Kat Toups, MD - Functional Medicine Psychiatry & Dementia

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Kat Toups, MD - Functional Medicine Psychiatry & Dementia Regenerative, Precision, and Functional Medicine Psychiatry and Dementia

Functional medicine teaches that all parts of the body and brain can be affected by chronic illness, with the common denominator being Inflammation. The inflammation that affects your gut (diarrhea, bloating, constipation, acid reflux, etc.) or your thyroid (hypothyroidism, Hashimoto's) or your pancreas (diabetes, metabolic syndrome) or your joints (arthritis) can also affect your brain. Inflammat

ion in the brain can manifest as all of the psychiatric disorders (Depression, Anxiety, ADHD, OCD, Bipolar, PTSD, Psychosis) and also the Neurodegenerative Disorders (Alzheimer's, Mild Cognitive Impairment, Multiple Sclerosis, Parkinson's, ALS, etc.). The road to wellness then starts with the search for what is driving the inflammation, and putting out the source of that fire, rather than simply covering up one manifestation of the inflammation (like Depression or ADHD) without addressing it's root cause.

We've learned the importance of care and proper balance of the oral microbiome, as gum disease can potentially double yo...
02/07/2025

We've learned the importance of care and proper balance of the oral microbiome, as gum disease can potentially double your risk for Dementia.

Now there's a new study (link in the article to the study paper) that found the Stella Life homeopathic herbal mouthwash has selective antimicrobial effects that lets the good oral bacteria flourish, while eradicating the harmful strains of bacteria.

The other commercial mouthwashes tested eradicated all the bacteria – good and bad. This is not a desirable effect!

I used these Stella Life products for two recent dental surgeries and found them to be helpful.

BTW: I read the original study paper and there is no conflict of interest with the investigators and the Stella Life company. 😊

Researchers have found a natural mouthwash that seems to kill off nasty germs while nurturing friendly microbes.

Hooray!I hope I other companies become motivated to do the same thing.
18/06/2025

Hooray!

I hope I other companies become motivated to do the same thing.

Kraft Heinz said it will remove artificial dyes from its U.S. products by end of 2027 and stop making new products that contain the dyes.

REPLAY WEEKEND Friday 5/23 - Sunday 5/26FREE REVERSING ALZHEIMER"S SUMMIT - PLAYING NOWMy talk is on Day 2, and there wi...
15/05/2025

REPLAY WEEKEND Friday 5/23 - Sunday 5/26

FREE REVERSING ALZHEIMER"S SUMMIT - PLAYING NOW
My talk is on Day 2, and there will be a replay weekend where you can catch it later if you're interested. (We cover a lot of ground in this interview! And talk about lessons learned from our Precision Medicine Dementia Reversal trials, including our current randomized clinical trial in progress, and some info on the new Brain Biomarker testing.)

Alzheimer’s doesn’t start with memory loss.

It starts years—even decades—before, as silent triggers like inflammation, toxins, and nutrient deficiencies damage the brain.

At the Alzheimer’s Summit, uncover the hidden drivers of cognitive decline and learn exactly how to protect your brain.

✔️ The foods that fuel inflammation—and what to eat instead.

✔️ How mold, heavy metals, and other toxins accelerate memory loss.

✔️ The surprising connection between gut health and the risk of Alzheimer’s.

If you’ve been searching for answers beyond ‘there’s nothing you can do,’ this summit is for you. Hope is here!

👉

The premier online event for those determined to safeguard their memory, protect their loved ones, and reclaim their cognitive health.

I'd like everyone to know more about the remarkable Judy Benjamin.She was Dale Bredesen's patient zero – the first patie...
14/05/2025

I'd like everyone to know more about the remarkable Judy Benjamin.

She was Dale Bredesen's patient zero – the first patient that he worked with and helped her to reverse her dementia 13 years ago using a Functional Medicine/Precision Medicine approach that has become the basis of the research that we do together.

At age 80, she is currently walking across the US from California to Florida to raise awareness about Alzheimer's - that the disease is not only survivable, but reversible.

I had a fun interview with Judy on Sunday – I'm going to be the first interview on her new Alzheimer's Survivors podcast series.

I am my own patient zero – the first patient that I reversed Dementia with. Our stories were remarkably similar.

When I told her I realized my brain had come back online when I was able to hold a seven digit phone number in my head and dial the phone number, she said she has the exact same experience!

(Before that, it often took me multiple tries to even dial a phone number as I would get confused and have to start over.)

It's been 14 years for me that I was able to reverse things (a 3-year journey of applying every module I learned in Functional Medicine to myself) and go back to work, and I keep getting better over time instead of worse.

I'm so impressed with Judy Benjamin that I want people to know about the impact she is having! And please spread the word about her mission.

Judy Benjamin, PhD, begins an adventure of a life time. Join her as she walks over 3000 miles across America sharing the message of hope that cognitive decline can be prevented and reversed.

