The New England Journal of Medicine

The New England Journal of Medicine The New England Journal of Medicine (NEJM.org) is the world's leading medical journal and website.
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A baby boy was transferred to a tertiary care hospital 5 days after birth. He had an intact manubrium but no corpus of t...
10/27/2025

A baby boy was transferred to a tertiary care hospital 5 days after birth. He had an intact manubrium but no corpus of the sternum, which had resulted in complete displacement of the heart outside the chest wall (shown in a video).

10/26/2025

๐‚๐š๐ฅ๐ฅ ๐Ÿ๐จ๐ซ ๐’๐ฎ๐›๐ฆ๐ข๐ฌ๐ฌ๐ข๐จ๐ง๐ฌ: ๐ˆ๐ฆ๐š๐ ๐ž๐ฌ ๐‡๐ข๐ ๐ก๐ฅ๐ข๐ ๐ก๐ญ๐ข๐ง๐  ๐ญ๐ก๐ž ๐‡๐ž๐š๐ฅ๐ญ๐ก ๐ˆ๐ฆ๐ฉ๐ฅ๐ข๐œ๐š๐ญ๐ข๐จ๐ง๐ฌ ๐จ๐Ÿ ๐‚๐ฅ๐ข๐ฆ๐š๐ญ๐ž ๐‚๐ก๐š๐ง๐ ๐ž

Our Images in Clinical Medicine section seeks striking, high-quality clinical images that illuminate the growing and evolving impact of climate change on human health for the second feature to be published April 2026.

10/26/2025

A 30-year-old man presented to the ophthalmology clinic with a 3-day history of recurrent, painful bumps on his left lower eyelid. He reported annual recurrences of similar lesions at the same site at the same site since adolescence, often triggered by psychological stress or sun exposure and with spontaneous resolution. Visual acuity and findings from a slit-lamp examination were normal. What is the most likely diagnosis? https://nej.md/IC10232025

Dr. Lisa Rosenbaum talks with Dr. Steven Lin, a Stanford P*P and AI implementation expert, about the promise and perils ...
10/25/2025

Dr. Lisa Rosenbaum talks with Dr. Steven Lin, a Stanford P*P and AI implementation expert, about the promise and perils of AI and its limits as a solution to the forever crisis of primary care.

10/25/2025

The newest Stats, STAT! animated video from ๐˜•๐˜Œ๐˜‘๐˜” ๐˜Œ๐˜ท๐˜ช๐˜ฅ๐˜ฆ๐˜ฏ๐˜ค๐˜ฆ explores the use of propensity scores โ€” a method of controlling for observed confounders in non-randomized studies.

A 34-year-old man with recent travel to Zimbabwe presented with a 4-day history of fever and generalized weakness. A pai...
10/24/2025

A 34-year-old man with recent travel to Zimbabwe presented with a 4-day history of fever and generalized weakness. A painful, crusted ulceration was noted on the parietal scalp.

10/24/2025

Do the benefits of bisphosphonates outweigh the risk of side effects? Dr. Ole-Petter R. Hamnvik, an endocrinologist at Brigham and Womenโ€™s Hospital in Boston, explains.

Uncertainty is ubiquitous in the practice of medicine. A new review characterizes clinical uncertainty and shows how tea...
10/23/2025

Uncertainty is ubiquitous in the practice of medicine. A new review characterizes clinical uncertainty and shows how teachers can guide learners to recognize, manage, and communicate uncertainty in practice.

10/22/2025

In this video clip, Dr. Asaf Bitton, a primary care physician at Brigham and Women's Hospital and an associate professor at Harvard Medical School, says we need to change primary care pedagogy.

A 23-year-old man with autism spectrum disorder and a history of severe constipation presented with abdominal pain, naus...
10/22/2025

A 23-year-old man with autism spectrum disorder and a history of severe constipation presented with abdominal pain, nausea, and vomiting. CT showed colonic distention, mural thickening, and perirectal fat stranding.

10/21/2025

How many doses of benzathine penicillin G are needed to treat patients with early syphilis?

A new video in our partnership with Dr. Glaucomflecken summarizes a recent trial investigating whether a single dose or multiple doses of benzathine penicillin G is needed for early syphilis.

Get free access to the article: https://nej.md/DrG28

A 52-year-old man with a history of splenectomy and hypogammaglobulinemia after CAR T-cell therapy for lymphoma 3 years ...
10/21/2025

A 52-year-old man with a history of splenectomy and hypogammaglobulinemia after CAR T-cell therapy for lymphoma 3 years earlier was admitted with septic shock. Encapsulated diplococci were seen in 20% of neutrophils.

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Over 200 Years of Medical Publishing

The New England Journal of Medicine (NEJM) is the worldโ€™s leading medical journal and website. Published continuously for over 200 years, NEJM delivers high-quality, peer-reviewed research and interactive clinical content to physicians, educators, and the global medical community.

Our mission is to bring physicians the best research and information at the intersection of biomedical science and clinical practice and to present this information in understandable and clinically useful formats that inform health care delivery and improve patient outcomes.

To these ends, the NEJM editorial team employs rigorous:


  • Editorial, peer, and statistical review processes to evaluate manuscripts for scientific accuracy, novelty, and importance.