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Monday 8:30am - 5:30pm Tuesday 8:30am - 5:30pm Wednesday 8:30am - 5:30pm Thursday 8:30am - 5:30pm Friday 8:30am - 5:30pm

Patient-Centered Outcomes Research Institute - PCORI

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Patient-Centered Outcomes Research Institute - PCORI

PCORI funds patient-centered comparative clinical effectiveness research (CER).

08/15/2025

💻 Broad Pragmatic Studies PCORI Funding Announcement Town Hall
📆 Monday, August 18
🕰️ 11:30 am (ET)

During this webinar, PCORI will walk you through details of this funding announcement, including both programmatic and administrative requirements, applicant resources and more.

Register for the Town Hall: https://pcori.me/3Ix2kh0

08/14/2025

Closing Tomorrow: Submit Public Comment on Medical Care for Adults With Down Syndrome

Down syndrome is one of the most prevalent genetic causes of intellectual disability, occurring in 1 in 700 births in America.

PCORI is seeking public feedback on a draft report of a systematic review on Medical Care for Adults With Down Syndrome. Help shape future clinical guidelines by submitting your feedback here: https://pcori.me/47cLjmj

08/13/2025

Postpartum Hemorrhage (PPH) is persistent and excessive bleeding after childbirth and a serious cause of maternal morbidity and mortality.

PCORI recently published two reports related to PPH:
✔️ A scoping review on PPH care bundles and the use of tranexamic acid for the prevention and treatment of PPH.
✔️ A scoping review on the use of viscoelastic testing in the diagnosis and management of PPH.

Read the reports: https://pcori.me/4owQqEn

08/12/2025

PCORI is now accepting LOIs for several PCORI Funding Announcements!

◼️ Broad Pragmatic Studies
◼️ Addressing Rare Diseases
◼️ Phased Large Awards for Comparative Effectiveness Research
◼️ Advancing the Science of Engagement in Research
◼️ Improving Methods for Conducting Patient-Centered CER

As you prepare your LOI for submission, PCORI encourages you to register for an upcoming Applicant Town Hall. Learn more: https://pcori.me/4mdP4gj

08/11/2025

Uncontrolled high blood pressure affects millions and increases the risk of heart attack and stroke.

A PCORI-funded CER study compared two care approaches: clinic-based care and telehealth care.

Results showed blood pressure decreased among both groups; however, individuals receiving telehealth care reported higher rates of satisfaction and lower burden scheduling visits. Read more: https://pcori.me/3Lx7d7Z

08/08/2025

An estimated 200,000-250,000 Americans are living with Down syndrome.

PCORI invites public comments on a draft report reviewing Medical Care for Adults With Down Syndrome.

Help shape future clinical guidelines by submitting your feedback by Friday, Aug. 15. https://pcori.me/47cLjmj

08/07/2025

The latest edition of PCORI’s Emerging Health Care Innovation Brief highlights an updated list of FDA-approved medical devices using AI. It also features FDA approval of SIR-Spheres Y-90 resin microspheres to locally control liver cancer tumors that cannot be removed by surgery.

Additional topics to watch:
✔️ AI-enabled digital molecular pathology devices for personalized cancer care
✔️ Zoliflodacin, a new antibiotic for treating uncomplicated gonorrhea

Explore emerging therapies: https://pcori.me/4mnWKvO

08/06/2025

Public Comment Period Closes Tomorrow: Performance of Fusion Procedures for Degenerative Disease of the Lumbar Spine

Nearly 1 in 3 Americans develop degenerative disease of the lumbar spine by age 65.

Your insights on this draft systematic review can help shape future updates to clinical guideline recommendations and support more informed, evidence-based care. https://pcori.me/4lvwjVc

08/05/2025

After treatment from colorectal cancer, follow-up testing helps monitor for potential recurrence. However, there is uncertainty as to what type and frequency of follow-up can best in detecting cancer recurrence and improving overall survival.

A PCORI-funded CER study compared outcomes for groups who received more frequent versus less frequent follow-up scans and blood tests. The study found the test frequency was not associated with key health indicators — including the ability to detect cancer recurrence.

Read more: https://pcori.me/3poqavV

08/04/2025

Register for !

Join patients, caregivers and members of the broader healthcare community for this free, 2 day event focused on advancing patient-centered CER.

As an attendee, you’ll have the opportunity to:
✔️ Connect with like-minded individuals from across the country while expanding your professional network
✔️ Gain new perspectives on the importance of patient engagement in research
✔️ Explore the latest findings from PCORI-funded CER and related projects

Register: https://pcori.me/3TvVg6u

08/01/2025

Join PCORI on Aug. 22 for an information-rich webinar on the Cycle 3 2025 Advancing the Science of Engagement in Research PCORI Funding Announcement!

During this webinar, PCORI will walk you through details of this funding announcement, including both programmatic and administrative requirements, applicant resources and more.

Register for the Town Hall here: https://pcori.me/3Ix2kh0

07/31/2025

Public Comment Period Closing Next Week: Fusion Procedures for Degenerative Disease of the Spine

PCORI is seeking public feedback on a draft report of a systematic review on the Performance of Fusion Procedures for Degenerative Disease of the Lumbar Spine.

Your insights on this draft systematic review can help shape future updates to clinical guideline recommendations and support more informed, evidence-based care. https://pcori.me/4lvwjVc

Address

Washington D.C., DC

Opening Hours

Monday	8:30am - 5:30pm
Tuesday	8:30am - 5:30pm
Wednesday	8:30am - 5:30pm
Thursday	8:30am - 5:30pm
Friday	8:30am - 5:30pm

Website

http://www.pcori.org/

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