07/21/2025
♡Bryan Family Introductions♡
Together, our growing community is turning hope into action. Your support lights the way forward, and we’re honored and forever grateful to have you with us on this journey.
đź’™Who Are We?
We are The Bryans- Beau, JeanAnn, Sawyer (13) & Wesley (10) and we have called Tea, SD our home for the last 17 years. In 2019 both of our boys were diagnosed with Duchenne Muscular Dystrophy (DMD), a fatal muscle-wasting disease.
đź’”What is Duchenne Muscular Dystrophy (DMD)?
DMD is the most common, fatal genetic disorder diagnosed in childhood affecting 1 in every 3,500 male births and is 100% fatal. Boys with DMD lose muscle throughout their life, typically lose the ability to walk around age 10, and do not survive their mid-twenties. Rate of progression varies for each individual.
🚫Is There A Cure?
With over 3,000 possible separate mutations in the dystrophin gene there is no cure-all. Our boys have an ultra-rare duplication within their gene, interrupting their body’s ability to produce the protein needed to maintain and support healthy muscle. The best hope for our boys is to receive a treatment via a therapy specifically designed for their mutation.
🧬Who Is Cure Rare Disease (CRD)?
CRD is a non-profit biotech company based out of Woodbridge, CT that is making history by accelerating the pathway to life-saving gene therapies for people with rare neuromuscular diseases, who need them now. CRD and its collaborators are harnessing CRISPR technology to edit and correct mutated DNA to restore proper function to the dystrophin gene.
đź§ŞCRD and the Bryan Boys
Since 2020, CRD has been developing a treatment specifically for Sawyer and Wesley. A team of scientists have created a therapeutic for their mutation that is proving to be successful in the lab, and manufacturing is just around the corner! They’ll be among the first in the world to receive this breakthrough therapy, helping pave the way for countless others battling rare diseases who have no other options.
🙏How You Can Help
Producing and delivering this life-saving therapy costs around $2.2 million. Your support is crucial to continue this life-saving work. Together, we can give Sawyer, Wesley, and countless others a chance at a long, happy and healthy life.
🔥Bryan Boys Igniting Hope Campaign
From the Zippy Mile on May 17 to the Bryan Boys 5K on September 27, 2025 we're launching a nationwide challenge to raise $800,000 to begin manufacturing Sawyer & Wesley’s custom treatment for Duchenne Muscular Dystrophy- a devastating and fatal muscle-wasting disease.
🔎To Donate or Learn More
www.bryanboys.org