02/21/2026
What You Can Do
Maintaining a healthy gut microbiome is a key factor in preventing colorectal cancer.
Dietary fiber, probiotics, prebiotics, synbiotics—products combining probiotics and prebiotics—and even f***l microbiota transplantation can help rebuild microbial balance and regulate immune and inflammatory pathways, Abdulqadir said.
Focus on Fiber and Whole Foods
From a dietary perspective, the most important step is to consistently follow an eating pattern that supports microbial diversity, especially one rich in dietary fiber. A high-fiber diet that includes fruits, vegetables, fermented foods, and prebiotic or probiotic sources helps maintain a healthier microbial balance and creates a gut environment less supportive of tumor development, Aryal said.
“Incorporating Mediterranean-style eating patterns is especially helpful because they emphasize whole grains, legumes, vegetables, and healthy fats that support microbial diversity,” he added.
Consider Targeted Supplements
Probiotics may help lower the risk of colorectal cancer. One well-studied strain, Faecalibacterium, has been shown in animal research to reduce gut inflammation and protect against colitis.
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Other probiotics, including certain Lactobacillus and Bifidobacterium strains, help strengthen the gut lining and support healthy cell growth—especially in people with a history of polyps—small growths on the lining of the bowel that can sometimes turn into cancer.
“When probiotics and prebiotics are used together as synbiotics, they help reduce inflammatory mediators and create a gut environment less favorable for tumor development,” Aryal said.
Doses and specific types can vary, so it’s best to talk to a doctor before trying them.
Colorectal surgeon Dr. Cedrek McFadden’s top advice is to keep things simple.