I'd like everyone to know more about the remarkable Judy Benjamin.She was Dale Bredesen's patient zero – the first patie...
14/05/2025

I'd like everyone to know more about the remarkable Judy Benjamin.

She was Dale Bredesen's patient zero – the first patient that he worked with and helped her to reverse her dementia 13 years ago.

At age 80, she is currently walking across the US from California to Florida to raise awareness about Alzheimer's - that the disease is not only survivable, but reversible.

I had a fun interview with Judy on Sunday – I'm going to be the first interview on her new Alzheimer's Survivors podcast series.

I am my own patient zero – the first patient that I reversed Dementia with. Our stories were remarkably similar.

When I told her I realized my brain had come back online when I was able to hold a seven digit phone number in my head and dial the phone number, she said she has the exact same experience!

(Before that, it often took me multiple tries to even dial a phone number as I would get confused and have to start over.)

It's been 14 years for me that I was able to reverse things (a 3-year journey of applying every module I learned in Functional Medicine to myself) and go back to work, and I keep getting better over time instead of worse.

I'm so impressed with Judy Benjamin that I want people to know about the impact she is having! And please spread the word about her mission.

Judy Benjamin, PhD, begins an adventure of a life time. Join her as she walks over 3000 miles across America sharing the message of hope that cognitive decline can be prevented and reversed.

Dr. David Perlmutter wrote this excellent and helpful summary and synthesis of the amazing benefits that melatonin offer...
18/01/2025

Dr. David Perlmutter wrote this excellent and helpful summary and synthesis of the amazing benefits that melatonin offers.

I often use high dose melatonin with the patients in my Precision Medicine Dementia clinical trials for all the reasons that Dr. Perlmutter has discussed.

IMMUNE
INFLAMMATION
ANTIOXIDANT
MITOCHONDRIAL PROTECTION and REPAIR

Melatonin: it's not just for sleep. Emerging research reveals melatonin’s powerful potential in brain health—helping to reduce inflammation, combat oxidative stress, and improve mitochondrial function. These mechanisms may play a critical role in addressing neurodegenerative diseases like Al...

I do think EXERCISE is one of our most powerful weapons to age well and gracefully. It's become clear that muscle streng...
18/01/2025

I do think EXERCISE is one of our most powerful weapons to age well and gracefully.

It's become clear that muscle strength is one of the biggest predictors of Longevity.

But the VO2 max, or the ability to quickly and effectively extract oxygen and send it to the tissues and brain, is another important predictor.

HIIT (High intensity interval training) is a great way to improve the VO2 max and the general cardiometabolic functioning.

----------------

Lifelong exercise promotes brain health in older adults

Proceedings of the National Academy of Sciences

Researchers assessed the white matter of the brain, which is composed of neurons and myelin, a fatty layer of insulation that surrounds neurons.

The study suggests lifelong exercise could be a therapeutic strategy for promoting brain health and reducing the risk of developing neurodegenerative conditions, such as Alzheimer’s and Parkinson’s disease.

Myelin, which tends to decrease as humans grow older, has two major functions: to protect neurons from insults and harm such as toxic byproducts generated by the brain, and to accelerate the communication between different neurons and regions of the brain.

(Myelin creates an insulating sheath around the neurons that allows the neuron cell impulses to be propagated or transmitted down the neuron to the next neuron.)

Other studies have shown aerobic exercise may preserve and enhance cerebral myelination throughout the adult lifespan, but how it worked remained unknown.

This research suggests that cardiovascular fitness and VO2 max may be crucial for the production and maintenance of myelin.

Individuals who maintain a regimen of physical activity throughout their lives may prevent brain deterioration during midlife and older adulthood.

I use the Ketogenic Diet in my Precision Medicine clinical trials for reversing dementia. But it's got some wide-ranging...
17/01/2025

I use the Ketogenic Diet in my Precision Medicine clinical trials for reversing dementia. But it's got some wide-ranging benefits in all kinds of psychiatric conditions as well.

Georgia Ede is one of the leading researchers, authors, and teachers of using ketogenic diets to improve mental health and psychiatric conditions.

Dairy of a CEO is an excellent interviewer! Hope you enjoy this. 


Dr Georgia Ede is a Harvard trained psychiatrist specialising in nutritional and metabolic psychiatry. She is the author of the book, ‘Change Your Diet, Chan...

The latest DEMENTIA STATISTICS are absolutely horrifying! Please keep the faith that there is a way to both prevent this...
16/01/2025

The latest DEMENTIA STATISTICS are absolutely horrifying!

Please keep the faith that there is a way to both prevent this and treat Dementia if we can catch things early enough. Our latest Precision Medicine randomized clinical trial will finish later this year, but our preliminary data is very promising.

(I'm still offering a free e-book on my website that covers the basics of the approach that I use, and I'm actually working on finishing a more definitive book about it right now. Stay tuned ...)

NATURE MEDICINE - 1/13/25

The number of US adults who will develop dementia each year is projected to increase from approximately 514,000 in 2020 to about 1 million in 2060, new research shows.

