Elite Megastore

11/04/2025

So far, six people have died nationwide, and 27 illnesses have been reported in connection with the listeria outbreak.

10/11/2025

@ :-)

10/05/2025

09/30/2025

4 dead, 19 hospitalized as a result of outbreak because of frozen meals. Link to story in comments

09/28/2025

08/21/2025

A first-of-its-kind cancer vaccine cleared tumors and prevented recurrence in some of the most lethal cancers.

A new cancer vaccine, ELI-002 2P, has shown encouraging results in a clinical trial targeting two of the deadliest cancers: pancreatic and colorectal.

Developed to home in on KRAS gene mutations — which are involved in 93% of pancreatic and 50% of colorectal cancers — the "off-the-shelf" vaccine triggered strong immune responses in most patients.

In a trial involving 25 individuals recovering from surgery, 84% developed KRAS-specific T cells, with nearly a quarter showing complete tumor clearance. Among those with the strongest immune responses, the majority remained cancer-free nearly 20 months later, far exceeding expected survival outcomes.

Unlike personalized cancer vaccines, ELI-002 2P does not require customization for each patient, making it more accessible and cost-effective. It uses a targeted delivery system to stimulate immune cells in the lymph nodes, aiming to prevent cancer recurrence after initial treatment. Researchers also found potential for broader effectiveness, noting the vaccine may help the immune system fight other cancer-related mutations. While further trials are needed, the results point to a powerful new tool in the fight against notoriously treatment-resistant cancers like pancreatic and colorectal.

paper
Wainberg, Z.A., Weekes, C.D., Furqan, M. et al. Lymph node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer: phase 1 AMPLIFY-201 trial final results. Nat Med (2025).

08/20/2025

🧠 The brain has a natural defense against Alzheimer’s, and scientists just found the switch to activate it!

Scientists just discovered the brain receptor that helps prevent Alzheimer’s by clearing toxic plaque.

In a study, researchers at UC San Francisco found that a specific brain receptor, ADGRG1, enables immune cells called microglia to act as high-efficiency cleanup crews. These cells remove toxic amyloid beta plaques — the sticky buildup that damages neurons and is closely tied to Alzheimer’s disease.

In both mice and human brain samples, high levels of ADGRG1 in microglia correlated with better plaque clearance, less brain degeneration, and stronger memory.

In contrast, low ADGRG1 levels meant more plaque, faster cognitive decline, and greater tissue damage.

Notably, the receptor belongs to a class of proteins already targeted by existing drugs, giving researchers hope for fast-tracked therapies.

By boosting ADGRG1 activity, scientists believe we could “supercharge” microglia across the population — turning average brains into Alzheimer’s-resistant ones and potentially delaying or even preventing the disease for millions.

read the paper:
G-protein-coupled receptor ADGRG1 drives a protective microglial state in Alzheimer’s disease through MYC activation” – Beika Zhu et al., Neuron, July 25, 2025

08/18/2025

Fermentation boosts stevia’s ability to target cancer cells while leaving healthy ones unharmed.

08/11/2025

Eating 3 weekly servings of French fries linked to higher diabetes risk:

Eating three servings of French fries a week is associated with a 20% increased risk of developing type 2 diabetes, but eating similar amounts of potatoes cooked in other ways – boiled, baked or mashed – does not substantially increase the risk.

A large US study followed more than 205,000 health professionals for up to 40 years, tracking diet and health outcomes. Researchers found that for every three weekly servings of total potatoes, diabetes risk rose by 5%, but French fries stood out with a 20% increase. In contrast, plain potatoes prepared by boiling, baking, or mashing were not linked to a significant rise in risk.

Swapping potatoes for whole grains lowered diabetes risk, especially if replacing French fries, while replacing potatoes with white rice increased the risk. Potatoes are rich in nutrients like vitamin C and fibre, but their high starch content means they raise blood sugar quickly, so preparation method matters.

The study was observational, meaning it cannot prove cause and effect, and most participants were white health professionals, so results may not apply to everyone. Researchers say whole grains should still be a priority, but plain potatoes can be part of a healthy diet, especially when not fried.

Source: Mousavi, Seyed Mohammad, et al. "Total and specific potato intake and risk of type 2 diabetes: results from three US cohort studies and a substitution meta-analysis of prospective cohorts." bmj 390 (2025).

08/10/2025

Scientists just used lithium supplements to reverse Alzheimer's-like memory loss!

Harvard Medical School researchers have uncovered a potentially game-changing link between lithium and Alzheimer’s disease.

By analyzing hundreds of human brain and blood samples from healthy individuals, those with mild cognitive impairment, and people with advanced Alzheimer’s, the team found that lithium levels were significantly lower even in the earliest stages of memory loss.

They also discovered that amyloid-beta plaques — a hallmark of Alzheimer’s — appear to bind to lithium, reducing its availability to neurons and accelerating disease progression.

This marks the first time lithium, already used in psychiatric medicine, has been shown to occur naturally in the brain at biologically meaningful levels.

In mouse models, lithium depletion caused rapid buildup of amyloid-beta and tau proteins, inflammation, and cognitive decline. The breakthrough came when researchers tested lithium orotate, a form of lithium that evades amyloid-beta binding. At extremely low doses, it reversed memory loss and other Alzheimer’s-like symptoms in mice without signs of toxicity. While human trials are still needed, the findings suggest lithium testing could one day help identify those at risk, and targeted lithium supplementation might become a preventive or restorative therapy for dementia.

Source: Yankner, B., Aron, L., et al. (2025). Lithium depletion drives Alzheimer’s disease and brain aging. Nature.

08/09/2025

Having less s*x may make you 70% more likely to die early, study shows.

Women who have s*x less than once a week may face a significantly higher risk of dying early, according to research analyzing health data from over 14,500 Americans.

The study found that women with less frequent s*xual activity were 70% more likely to die during the 10-year follow-up period compared to those who had s*x more often.

While the link wasn’t found in men, the data did show that people suffering from depression who also had low s*xual frequency were about three times more likely to die during the same period—suggesting s*x may help counter some of the deadly effects of mental health issues.

Researchers emphasized that while they can’t prove s*x directly causes better health, the findings align with previous research showing s*x can boost mood, improve cardiovascular health, and enhance overall well-being.

Importantly, the health benefit appeared to grow with more frequent s*x, especially for women. This study adds to mounting evidence that an active s*x life may be more than just pleasurable—it could be a vital part of living longer and healthier.

source
Banerjee S, Anderson P, Davis WS. Connection Between Depression, Sexual Frequency, and All-cause Mortality: Findings from a Nationally Representative Study. Journal of Psychos*xual Health. 2024;6(1):35-44

07/22/2025

A world-first lung cancer vaccine has officially entered human trials.

In a historic step toward revolutionizing cancer treatment, doctors have launched the world’s first clinical trial of an mRNA vaccine for lung cancer.

Developed by BioNTech—the same company behind one of the COVID-19 vaccines—this new jab, called BNT116, targets non-small cell lung cancer (NSCLC), the most common and deadliest form of the disease.

The vaccine is designed to train the immune system to recognize and destroy cancer cells and prevent their return, offering hope for thousands facing the often grim prognosis of advanced lung cancer.

The phase 1 trial is being conducted at 34 sites across seven countries, including the UK, US, and Germany.