Patient-Centered Outcomes Research Institute - PCORI

Patient-Centered Outcomes Research Institute - PCORI PCORI funds patient-centered comparative clinical effectiveness research (CER).

PCORI-Funded Systematic Review Informs New Clinical Practice Guideline The American Society of Anesthesiologists has rel...
03/02/2026

PCORI-Funded Systematic Review Informs New Clinical Practice Guideline

The American Society of Anesthesiologists has released a new clinical practice guideline on perioperative pain management for adults and children, informed in part by a PCORI-funded systematic review on Peripheral Nerve Blocks for Postoperative Pain Management in Cardiothoracic Surgery.

Read more: https://pcori.me/4lCpLVh

3️⃣ Reasons To Apply: PCORI Advisory Panels1️⃣ Help shape PCORI's funding priorities2️⃣ Take an active role in advancing...
02/27/2026

3️⃣ Reasons To Apply: PCORI Advisory Panels

1️⃣ Help shape PCORI's funding priorities
2️⃣ Take an active role in advancing healthcare research in your community
3️⃣ Help improve the healthcare experiences of millions across the United States

Don’t miss this chance to make a difference! Applications are due in 1️⃣ week. Learn more & apply today: https://pcori.me/4aQPrZE

Submit Your Letter of Intent for the Engagement Award ProgramThrough this program, PCORI funds projects that build commu...
02/26/2026

Submit Your Letter of Intent for the Engagement Award Program

Through this program, PCORI funds projects that build communities’ capacity to engage in patient-centered CER and disseminate PCORI-funded research results to those who need them.

Learn more: https://pcori.me/4dxwpqM

02/25/2026

Is PCORI Funding a Fit for Your Research Idea?

Use PCORI’s decision tool to help assess whether your research idea aligns with one of PCORI’s patient-centered CER funding opportunities.

Review the decision tool: https://pcori.me/3JCiOFi

Older adults with complex healthcare needs — such as those living with multiple chronic conditions and functional limita...
02/24/2026

Older adults with complex healthcare needs — such as those living with multiple chronic conditions and functional limitations — often face gaps in care coordination, which could affect their health outcomes.

A PCORI-funded randomized controlled trial is comparing 2 approaches to determine which is more effective for older adults:

1️⃣ Structured annual wellness visits (AWVs) in primary care practice

2️⃣ Structured AWVs enhanced with Geriatrics Resources for the Assessment and Care of Elders (GRACE), an interprofessional care delivery model that includes facilitating co-management between the GRACE and primary care teams

Read more: https://pcori.me/40oszf8

Nutrition is a key component for managing overall health. 🍎 Several PCORI-funded patient-centered CER studies are explor...
02/23/2026

Nutrition is a key component for managing overall health. 🍎

Several PCORI-funded patient-centered CER studies are exploring how nutrition affects health and recovery across different conditions.

Read more on how PCORI-funded CER is helping to guide better-informed healthcare decisions: https://pcori.me/4jZ1Q1J

2️⃣ Weeks Left to Submit Your Advisory Panel Application!PCORI is seeking individuals with a range of knowledge and expe...
02/20/2026

2️⃣ Weeks Left to Submit Your Advisory Panel Application!

PCORI is seeking individuals with a range of knowledge and experience to help shape and guide its research funding priorities through its Advisory Panels on:

◼️ Clinical Effectiveness and Decision Science
◼️ Clinical Trials
◼️ Healthcare Delivery and Disparities Research
◼️ Patient Engagement
◼️ Rare Disease

Learn more & apply: https://pcori.me/4aATdGk

Catch the recording of PCORI 2026 & Beyond to learn what's ahead for PCORI in 2026. This year's program was another succ...
02/19/2026

Catch the recording of PCORI 2026 & Beyond to learn what's ahead for PCORI in 2026.

This year's program was another successful event filled with practical information, engaging discussions and updates you don’t want to miss! https://pcori.me/46iaa7f

The latest edition of PCORI’s Emerging Health Care Innovation Brief features recent FDA approvals, including the first t...
02/18/2026

The latest edition of PCORI’s Emerging Health Care Innovation Brief features recent FDA approvals, including the first treatment for children with Menkes disease, a rare X-linked genetic disorder.

Other topics to watch:
▫️ Antibody-oligonucleotide conjugates, an emerging therapeutic class to advance treatment for muscular dystrophies.
▫️ Gotistobart, an investigational monoclonal antibody designed to treat squamous non-small cell lung cancer.

Read more: https://pcori.me/40g7svl

Both dissemination and implementation are critical components of PCORI's efforts to facilitate the awareness, uptake and...
02/17/2026

Both dissemination and implementation are critical components of PCORI's efforts to facilitate the awareness, uptake and integration of evidence from PCORI-funded patient-centered CER into clinical practice to support patients, caregivers and others in making informed healthcare decisions.

Learn how PCORI is funding initiatives to get new evidence from PCORI-funded studies into the hands of people who can use it. https://pcori.me/4oaHBib

A PCORI-funded patient-centered CER study compared outcomes for 2 common treatments for aortic valve disease: ◻️ Transca...
02/16/2026

A PCORI-funded patient-centered CER study compared outcomes for 2 common treatments for aortic valve disease:

◻️ Transcatheter aortic valve replacement (TAVR), which requires no major surgery.
◻️ Surgical aortic valve replacement (SAVR), which typically involves open-heart surgery.

Results showed TAVR recipients were more likely to go directly home after treatment and less likely to go somewhere else for care than SAVR recipients. Read more: https://pcori.me/4aAoUkX

Meaningful engagement in patient-centered CER actively involves patients and others throughout the research process. PCO...
02/13/2026

Meaningful engagement in patient-centered CER actively involves patients and others throughout the research process. PCORI requires meaningful patient and partner engagement as a component of the research it funds. This commitment helps strengthen study relevance, leading to greater use and uptake of research results.

Learn more about why meaningful engagement is a critical piece of patient-centered CER: https://pcori.me/3LO2QIR

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