Joseph Tartaglia MD

Joseph Tartaglia MD Announcing a new non invasive strategy for the treatment of coronary artery ischemic heart disease.

08/01/2025

Researchers just found two meds that reversed Alzheimer’s brain changes in mice.

Both drugs are already FDA-approved, potentially speeding their path toward human clinical trials.

Letrozole, typically used for breast cancer, and irinotecan, commonly prescribed for colon and lung cancer, were found to significantly reduce toxic tau protein build-up and improve memory and learning in Alzheimer’s mouse models.

The discovery, led by researchers at UCSF and Gladstone Institutes, began with a computational analysis of gene expression changes in Alzheimer’s patients.

By matching those patterns with existing drug profiles in the Connectivity Map database and analyzing cancer patient records, researchers spotted an unexpected protective effect. Letrozole targeted damaged neurons, while irinotecan acted on glial cells—together offering a multi-pronged strategy against the disease. While side effects and further testing remain key hurdles, this innovative, data-driven approach could lead to faster, personalized Alzheimer’s treatments, offering hope to the 55 million people affected worldwide.

source
L. Yaqiao et al. Cell. July 2025. "Cell-type-directed network-correcting combination therapy for Alzheimer’s disease"

It’s easy to do and only takes 20 minutes a day.
07/10/2025

It’s easy to do and only takes 20 minutes a day.

SAN FRANCISCO — Women health care providers assigned to transcendental meditation vs. usual treatment had better burnout and anxiety scores at 3 months, according to data presented at the American Thoracic Society International Conference.The practice of transcendental meditation (TM) involves...

05/13/2025

A Narcissist Sells You a Dream—Then Turns It Into a Nightmare.

Charming, deceitful, and dangerously manipulative—Mark Wilson knows how to lure people in and tear them apart. Behind the Mask: The Rise of a Narcissist takes you deep inside the mind of a master manipulator, from his early lies to his web of toxic relationships.

If you’ve ever been trapped in a narcissist’s cycle, this gripping novel will feel all too real. Survivors will relate. Others will be warned.

Dare to look behind the mask? Get your copy today: https://a.co/d/czX7KT2

05/13/2025
Omg ‼️
05/13/2025

Omg ‼️

As of May 2025, several viruses originating from China have been identified in the United States. While none currently p...
05/13/2025

As of May 2025, several viruses originating from China have been identified in the United States. While none currently pose a significant public health threat, health authorities continue to monitor them closely. Here's an overview:

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# # # 1. **Human Metapneumovirus (HMPV)**

* **Overview**: HMPV is a respiratory virus causing symptoms similar to the common cold or flu, such as cough, fever, congestion, and sore throat. ([New York Post][1])

* **Current Status**: Recent surges in HMPV cases have been reported in both China and the United States. In the U.S., cases have been increasing since November, with the CDC noting a rise in HMPV infections. ([New York Post][1])

* **Impact**: While most infections are mild, HMPV can lead to severe illness in young children, older adults, and immunocompromised individuals. There is currently no vaccine or specific treatment for HMPV; management focuses on supportive care. ([New York Post][1])

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# # # 2. **Langya Henipavirus (LayV)**

* **Overview**: Langya henipavirus is a newly identified virus first detected in eastern China between 2018 and 2021, with 35 reported human cases. ([PMC][2])

* **Symptoms**: Infected individuals exhibited symptoms such as fever, fatigue, and cough. No fatalities have been reported, and there is no evidence of human-to-human transmission. ([CDC][3])

* **U.S. Status**: As of now, there have been no reported cases of Langya henipavirus in the United States. However, a related henipavirus, the Camp Hill virus, was recently identified in shrews in Alabama, marking the first henipavirus discovery in North America. ([News-Medical][4])

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# # # 3. **Avian Influenza A(H3N8)**

* **Overview**: This strain of avian influenza has been reported in China, with three known human infections, including one fatality.& ;

* **Transmission**: The virus is primarily transmitted from poultry to humans, with no confirmed cases of human-to-human transmission. The risk of spread is currently considered low.& ;

* **U.S. Status**: There have been no reported human cases of H3N8 in the United States. However, the U.S. continues to monitor avian influenza strains due to their potential to mutate and pose broader health risks.

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While these viruses are under surveillance, it's important to note that none currently pose a significant threat to public health in the United States. Health authorities recommend standard precautions, such as regular handwashing, staying home when sick, and staying informed through official health channels.([New York Post][1])

Medical News and articles you can trust from around the world. All content is written and reviewed by qualified health, medical and scientific experts.

This seems like a great idea
04/23/2025

This seems like a great idea

04/08/2025
Wow
04/08/2025

Wow

04/08/2025
04/05/2025

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