01/26/2026
Low-dose naltrexone (LDN) is gaining interest as researchers explore its potential to support individuals living with chronic pain, inflammation, and immune-related conditions. Unlike traditional pain medications, LDN appears to work through unique pathways in both the nervous and immune systems.
Current studies are evaluating how LDN may:
• Briefly block opioid receptors to encourage natural endorphin production
• Interact with receptors involved in pain and immune responses
• Influence microglial cells in the brain to help reduce neuroinflammation
These effects suggest that LDN may represent a new class of therapies focused on central immune modulation, offering potential support for conditions such as fibromyalgia and other chronic pain disorders.
If you’re curious about LDN, speak with your healthcare provider. Compounding pharmacies prepare LDN in customized low doses and forms based on prescriber direction.
https://columbiacompounding.com/pain-management/