Doctor Steven Murphy

04/14/2026

https://open.substack.com/pub/doctormurphy/p/osteoarthritis-is-a-mitochondrial?r=599bm2&utm_medium=ios I teach you my playbook to avoid a knee replacement!

The Science to Prevent Knee Replacement Surgery!

04/14/2026

Breathtaking. We only use autologous cells in our clinics in the US.

03/09/2026

Today I address one of the hottest topics trending Facebook.

A patient asked me a question recently that I did not expect.

“Doctor… do GLP-1 drugs make people less interested in everything?”

At first I laughed. It sounded like internet nonsense.

But then I started seeing the same comments everywhere.

People taking medications like Ozempic, Wegovy, and Mounjaro often report:

• Food cravings disappear
• Alcohol becomes less appealing
• Impulsive spending drops
• Some even notice a change in libido

That raises a fascinating scientific question.

These drugs clearly quiet hunger signals.

But they also act on the brain’s reward system.

So the real question becomes:

If we turn down the brain’s craving circuits… what else might get quieter?

To be clear, there is no evidence GLP-1 drugs prevent love or relationships. The metabolic benefits of these medications are profound and life-changing for many patients.

But the conversation reveals something important about modern longevity medicine.

We are getting very good at helping people live longer.

We are still learning how to make sure we don’t flatten the experience of living in the process.

I wrote a deep dive exploring the science, the internet debate, and what we actually know so far.

Read the full article here:

https://open.substack.com/pub/doctormurphy/p/ozempic-love-and-the-longevity-trade?r=599bm2&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true

Here’s to a life well lived, not just a longer one.

— Dr. Murphy

09/01/2025

Did you know IV NAD has been around since the 1950s?
Addiction clinics used it with great success and no fatalities. Yet today, top geroscientists call it risky, inefficient, or even dangerous.

In my latest piece, I share Iain De Havilland’s rebuttal to Eric Verdin’s “never do IV NAD” comment—alongside my own analysis.

👉 Read the exchange: 🔗 https://open.substack.com/pub/doctormurphy/p/the-great-nad-debate-infusions-under?r=599bm2&utm_medium=ios🔗

This is what real longevity dialogue looks like.

08/19/2025

Here’s something most people don’t know: Alzheimer’s begins 20–30 years before the first symptom.

It’s a silent process, driven by inflammation, metabolic dysfunction, mitochondrial decline, and environmental mismatch. By the time memory starts to slip, much of the brain damage has already occurred.

I’ve spent years in longevity and brain health medicine, and I’ve seen a pattern: Prevention isn’t just possible — it’s powerful — but only if you act early and layer your approach.

That’s what I’ll be sharing today on My Substack:

The foundational lifestyle steps (from the Bredesen Framework) that align metabolism, sleep, stress, and brain engagement

How low-dose lithium and rapamycin can protect neurons and clear toxic proteins

The supplements I actually recommend, and why form and dose matter

Cutting-edge neurotechnologies you’ve probably never heard of

How your light environment — from morning sun to nighttime blue light — shapes brain aging at the quantum level

https://open.substack.com/pub/doctormurphy/p/the-alzheimers-prevention-playbook?r=599bm2&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true

If you have a parent with Alzheimer’s, carry APOE4, or just want to protect your brain as you age — this will be worth your time.

08/14/2025

A trace mineral in your water may protect your brain.
A new Nature study shows that low lithium levels can accelerate Alzheimer’s-like changes—plaques, tangles, inflammation, memory loss. Restoring lithium reversed the damage, calming brain inflammation and supporting regeneration.

In my latest Longevity Insider post, I connect these findings to the bioelectric blueprint of regeneration and even the microtubule-level theories of consciousness. The result? A vision of brain health that works at molecular, electrical, and possibly quantum scales.

Read the full breakdown here: https://open.substack.com/pub/doctormurphy/p/deep-dive-lithium-neurogenesis-microglia?r=599bm2&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true

05/29/2025

https://open.substack.com/pub/doctormurphy/p/the-most-powerful-medicine-youve?r=599bm2&utm_medium=ios This post is for those who want to maximize gains from peptide therapy, safely.

From BPC-157 to Tirzepatide: What Doctors AND Patients Must Know Now

05/23/2025

1 hr before bed, take a shower. Sleep better. You’re welcome!

05/23/2025

Interested in Anti-aging and Longevity? This post on peptides is a great primer!

From BPC-157 to Tirzepatide: What Doctors AND Patients Must Know Now

04/14/2025

Absolutely Agreed. We will continue to write for
203-822-5450 www.conciergemedical.ai

04/12/2025