03/26/2026
FYI
Psychiatry
Use of Psychotropic Drugs Linked to Bone Loss in Men
March 20, 2026
A cohort study of 940 men aged 20 years and older found that psychotropic medications, especially selective serotonin reuptake inhibitors (SSRIs) and anticonvulsants, are linked to bone loss at the spine and hip, particularly in men with lower BMI. The study, conducted over a median of 13.2 years, adjusted for various confounders such as socioeconomic status and lifestyle factors, confirmed these associations. Anticonvulsants showed a significant impact on hip bone mineral density (BMD), while SSRIs and antidepressants affected spine BMD. These findings emphasize the need for careful management of bone health in patients using these psychiatric medications.
The Takeaway: Psychotropic drugs, especially SSRIs and anticonvulsants, are linked to bone loss in men, particularly those with low BMI, underscoring the need for personalized bone health monitoring.
Quoted from Medscape