12/30/2025
Now enrolling: COVID-19 vaccine clinical trial for healthy adults [50 to 64 years of age]
Pursuing updated protection against COVID-19
As viruses continue to change, vaccines must be updated. Learn more about our updated COVID-19 vaccine clinical trial for healthy adults [50 to 64 years of age].
Dear patient,
Staying up to date on your COVID-19 vaccines is still the best way to prevent serious illness. However, as the virus continues to change, vaccines must be updated as well.
Our clinic is working with Pfizer and BioNTech to research if an updated COVID-19 vaccine is safe, and if it can help the immune system defend against new variants of the virus in healthy adults who are [50 to 64] years old and do not have risk factors for severe COVID-19. By participating in this clinical trial, you may reduce your risk of illness from COVID-19 while contributing to clinical research that could help protect millions of others around the world.
This clinical trial may be an option if you:
• Are [50 to 64] years old
• Are healthy with no major changes in your recent medical history
• Have not tested positive for COVID-19 within the last 3 months
• Have not received a COVID-19 vaccine within the last 3 months
• Do not have a medical condition that increases your risk of severe COVID-19, such as diabetes, cancer, obesity, chronic kidney disease, COPD, depression, etc.
• Do not have a history of severe allergic reactions associated with any vaccine
There are other study requirements that our team will discuss with you.
If this clinical trial is a good fit for you and you agree to take part, here is what you can expect:
• You will be assigned by chance (like flipping a coin) to receive 1 injection (shot) of either the study vaccine or placebo (injection with no vaccine).
• Participation lasts about [6] months and includes at least [4] study visits (some visits may be conducted by telephone). You may have an additional visit if you develop symptoms or test positive for COVID-19.
• [There is no cost to participate.] [You may be paid for completing on-site study visits.]
The study vaccine is a modified version of Pfizer-BioNTech’s original mRNA-based COVID-19 vaccine. The updated formulation is designed to improve protection against the latest circulating variant of the COVID-19 virus recommended by the [US Food and Drug Administration (FDA) and] World Health Organization (WHO).
If you are interested in taking part or would like more information, please reach out or scan the QR code below. We look forward to hearing from you.
Thank you,
Jasmine Sibert
Study Coordinator
(202) 853-9729