(Next 35 years - 1 million new US cases of dementia each year!!)

In addition, the lifetime risk of developing dementia after age 55 is estimated at 42%. The research showed that the relative growth in dementia cases is particularly pronounced for Black adults.

Rates were substantially higher in women, Black adults and APOE ε4 carriers, with lifetime risks ranging from approximately 45% to 60% in these populations.

1 million adults projected to develop dementia each year by 2060

Scientific evidence is now telling us that one of the best predictors of longevity is the strength of our muscles. All o...
31/10/2024

Scientific evidence is now telling us that one of the best predictors of longevity is the strength of our muscles. All of my patients in my dementia reversal clinical trials work on a combination of strength training, aerobics, balance training, and high intensity interval training.

I'm constantly impressed by my study patients, especially my patients in their mid 70s who never really exercised before. With the help of the excellent exercise trainer for my study, Mac Dodds, I watch their bodies transform, and also get to document the changes in their cognition, lipids, blood pressure, blood sugar, and inflammation.

If you need more inspiration than that, please see below. Exercise is one of the best validated ways to increase BDNF (brain derived neurotrophic factor) that helps to make new synaptic connections in the brain. 

-----------------

75-year-old CrossFit athlete (she's not 99)

5'5"
114 pounds
PhD in mathematics from NYU in 1972
JD law degree from Pace University

But I think her best "degree" is in her personal health fitness, and serving as an inspiration for all of us!

This is definitely inspiring me to step up my training. 🏋️‍♀️

Please watch: "Train Like A Universal Soldier - Eddie Grant | Muscle Madness" https://www.youtube.com/watch?v=uU9Y0W8s-0A --~--More https://www.youtube.com/p...

THIS IS SO SCARY! FDA and EPA NEED TO STEP UP. https://www.scientificamerican.com/article/pfas-in-pesticides-could-pose-...
14/09/2024

THIS IS SO SCARY! FDA and EPA NEED TO STEP UP.

https://www.scientificamerican.com/article/pfas-in-pesticides-could-pose-a-greater-multigenerational-threat-than-ddt/

PFAS contain chemical bonds that are extremely hard to break, making them difficult to get rid of once they are released into the world.

PFAS contamination has been documented in hundreds of species of wildlife from the far reaches of the Arctic to the tropics in the Pacific Ocean.

Very low concentrations of many PFAS have been linked to certain cancers, delays in childhood development and immune system dysfunction in humans.

Our study found that 14% of all conventional active ingredients in pesticides are PFAS. Worse yet, the long-lived chemicals comprise 30% of pesticide active ingredients approved in just the past 10 years, meaning that pesticide contamination with PFAS is trending upward and will likely increase in the coming years.

Right now, with summer coming to an end in the U.S., many farmers have already applied pesticides to try to suppress weeds, insects or fungi. That means tens of millions of pounds of forever chemicals were added to the environment this year alone and will remain there, in one form or another, for the birth of your grandchildren’s grandchildren and generations thereafter.

If the EPA fails to face this challenge, it will be responsible for burdening generations to come with increases in deadly, chronic diseases and toxic cleanup responsibilities that will, quite literally, last forever.

A looming and poorly regulated PFAS threat comes from these chemicals’ common use in pesticides on farms nationwide

This is really important information. This situation is called PANS or PANDAS in children, but they need to get a new na...
19/05/2024

This is really important information. This situation is called PANS or PANDAS in children, but they need to get a new name for adults besides PANS since that implies children.

It's just a tip of the iceberg for Psychiatry to say that people have to have Brain Antibodies in order to benefit from treatment Immune psychosis. They have such a limited number of known auto-antibodies to test for. But it's a start. 

Now if we can get Neurology and Psychiatry to expand the search for any indications of autoimmunity or immune dysfunction, and then test for all of the infections that affect the brain, as well as mycotoxins, then they will be cooking with gas.

The discovery of rogue antibodies behind paranoia, hallucinations, and other symptoms could bring a “paradigm shift” to psychiatry

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Functional medicine teaches that all parts of the body and brain can be affected by chronic illness, with the common denominator being Inflammation. The inflammation that affects your gut (diarrhea, bloating, constipation, acid reflux, etc.) or your thyroid (hypothyroidism, Hashimoto's) or your pancreas (diabetes, metabolic syndrome) or your joints (arthritis) can also affect your brain. Inflammation in the brain can manifest as all of the psychiatric disorders (Depression, Anxiety, ADHD, OCD, Bipolar, PTSD, Psychosis) and also the Neurodegenerative Disorders (Alzheimer's, Mild Cognitive Impairment, Multiple Sclerosis, Parkinson's, ALS, etc.). The road to wellness then starts with the search for what is driving the inflammation, and putting out the source of that fire, rather than simply covering up one manifestation of the inflammation (like Depression or ADHD or Dementia) without addressing it's root cause.