The New England Journal of Medicine

The New England Journal of Medicine The New England Journal of Medicine (NEJM.org) is the world's leading medical journal and website.

The ๐ฅ๐จ๐ ๐š๐ซ๐ข๐ญ๐ก๐ฆ ๐จ๐Ÿ ๐ญ๐ก๐ž ๐ฆ๐ข๐ง๐ข๐ฆ๐ฎ๐ฆ ๐š๐ง๐ ๐ฅ๐ž ๐จ๐Ÿ ๐ซ๐ž๐ฌ๐จ๐ฅ๐ฎ๐ญ๐ข๐จ๐ง (๐ฅ๐จ๐ ๐Œ๐€๐‘) is the base 10 logarithm of the minimum angle of resolution of...
01/20/2026

The ๐ฅ๐จ๐ ๐š๐ซ๐ข๐ญ๐ก๐ฆ ๐จ๐Ÿ ๐ญ๐ก๐ž ๐ฆ๐ข๐ง๐ข๐ฆ๐ฎ๐ฆ ๐š๐ง๐ ๐ฅ๐ž ๐จ๐Ÿ ๐ซ๐ž๐ฌ๐จ๐ฅ๐ฎ๐ญ๐ข๐จ๐ง (๐ฅ๐จ๐ ๐Œ๐€๐‘) is the base 10 logarithm of the minimum angle of resolution of a visual target in minutes of arc. The logMAR is a standard way to represent visual acuity that can be averaged arithmetically. Each 0.1 increase in logMAR represents the loss of one line of letters on the eye chart, and doubling of the visual angle corresponds to a 0.3 increase in logMAR or the loss of three lines of letters on the eye chart. Converting a Snellen score to logMAR requires taking the base 10 logarithm of the reciprocal of the best corrected visual acuity. For example, to convert Snellen visual acuity of 20/200 on a standard vision chart to logMAR, one would take the reciprocal of the visual acuity (i.e., 200/20 = 10) and then calculate the base 10 logarithm of the result โ€” that is, logโ‚โ‚€ (10), which equals 1.

A 20-year-old woman presented with 9 days of pain and decreased vision in the right eye, as well as 2 weeks of a rash an...
01/19/2026

A 20-year-old woman presented with 9 days of pain and decreased vision in the right eye, as well as 2 weeks of a rash and gum swelling. Fever, dyspnea, and hemoptysis developed.

01/18/2026

Is 7 days long enough for a patient to receive antibiotic treatment for bacteremia, or should it be longer? Matthew J. Gwiazdon, MD, an infectious disease specialist affiliated with Beth Israel Deaconess Medical Center, addresses this question.

Sudden cardiac arrest in athletes may be attributable to cardiac and noncardiac causes. With diagnosis and treatment, a ...
01/18/2026

Sudden cardiac arrest in athletes may be attributable to cardiac and noncardiac causes. With diagnosis and treatment, a return to play may be reasonable. Prevention, emergency planning, and shared decision making are key.

01/17/2026

A previously healthy 20-year-old man presented to the dermatology clinic with a 4-week history of an itchy rash on his upper chest and shoulders. Two months before presentation, he had started a carbohydrate-restricted ketogenic diet for weight loss. Physical examination is shown. What is the most likely diagnosis? https://nej.md/IC01152026

01/16/2026

For a woman with asymptomatic severe aortic stenosis, would you support treatment with transcatheter aortic-valve replacement or surgical aortic-valve replacement?

Jacque Duncan, MD, describes the scientific foundations of restoring vision through the implantation of a retinal prosth...
01/15/2026

Jacque Duncan, MD, describes the scientific foundations of restoring vision through the implantation of a retinal prosthetic chip in persons with geographic atrophy.

Heart failure remains a leading cause of potentially avoidable hospital admissions throughout the United States and a si...
01/15/2026

Heart failure remains a leading cause of potentially avoidable hospital admissions throughout the United States and a significant driver of unnecessary, avoidable costs within value-based care programs.

In a baseline population of 3233 hospital emergency department (ED) visits for heart failure, which occurred over 12 months ending in June 2023 across six WellSpan Health acute care hospitals, 2868 (88.7%) resulted in inpatient admissions. Among those admissions, 2535 (96.0%) were deemed potentially avoidable by the U.S. Centers for Medicare and Medicaid Services (CMS) Prevention Quality Indicator (PQI) 08 heart failure admission quality indicator. Collectively, these admissions totaled US$27,618,825 in potentially avoidable total costs of care.

Through process improvements that modified triaging algorithms related to heart failure exacerbations where shortness of breath or lower extremity edema were present, 92.2% of triaged patients with heart failure were managed in an ambulatory setting, with 84.7% avoiding an ED visit within 24 hours.

The 12% cost reduction goal was almost achieved just 1 year into the intervention, with an 11.2% reduction in potentially avoidable admissions (CMS PQI 08, a core quality measure) and a US$3,352,248 reduction in total costs of care.

This novel intervention executed with Lean management principles was a pragmatic process improvement that can be readily replicated by other systems to reduce unnecessary, avoidable referrals of mild to moderate heart failure exacerbations to hospital EDs.

Published August 2025: In the phase 3 BaxHTN trial involving patients with uncontrolled or resistant hypertension, baxdr...
01/14/2026

Published August 2025: In the phase 3 BaxHTN trial involving patients with uncontrolled or resistant hypertension, baxdrostat added to background therapy led to a lower seated systolic blood pressure than placebo at 12 weeks.

An 80-year-old woman presented with a skin lesion on her left arm. Examination showed a brown lesion with eccentric hype...
01/14/2026

An 80-year-old woman presented with a skin lesion on her left arm. Examination showed a brown lesion with eccentric hyperpigmented asymmetric globules adjacent to a second, pink lesion with well-defined borders.

01/13/2026

Does your patient really need that peripheral IV โ€œjust in caseโ€? NEJM Clinician Editor-in-Chief Raja-Elie Abdulnour, MD, summarizes a recent article challenging the routine practice of maintaining idle PIVCs in clinically stable patients. Full summary: https://nej.md/4pCbsAP

01/13/2026

Statistically significant does not mean clinically significant. In the latest Stats, Stat! animated video from ๐˜•๐˜Œ๐˜‘๐˜” ๐˜Œ๐˜ท๐˜ช๐˜ฅ๐˜ฆ๐˜ฏ๐˜ค๐˜ฆ, Nigam and colleagues explain the minimal clinically important difference.

Address

860 Winter Street
Waltham, MA
02451

Opening Hours

Monday 8am - 4pm
Tuesday 8am - 4pm
Wednesday 8am - 4pm
Thursday 8am - 4pm
Friday 8am - 4pm

Telephone

+17818933800

Alerts

Be the first to know and let us send you an email when The New England Journal of Medicine posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.

Share

Share on Facebook Share on Twitter Share on LinkedIn
Share on Pinterest Share on Reddit Share via Email
Share on WhatsApp Share on Instagram Share on Telegram

Over 200 Years of Medical Publishing

The New England Journal of Medicine (NEJM) is the worldโ€™s leading medical journal and website. Published continuously for over 200 years, NEJM delivers high-quality, peer-reviewed research and interactive clinical content to physicians, educators, and the global medical community.

Our mission is to bring physicians the best research and information at the intersection of biomedical science and clinical practice and to present this information in understandable and clinically useful formats that inform health care delivery and improve patient outcomes.

To these ends, the NEJM editorial team employs rigorous:


  • Editorial, peer, and statistical review processes to evaluate manuscripts for scientific accuracy, novelty, and importance.