refractory constipation can lead to f***l retention requiring hospitalization, nasogastric cleanout, or manual disimpaction, and in some cases, surgery. Neostigmine, a reversible acetylcholinesterase inhibitor, is commonly used for pseudo-obstruction but rarely for refractory constipation. Here, we report a 21-year-old male with chronic constipation and likely undiagnosed autism spectrum disorder hospitalized for severe f***l retention, unresponsive to nasogastric polyethylene glycol. Manual disimpaction removed distal stool but left significant proximal stool burden. A carefully monitored trial of intravenous neostigmine, 4 mg in divided doses, resulted in substantial stool passage without bradycardia or other adverse effects. This case highlights neostigmine as a safe and effective adjunct to manual disimpaction. Its use may improve outcomes and reduce the need for surgical intervention in select patients with complex gastrointestinal motility disorders.

This month in JPGN Reports: Helicobacter pylori prevalence and its association with f***l occult blood and hemoglobin c...
12/15/2025

This month in JPGN Reports: Helicobacter pylori prevalence and its association with f***l occult blood and hemoglobin concentration in children in Ilam, Iran
Saeed Hemati, Zahra Mahdavi, Zeinab Mohsenipour
https://doi.org/10.1002/jpr3.70069
Helicobacter pylori (H. pylori) is a widespread Gram-negative bacterium, affecting over half of the global population. This study investigated the prevalence of H. pylori among children in Ilam, western Iran, and assessed potential associations between infection, f***l occult blood tests (FOBT), hemoglobin concentration (HbC), and seasonality.

This month in JPGN Reports: Maralixibat for the treatment of severe xanthomas in two children with Alagille syndrome: Ca...
12/12/2025

This month in JPGN Reports: Maralixibat for the treatment of severe xanthomas in two children with Alagille syndrome: Case reports
Geetanjali Bora, Ruben E. Quiros-Tejeira, Bernadette Vitola
https://doi.org/10.1002/jpr3.70105

This month in JPGN Reports: Improving patient satisfaction in a multidisciplinary pediatric feeding clinicSussette Gonz...
12/12/2025

This month in JPGN Reports: Improving patient satisfaction in a multidisciplinary pediatric feeding clinic
Sussette Gonzalez Szachowicz, Linda Cooper-Brown, Scott Dailey, Emily Garcia, Liyun Zhang, Amy Pan, Rose Lee
https://doi.org/10.1002/jpr3.70067

Pediatric feeding disorders can result from psychosocial dysfunction, poor feeding skills, or medical or nutritional disorders. The primary aim of this study was to evaluate patient satisfaction at the multidisciplinary feeding clinic (MFC) and improve patient satisfaction by reducing patient wait times, improving communication, maximizing clinic space, and expanding inclusivity of our patients and their families in the decision-making process.

MORE TIME TO SUBMIT YOUR RESEARCH We’d like to thank everyone who has already submitted their abstracts. Your contributi...
12/12/2025

MORE TIME TO SUBMIT YOUR RESEARCH

We’d like to thank everyone who has already submitted their abstracts. Your contributions are helping to shape the future of paediatric gastroenterology, hepatology, and nutrition. Your work advances clinical practice, strengthens evidence-based care, and supports collaboration across the international community.

If you missed the deadline, to support you in presenting your best work, we’ve extended the abstract submission deadline to 5 January 2026. This is your opportunity to share your latest research, clinical insights, and evolving perspectives with peers and global experts at ESPGHAN 2026.

Use this additional time to refine your abstract and make sure your voice is heard at the leading global platform in paediatric gastroenterology, hepatology, and nutrition.

Extended Abstract Submission Deadline: 5 January 2026
https://espghancongress.org/

Impact of elexacaftor/tezacaftor/ivacaftor on biomarkers of cystic fibrosis hepatobiliary involvement in the PUSH studyW...
12/11/2025

Impact of elexacaftor/tezacaftor/ivacaftor on biomarkers of cystic fibrosis hepatobiliary involvement in the PUSH study
Wen Ye, et al
https://doi.org/10.1002/jpn3.70290

This month in JPGN Reports: Over-the-wire insertion of a naso-duodenal feeding tube in a critically ill infantHashim Ab...
12/11/2025

This month in JPGN Reports: Over-the-wire insertion of a naso-duodenal feeding tube in a critically ill infant
Hashim Abdul-Khaliq, Jochen Pfeifer
https://doi.org/10.1002/jpr3.70122
In a 7-month-old boy (body weight 7 kg) with congenital heart disease, short bowel syndrome, and gastric motility disorder, conventional insertion of a duodenal feeding tube was unsuccessful (Figure 1).

This month in JPGN Reports: Peripheral blood cytokine levels in paediatric-onset inflammatory bowel disease: A systemati...
12/10/2025

This month in JPGN Reports: Peripheral blood cytokine levels in paediatric-onset inflammatory bowel disease: A systematic review and meta-analysis
Sabine Jansson, Andrea Ehrström, Charlotte Ulrikka Rask, Johan Burisch, Michael Eriksen Benros, Jakob Seidelin, Mikkel Malham, Vibeke Wewer
https://doi.org/10.1002/jpr3.70116

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