22/07/2025
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A groundbreaking study from the University of Iowa and Leiden University Medical Center found that a 100:1 ratio of CBD to THC was the most effective at reducing migraine-like symptoms in mice. While CBD or THC alone showed limited results, this specific combination eased light sensitivity, pain, and other migraine markers across three validated models.
This is big news for the millions who use cannabis to manage migraines—especially since most clinical guidance still lacks clarity on dosing and cannabinoid ratios. The findings help set a scientific foundation for future human trials and offer a potential path toward safer, non-opioid migraine therapies.
As access to medical cannabis grows, so should our understanding of how it works. This research moves us one step closer to using cannabis more intentionally, effectively, and holistically in migraine care.